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Xu Guansun,Wang Jian,Shen Dekai,et al (Institute of acupuncture and meridian,Anhui college of TCM,Hefei,230038)  
Acute model of gastric mucosal damage induced by brain ischemia in rat was established.Cerebral blood flow(r CBF),gastric mucosal blood flow(GMBF),gastric mucosal lesion index(LI),the contents of nitric oxide(NO)in blood,gastric mucosal and cortex tissue were detected.The protective effect of electroacupuncture(EA) on the gastric mucosal damage during cerebral ischemia were studied.The results were follows:EA may show the protective effect on the gastric mucosal damage induced by brain ischemia after 1h in rat.By pretreatment with the precursor of NO-L arginine(L arg)may also show the gastric protective effect of EA,but by pretreatment with NO synthesis inhibitor N ω nitro L arginine(L NNA)could not show the gastric protective effect of EA in rat.It is suggested that the protective effect of EA on the gastric mucosal damage induced by brain ischemia in rat was mediated through activation of L arg-NO pathway.
【Fund】: 国家攀登计划和安徽省教委资助
【CateGory Index】: R246.6
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Chinese Journal Full-text Database 5 Hits
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Chinese Journal Full-text Database 9 Hits
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1 XU Meng;ZHo OU Yue-hong;LIAO Shang-shang;MO Xiao-shu;JIANG Yan;Endocrine Department,the Chinese Medicine Hospital of Liuyang City;;To Observe the Clinical Curative Effect of Acupoint Injection of Mecobalamin Combined with Itopride in the Treatment of Diabetic Gastroparesis[J];糖尿病新世界;2016-04
2 SUO Xiaoyan;DU Zhaohui;LI Jianguo;WANG Yanlin;CHEN Weimin;Dept.of Anesthesiology,Henan Province People's Hospital;Dept.of ICU,Zhongnan Hospital of Wuhan University;;Protective Effects of Electro-Acupuncturing Zusanli Points on Hemorrhagic Shock in Dogs[J];武汉大学学报(医学版);2016-01
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