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《Journal of Anhui Traditional Chinese Medical College》 2007-05
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Comparison of Protective Effect of Shaoqiduogan Extracted by Different Methods on Immunological Liver Injury in Mice

SHAO Fu-rong,WEI Wei,LIU Hao,SUN Wu-yi,LI Xiang(Institute of Clinical Pharmacology of Anhui Medical University, Anhui Hefei 230032,China)  
Objective: To compare the protective effects of Shaoqiduogan(SQDG) extracted using different methods on immunological liver injury in mice.Methods: The model of immunological liver injury in mice was induced by injection of Bacillus Calmette Guerin(BCG) and lipopolysaccharide(LPS) from tail vein.The alanine aminotransferase(ALT),aspartate aminotransferase(AST),malondialdehyde(MDA)content,superoxide dismutase(SOD) and glutathione peroxidase(GSH-Px) activities in liver homogenate were assayed by spectrophotom etry.Results:Compared with total glucosides of paeony(TGP) 105 mg/kg+total saponin of astragalus mongholicus(ASTs) 15 mg/kg,SQDG 120 mg/kg significantly decreased the serum transaminase levels,MDA production,while had no significant effects on other indices.Conclusion: SQDG 120 mg/kg and TGP 105 mg/L+ASTs 15 mg/kg have different pharmacological effects on the model of immunological liver injury in mice.
【Fund】: 国家高科技研究计划中药现代化专项(2002AA2Z3235);; 安徽省2006年度科技攻关计划项目(06013133B);; 高校博士点基金(20060366003);; 安徽省人才开发资金资助项目(2001Z023)
【CateGory Index】: R285.5
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【Citations】
Chinese Journal Full-text Database 4 Hits
1 Yan Yongqing (China Pharmaceutical University Nanjing 210009);Synergism Factors of Material Base in Compound Prescription of Traditional Chinese Medicine[J];World Science and Technology;2001-02
2 ZHOU Qiang,LI Zhan guo (Department of Rheumatology and Immunology, People's Hospital, Peking University, Beijing 100044, China);Pharmaceutical effects of total glucosides of peony and its application in autoimmune disease[J];Chinese Journal of New Drugs and Clinical Remedies;2003-11
3 WANG Hua,WEI Wei, YUE Li,WANG Ni ping ,GUI Shuang ying,WU Li,SUN Wu yi,XU Shu yun (Institute of Clinical Pharmacology , Anhui Medical University, Hefei 230032,China);Protective effect of total glucosides of paeony on immunological liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide[J];Chinese Pharmacological Bulletin;2004-08
4 Shuang-Ying Gui, Wei Wei, Hua Wang, Li Wu, Wu-Yi Sun Cheng-Yi Wu, Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui Province, China Shuang-Ying Gui, Department of Pharmacy, Anhui College of TCM, Hefei 230031, Anhui Province, China;Protective effect of fufanghuangqiduogan against acute liver injury in mice[J];世界胃肠病学杂志(英文版);2005-19
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Ma Fei1,2 Li Yubao2* Pei Lanying2 Lu Jianbiao2 (1College of Life Science,Shandong Normal University,Jinan,250014,China;2College of Agriculture,Liaocheng University,Liaocheng,252059,China);Effect of Milkvetch on Broiler Immunity[J];Anhui Agricultural Science Bulletin;2007-05
2 HU Cheng-mu,JIANG Hui,LIU Hong-feng,LI Rong,LI Jun (School of Pharmacy,Anhui Medical University,Hefei 230032);Effects of LJTF on immunological liver injury in mice[J];Anhui Medical and Pharmaceutical Journal;2008-04
3 CHEN Fang-jun1,2,WANG Jia-jia1,LI Jun1(1.Anhui Medical University,Hefei,230032;2.Anqing Medical College,Anqing,246003);Protective effect of polysaccharides from yu-ping-feng powder on immunological liver injury in mice[J];Anhui Medical and Pharmaceutical Journal;2008-04
4 QIU Ji1,GUI Shuang-ying2(1.Department of Pharmacy,First Renmin Hospital,Hefei 230061;2.School of Pharmacy,Anhui College of Traditional Chinese Medicine,Hefei 230031);Protective effect of astragalus extract on acute liver injury in mice[J];Anhui Medical and Pharmaceutical Journal;2009-06
5 Yang Minghui Lu Junzhang Dou Yongqi Liu Yi Deng Xinli(Department of Traditional Chinese Medicine,PLA General Hospital,Beijing 100853);Effects of Baoyuanhuoxue Granula on State of Senile Type Ⅱ Diabetes before Thrombus[J];China Journal of Traditional Chinese Medicine and Pharmacy;2006-10
6 HAO Wei-xin, DONG Zhen-hua (Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China);Discussion on modif ied Shenxian decoction treating connective tissue disease (CTD) combined with pulmonary interstitial f ibrosis (PIF)[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-08
7 LIU Jing-li,WANG He,FU Shao-ping,JIN Feng-xie,YU Hong-shanSchool of Biological & Food Engineering,Dalian Polytechnic University,Dalian 116034,China;Purification of astragalosides from biotransformates with macroporous resin[J];Journal of Dalian Institute of Light Industry;2007-02
8 ZHANG Zong-shen,WANG Zi-qian(School of Biological & Food Engineering,Dalian Polytechnic University,Dalian 116034,China);Effects of culture conditions on the saponin accumulation in Astragalus membranaceus callus[J];Journal of Dalian Polytechnic University;2009-03
9 LIU Hong-bai~(1,2), LU Tong-yan~(2), ZHANG Chun-yan~(3), SUN Da-jiang~(2),BAI Xiu-juan~1 (1.Northeast Agriculture University,Harbin 150030,China;2.Heilongjiang River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Harbin 150070,China;3.Heilongjiang Traditional Chinese Medical University,Harbin 150030,China);Effects of the aqueous extract of astragalus root Astragalus membranaceus on immunity and antioxidation in Amur sturgeon (Acipenser schrencki Brandt)[J];Journal of Dalian Fisheries University;2006-03
10 SHI Peng Department of Nephrology, PLA 451 Hospital, Xi'an 710054, China;Effects of total glucosides of paeony on active Heymann nephritis in rats[J];Journal of The Fourth Military Medical University;2005-18
China Proceedings of conference Full-text Database 1 Hits
1 Hu Chengmu Jiang Hui Liu Hongfeng Li Rong Li Jun (School of Pharmacy,Anhui Medical University,Hefei 230032);Protective effect of Lonicera japonica total flavone(LJTF)on immunological liver injury in mice[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LU Jing-tao,CHEN Min-zhu(Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032);Effect of compound astragalus extract on TNFα、NO and IL-1 secreted by rat peritoneal macrophages induced by lipopolysaccharide[J];Anhui Medical and Pharmaceutical Journal;2006-05
2 NIE Xiao-hua~1,SHI Bao-jun~2,AO Zhong-hua~3,YIN Guang-yao~3,TAO Wen-yi~3(1.College of Biological and Environmental Engineering,Zhejiang University of Technology,Huangzhou 310032;2.Guangdong VTR Bio-tech Co.,LTD.,Zhuhai 519060;3.College of Biotechnology,Southern Yangtze University,Wuxi 214036);Extraction of the Astragalus Polysaccharides andits Effects on the Lymphocytes Proliferation[J];Journal of Anhui Agricultural University;2004-01
3 HU Shi Jun ZHU Hui YANG Zeng Ming (College of Life Science, Northeast Agricultural University, Harbin 150030, China);Prostaglandin D_2 and Its Receptor in Mammalian Reproductive System[J];Chinese Journal of Zoology;2004-03
4 ZHAO Li juan, LI Hong, YANG Shi jie(Dept.of Pharmacology, School of Basic Medical Sciences,Jilin University,Changchun 130021,China);Protective Effect of Membranous Milkvetch Root Injection from Acute Hepatic Injury in Mouse Induced with D-GalN[J];Journal of Jilin University of (Medicine Edition);2003-03
5 HT5SS][KH2D][WT5BZ]YANG He song [WT5BX](Chengde Medical College,Hebei Chengde 067000,China)[KH2D][WT5HZ];ANTITUMOUR EFFECT OF COMMON ANTHOXANTHIN OF SCUTELLARA'S STEM AND LEAF AND PARTS OF ITS MONOMERS[J];JOURNAL OF CHENGDE MEDICAL COLLEGE;2000-03
6 HUANG Jian,QIN Hua-li,HUANG Xian-kai,et al.(Trauma Center,Institute of Surgery Research,Daping Hospital,Third Military Medical University,Chongqing 400042,China);Effect of CRH on phagocytosis of rat enterocoelia macrophage[J];Journal of Traumatic Surgery;2006-01
7 DONG Jun 2, LIU Jian Yong 1, WAN Mo Bin 1, TANG Xian Tuan 3, ZHU Ju Zhen 1 (1. Department of Infectious Disease, Changhai Hospital, Second Military Medical University, Shanghai 200433, China; 2. Department of Gastroenterology, Traditional Chinese;Cellular immunoregulation of Traditonal Chinese Medicine Huangqi in treating patients with chronic hepatitis B by intravenous injection[J];Academic Journal of Second Military Medical University;2001-07
8 LIN Jing-hua, CHEN Hui-sun, HU De-yao, LIU Liang-ming (Research Institute of Field surgery, Daping Hospital, Third Military Medical University, Chongqing 400042,China);Effects of ginsenoside on immunomodulation after traumatohemorrhagic shock in rats[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;2000-04
9 ZHOU Jun1, CHEN Dun-jin2, LIAO Qin-ping2, YU Yan-hong1 1Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; 2Department of Gynecology and Obstetrics, First Affiliated Hospital, Beijing Medical University, Beijing 100710, China;Impact of PBDE-209 exposure during pregnancy and lactation on immune function of offspring rats[J];Journal of Southern Medical University;2006-06
10 ZHANG Li-jun, LI Bo, ZHONG Li, WANG Xun, LI Jian-song, ZHUANG Jun-han, YE Zhi-zhong. Department of Rheumatology, Xiangmihu Branch of Shenzhen Futian People′s Hospital, Guangdong 518040, China;Study on B lymphocyte subsets in periphral blood of patients with systemic lupus erythematosus and its relationship with humour immunity[J];Chinese Journal of Rheumatology;2005-01
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Sun Chcngwen,Lǚ Wenwei, Lei Chunli,Wu Yan,Chen Yu)(Dept.of physiogy; Dept.of physiologcal Central lad.,Basic College of Med. Sci.;Elect roph ysiological Lab.of the First Teaching Hospital);Effects of Astragal us saponins on experimental heart fail ure([J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1994-02
2 Yang Shijie, Zhang Wenjie, Jiang Yan·, Wei Junjie, Zhang Hongiun (Department of Pharmacology,Centrai Laboratory of Physiology, Department of Organic Chemistry);Sodium channel blockadeeffectofthe secondary extract XIII-2of scorpion venom from Buthus martensii Karasch[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1994-03
3 Qiu Shicui,Li Boqing,Li Haibin (Binzhou Medical College,Binzhou,Shandong Province 2 5660 3);EFFECT OF ASTRAGALUSMEMBRANACEUS(AM) ON LYMPHOCYTE PROLIFERATION AND INTERLEUKIN-2 (IL-2 ) PRODUCTION OF MICE[J];JOURNAL OF BINZHOU MEDICAL COLLEGE;2000-03
4 ZHOU Yi Qian 1, LIU Yu Lin 2, LIU Qing Zhen 1, LI Jin Lan 1 1Department of Internal Medicine, the First Affiliated Hospital of Xinxiang Medical College, Weihui 453100, China, 2Experimental Animal Center, Fourth Military Medical Univer;Effect of Astragalus root injection on T cell subsets of pulmonary tuberculosis patients and its short term curative effect[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1999-10
5 Wang yong,Hu zhiqian,Chen zhigang,Zhang lingzhen,Wang yuanhe,Department of General Surgery,Chang Zheng Hospital,Second Miliary Medical University.Shanghai 200003;EFFECT OF ASTRAGALUS ON CELLULAR IMMUNE FUNCTION OF RATS WITH OBSTRUCTIVE JAUNDICE[J];JOURNAL OF HEPATOBILIARY SURGERY;2000-01
6 Liu Hui,Li Jinrong,Hu Chuanzhen.College of stomatology of Hubei medical University,Wuhan(430079);Study of the Immunoenhancement and Anti-cancer Effect of Astragalus Membranaceus on Human Squamous Cell carcinoma Cell Line GNM[J];STOMATOLOGY;1999-02
7 Gao Benbo; Dai Liming; Xu Shuyun(Institute of Natural Drugs 261042);THE SCAVENGING ACTIVITIES OF TGM AND TGP ON FREE RADICALS[J];JOURNAL OF WEIFANG MEDICAL COLLEGE;1996-01
8 Sun Jiping,Xiao Wei;The Induction of IL-2 and IFN-γ in Human Lung Tumor Cell Lines by Astragulus[J];SHANDONG MEDICAL JOURNAL;2000-04
9 Zhang Lilan; Liang Guodong; Liu Yongqing et al(State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052);Study on Anti-rhinoviral Effect of A Compound IFN Mixture[J];CHINESE JOURNAL OF BIOLOGICALS;1998-01
10 Li Qiangzhong,Huang Chengjun,Jiao Lihua, Pan Shijun (People's Hospital of Hangting District,Weifang City,Shandong,Weifang 261100);Clinical and laboratory studies on treating chronic active hepatitis with Inj. Radix Astragali[J];Shanghai Medical & Pharmaceutical Journal;1997-07
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