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《Chinese Journal of Cancer》 1993-01
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SELENIUM AND GSH-PX ACTIVITIES IN NPC PATIENTS BEFOREAND AFTER RADIOTHERAPY

ZHENG Mei-lian HUANG Jia-chen YANG Rong-pu ZHANG FengSU Yung FENG Gong-kan MEI Chen-gen ZHENG Kuo-shan (Cancer Institute Sun Yat-sen University of Medical Sciences. Guangzhou 510060)  
The blood samples colleted from 68 nasoparyngeal carcinoma(NPC) patients in stage 11, 111, IV before and at the end of radiotherapy and from46 healthy persons were analysed for selenium (Se) and glutatione peroxidase (GSH-PXActivities No significant difference in selenium level was found between the NPC patients before radiotherapy and control group (P0.05). The selenium level in patients after radiotherapy was significantly lower than that in the normal control group (P P.05). The selen-iumlevel in NPC patients of different clinical stage after radiotherapy were lower than that in the control group. Furthermore, the selenium content of these patients decreased gradually with disease development However, the GSH-PX activities in NPC patients not only before radiotherapy, but also at the end of it were significantly lower than those of the normal control group(P0.01). The enzyme activities in patients before and after radiotherapy of different clinical stages were lower than those of control group(F = 9.76P 0.0001). In addition, it was found that the activities of GSH-PX in patients before and after radiotherapy decrease gradually with clinical stages of disease development. These suggested the determination of GSH-PX activities in NPC patients may be helpful in monitoring the clinical progression of the disease.
【Fund】: 中山医科大学中青年科学基金
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【References】
Chinese Journal Full-text Database 1 Hits
1 ZHENG Mei-lian,MAO Zhi-da,HUANG Hui-ying (Cancer Institute, Cancer Center Sun Yat-sen University, Guangzhou, Guangdong 510060,China);Effect of Vitamin A and E on Antioxidation in NPC Patients with Radiotherapy[J];Acta Nutrimenta Sinica;2005-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Wang Xuefeng et al (Dept.of Biology, Suzhou University,Suzhou 215151);Purification and Characterization of Superoxide Dismutase from Garlic[J];Journal of Anhui Agricultural Sciences;2001-03
2 YAN Rong et al(Zunyi Medical College,Zunyi,Guizhou 563003);Research Progress on Morphological Classification and Immunization of Insect Hemocytes[J];Journal of Anhui Agricultural Sciences;2010-18
3 FANG Hao et al(Research Center for Harmful Algae and Aquatic Environment,Jinan University,Guangzhou,Guangdong 510632);Study on the Acute Toxicity of PCBs to Two Species of Microalgae[J];Journal of Anhui Agricultural Sciences;2011-15
4 MIAO Zeng-liang et al(Zhejiang Key Laboratory of Ocean Aquaculture Equipment & Engineering Technology,Zhejiang Ocean Univerisity,Zhoushan,Zhejiang 316000);Effects of Exhaustive Exercise on the Activities of SOD and AKP in Nibea japonica[J];Journal of Anhui Agricultural Sciences;2012-18
5 ZHAO Shu-jun,CAI Sheng-rong,FANG Zhi-bin,Liu Yong,WANG Yuan-xun(Department of Integrated Traditional Chinese and Western Medicine,AnhuiCollege of Traditional Chinese Medicine, Anhui Heifei 230038, China);Changes and Meanings of IL-8, MDA, and SOD in Rats with Pulmonary Qi deficiency of Chronic Bronchitis[J];Journal of Anhui Traditional Chinese Medical College;2005-02
6 HUANG Jia-chen, YANG Rong-pu, FENG Gong-kan, MEI Zheng-en(Cancer Institute, Sun Yat-sen Universityof Medical Sciences)LI Jing-lien, LING Qi-nan, WEN Fa-lin, TAN Qun-feng (Cancer Institute of Sihui County, Guangdong);DETERMINATION OF SELENIUM CONTENTS IN SERUM AND HAIR OF NASOPHARYNGEAL CARCINOMA (NPC) PATIENTS AND HEALTHY PERSONS IN NPC HIGH RISK AREA, SIHUI COUNTY[J];Chinese Journal of Cancer;1986-01
7 LUO Huei-ling WU Yin-tang Cancer Institute. Sun Yat-sen University of Medical Sciences;EFFECT OF SODIUM SELENITE ON THE ANTIGEN EXPRESSION OF EPSTEIN-BARR VIRUS[J];Chinese Journal of Cancer;1986-04
8 YANG Rong-pu HUANG Jia-chen FENG Gong-kanMEI Cheng-en (Cancer Institute , Sun Yat-sen University of Medical Sciences);SELENIUN1M BLOOD AND HAIR OF HEALTH PERSON FROM NPC HIGH AND LOW RISK AREA OF GUANGDONG PROVINCE[J];Chinese Journal of Cancer;1988-02
9 Zhan Jiahong (Department of Biology, Hanshan Teachers' College, Chaoahou Guangdong 521041);Effect of Superoxide Dismutase on Canceration Caused by Oxygen Free Radicals[J];AMINO ACIDS & BIOTIC RESOURCES;1997-03
10 ZHANG Xiao ZHANG Xi ZHAO Cheng-fa CHEN Yu-qin(Yunnan Agricultural University,Kunming Yunnan 650201);Changes of Lipid During the Processing of Dry-cured Ham and Its Impact on Flavor[J];Modern Agricultural Science and Technology;2012-10
China Proceedings of conference Full-text Database 6 Hits
1 QIAO Xiuting, BAI Dongqing, QIAO Zhiyi, WEI Dong, MAO Haitao, WANG Guangyu (Tianjin Key Lab of and Aqua -Ecology, the Department of Fishery Science, Tianjin Agricultural College, Tianjin 300384, China);Effects of Herb Medicine on Antioxidatives and Lysozyme Activityin Jade Perch[A];[C];2010
2 Liu Ye-ling Wang chun-bo (Taian Central Hospital, Tai'an, 271000; 1. Department of Pharmacology, Qingdao University Medical College, Qing' dao 266021);Antioxidative effect of Ipomoea Batatas Poir Cv Anthocyanins on mice irradiated by ~(60)Co gamma ray[A];[C];2005
3 ;Cold Acclimation and Cold Hardiness Property on Various Types of Turfgrasses[A];[C];1996
4 Xu Ye Shi Guoxin Xu Qinsong Wang Xue Ding Bingzhong(College of Life Sciences,Nanjing Normal University,Nanjing 210097,P.R.China);Effects of Exogenous Pro on Resistance of Trapella Sinensis Olive to Cd~(2+) Stress[A];[C];2007
5 ;Scavenging of Free Radical(O_2~(-·)) by Sixteen Species of Commonly Used Umbelliferae Family Medicinal Plant[A];[C];1998
6 Li Linfeng,Zhao Ying,Zhou Yanmin(Nanjing Agricultural University,Nanjing 210095);Effects of emulsifier on meat quality and antioxidant capacity of finishing pigs[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 HUANG Jia-chen, YANG Rong-pu, FENG Gong-kan, MEI Zheng-en(Cancer Institute, Sun Yat-sen Universityof Medical Sciences)LI Jing-lien, LING Qi-nan, WEN Fa-lin, TAN Qun-feng (Cancer Institute of Sihui County, Guangdong);DETERMINATION OF SELENIUM CONTENTS IN SERUM AND HAIR OF NASOPHARYNGEAL CARCINOMA (NPC) PATIENTS AND HEALTHY PERSONS IN NPC HIGH RISK AREA, SIHUI COUNTY[J];Chinese Journal of Cancer;1986-01
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