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《Journal of Anhui Traditional Chinese Medical College》 2007-06
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Change of P300 in Hepatolenticular Degeneration Patients with Treatment Combining Traditional Chinese and Western Medicine

TONG Jian-bing,WANG Xiao-yan,GAO Ning-bin(Department of Neurology,the First Affiliated Hospital of Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China)  
Objective: To observe the change of P300 in hepatolenticular degeneration(HLD) patients with treatment combining traditional Chinese and western medicine.Methods: P300 of 30 HLD patients was analysed before and after one-month treatment by the HLD-Relief decoction supplemented with copper-clearing drug,and the result was compared with that of 30 patients in normal control group.Results:Compared with that of normal control group,the P300 latency was prolonged(P0.01)and the P300 amplitude was lower(P0.01)in HLD patients;after treatment,the P300 latency was shortened(P0.05),but alteration of the P300 amplitude was not significantly different.Conclusion: Treatment combining traditional Chinese and western medicine produces a marked effect on cognitive dysfunction in HLD patients.
【CateGory Index】: R742.4
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