Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《CHINESE JOURNAL OF CANCER》 2000-04
Add to Favorite Get Latest Update

Induction of human gastric cancer MGC 80-3 cell apoptosis by photoactivated curcumin

CHEN Rui chuan, SU Jin hua, MA Sheng ping, et al Cancer Research Center of Xiamen University, Xiamen 361005, P R China  
Objective: To investigate the effects of photoactivated curcumin on induction of apoptosis in human gastric cancer cell line MGC 80 3 Methods: MGC 80 3 cell was treated with curcumin plus fluorescence Experiments of dye exclusion counting and Giemsa staining were conducted to determine the cell survival, morphology, and apoptotic index The analysis of DNA fragmentation and cell cycles were performed by DNA electrophoresis and flow cytometer respectively Results: Cell viability dropped down dependent on the curcumin concentration and treatment time Contrarily, the apoptotic index increased dependent on the curcumin concentration and the typical apoptotic morphology “ladder bands”could be seen on DNA electrophoresis in 5 μmol/L curcumin plus light treated cells By analysis with flow cytometry, cell cycles showed G 2/M arrest after treatment with 2 5 and 5 μmol/L curcumin plus light, suggesting an association between G 2/M arrest and MGC 80 3 cell apoptosis induced by photoactivated curcumin Conclusion: Photoactivated curcumin has the effect of inducing cell apoptosis in MGC 80 3 cells, suggests a potential application of photodynamic therapy for tumor
【Fund】: 福建省自然科学基金!(C9710 8)资助
【CateGory Index】: R735.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 9 Hits
1 TIAN Xiuhong(College of Occupation Technical,Hebei Normal University,Shijiazhuang 050031);The Anti-cancer Function of Active Components in Vegetables and Reasonable Meal[J];Journal of Changjiang Vegetables;2008-10
2 SHI Wen-rong1,ZHANG Zhen-lin2,LIU Yan1(1.Department of Integrated Traditional Chinese and Western Medicine,Fujian College of Traditional Chinese Medicine,Fuzhou 350108,China);Effect of illumination on curcumine-induced apoptosis in human breast cancer(MCF-7) cells[J];Journal of Guangdong Medical College;2009-02
3 XU Chuan-shan 1,2,Albert Wing Nang Leung 21.Department of Laser Medicine,Second Affiliated Hospital,Chongqing Medical University,Chongqing 400010;China2.Department of Chinese Medicine Education Division,School of Chinese Medicine,Hong Kong Baptist University,Hong Kong;Photodynamic therapy mediated by Chinese herd photosensitizer[J];Laser Journal;2004-06
4 ZENG Xia-bo1,XIA Xin-shu2,YU He-ping2,BAI Ding-qun2,TAN Yong1,HE Yong1,XU Chuan-shan11.Center of Physical Medicine and Rehabilitation,Second Affiliated Hospital,Chongqing Medical University,Chongqing 400010,China;2.Department of Rehabilitation Medicine,First Affiliated Hospital,Chongqing Medical University,Chongqing,400016,China;Inhibitive action of photoactive curcumin on human breast cancer[J];Laser Journal;2008-02
5 CHEN Rui chuan 1, SU Jin Hua 1, CAI Ke xia 1, FU Yong gui 2, LI Li 2 (1. Cancer Res. Centr. of Life Science College, Xiamen Univ., Xiamen 361005, China; 2. Dept. of Biology of Life Science College, Xiamen Univ., Xiamen 361005, China);Differentiation of Human Gastric Cancer MGC 803 Cell Induced by Natural Antioxidant Isoverbascoside[J];Journal of Xiamen University(Natural Science);2001-04
6 Liu Yaxian, Li Jijun, Fu Xiaomei, et al (The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011);Experimental Study on Induction of Apoptosis by Qige Fang in Leucocythemia Cell Line K562[J];Chinese Journal of Information on TCM;2003-10
7 XU Yi, Lu Bin, DING Zhishan, et al. Department of Gastroenterology, Zhejiang Hospital of Traditional Chinese Medicine, Hangzhou 310006, China;The extract of common turmeric induces apoptosis of gastric carcinoma cell line SGC-7901[J];Zhejiang Medical Journal;2004-07
8 Wu Min Yao Baotai ~1Shandong University of TCM and Pharmacy,Jinan 250014 ~2The Hospital Affiliated to Shandong University of TCM and Pharmacy Mao Shuzhang;Advances in TCM Treatment of Gastric Cancer and Studies on the Apoptosis[J];中医杂志(英文版);2002-04
9 SHI Wen-rong,LIU Yan(Department of Integrated Traditional Chinese and Western Medicine,Fujian College of Traditional Chinese Medicine,Fuzhou 350108,Fujian,China);The Photodynamic Research in Apoptosis Induced by Curcumin on Human Gastric Cancer of BGC-823 Cells[J];Chinese Archives of Traditional Chinese Medicine;2009-09
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Li Deling;Wang Huixin;Zhou Tingchong (Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850,China).;Methods for Detecting Programmed Cell Death.[J];PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS;1996-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Li Jin Quan1,Chen Rui Chuan2,Cai Ke Xia2,Ye Zhi Yun11.Department of Biology,2. Cancer Research Center,Life Science School of Xiamen University, Xiamen, Fujian, 361005, P.R.China;Apoptosis of Human Gastric Cancer Cell Induced by Photochemical Riboflavin[J];Chinese Journal of Cancer;2003-03
2 LI Jian ming 1, YANG He ping 1,LIU Song qing 2 (1 Department of Pulmonology, Southwest Hospital, the Third Military Medical University; 2 Department of Medicine, Southwest Hospital, the Third Military Medical University, Chonqing, 400038, Chi;A morphologic investigation on apoptosis of endothelia cells induced by bisdemethoxycurcumin[J];Chongqing Medical Journal;2002-09
3 XU Qing 1, GAO Yong 1, WANG Jie Jun 1, ZHU Chang Li 1, WANG Bing 1, GUO Jing 1, BAO Hong Tao 2 (1.Department of Oncology, Changzheng Hospital, Second Military Medical University, Shanghai 200003,China;2.Department of Medical Affair;Effects of hydroxyl camptothecinum on proliferation and apoptosis of human pancreatic cancer cell line[J];Academic Journal of Second Military Medical University;2000-08
4 WANG Jin, YIN Jun-qiang, SHEN Jing-nan, JIA Qiang, HUANG Gang, JIN Song, ZOU Chang-ye Department of Musculoskeletal Oncology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China;In vitro screening of 32 traditional Chinese herbal extracts against U_2OS human osteosarcoma cells[J];Journal of Southern Medical University;2006-09
5 Xu Ershu, Xu Qing, Wang Jiejun, et al. Department of Digestion, People's Hospital, Xinchang County, Zhejiang, 312500;Inhibition of hepatoma cell line SMMC-7721 and induction of its apoptosis by hydroxycamptothecine[J];Journal of Clinical Hepatology;2003-03
6 SHI Wen-rong1,ZHANG Zhen-lin2,LIU Yan1(1.Department of Integrated Traditional Chinese and Western Medicine,Fujian College of Traditional Chinese Medicine,Fuzhou 350108,China);Effect of illumination on curcumine-induced apoptosis in human breast cancer(MCF-7) cells[J];Journal of Guangdong Medical College;2009-02
7 WEI Hong (Department of Biology and Food Engineering,Harbin College,Harbin 150001,China);Plain inhibition on the tumour of animal used as test of the curcumin[J];Journal of Science of Teachers College and University;2004-02
8 ;Progress in Relationship between Apoptosis and Traditional Chinese Medicine[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;2001-09
9 XU Zhong-xi1,WANG Kun-bo2(1.College of Food Science and Technology,Hunan Agricultural University,Changsha 410128,China;2.Hunan Provincial Engineering Research Center for Natural Products,Changsha 410128,China);Analysis of Curcumin by High Performance Thin-Layer Chromatoraphy(HPTLC)[J];Food Science;2004-06
10 CHEN Rui-chuan1,MA Shen- ping2 ,SU Jin- hua1,JIANG Xua- xun2 ( 1 . Cancer Research Center,Xiamen Univ.,Xiamen 36 1 0 0 5 ,China; 2 .Dept.of Biology,Xiamen Univ.,Xiamen36 1 0 0 5 ,China);Induction Human Gastric Cancer Line MGC80-3 Cell Apoptosis by Curcumin[J];JOURNAL OF XIAMEN UNIVERSITY(NATURAL SCIENCE);2000-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Zhao Zezhen\+1, Wen Denggui\+1, Wei Lizhen\+1 and Di Hailing\+2 \+1 Hebei Cancer Institute, Shijiazhuang 050011, \+2The Third Hospital Of Hebei Medical University;A STUDY ON THE MECHANISM OF ANTIMUTAGENESIS OF TURMERIC OIL[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1999-02
2 YAN Rui-qi LI Jun-li HUANG Mei-ling HUANG Xiao-yan WANG Hui-yun FENG Qi-sheng (Cancer Institute, Sun Yat-sen University of Medical Sciences. Guangzhou, 510060);PROTECTIVE EFFECT OF GLYCYRRHIZIN ON DNA REPALR DURING ITS INHIBITION ON DEN-INDUCED HEPATOCARCINOGENESIS[J];Chinese Journal of Cancer;1995-04
3 ZHOU Lin, AI Zhong li, LIU Zhi su,et al Department of General Surgery of the Second Affiliated Hospital of Hubei Medical University, Wuhan 430071, P R China;An in vitro study of effect of Kushen compound preparation on human colon cancer cell line SW480[J];CHINESE JOURNAL OF CANCER;2000-04
4 LI Jian ying*,YU Jie ping,LUO He sheng,YU Bao ping,TIAN Geng,MEI Qiao,HUANG Jie anDepartment of Gastroenterology,Peoples Hospital, Wuhan University,Wuhan 430060, P.R. China;Influence of Selective Cyclooxygenase-2 Inhibitor on Proliferation of Human Gastric Cancer Cells[J];Chinese Journal of Cancer;2002-06
5 ZHENG Li duan1, TONG Qiang song2, WU Cui huan31.Department of Pathology,Union Hospital of Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430022,P.R.China2.Department of Pediatric Surgery,Union Hospital of Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,P.R.China3.Department of Pathology,Tongji Medical Collage,Huazhong University of Science and Technology,Wuhan 430022,P.R.China;Inhibitory Effects of Curcumin on Apoptosis of Human Ovary Cancer Cell Line A2780 and Its Molecular Mechanism[J];Chinese Journal of Cancer;2002-12
6 Wo Xingde,Hong Xingqiu,Gao Chengxian,et al Molecular Medical Institution,Zhejiang College of TCM,Hangzhou(310009);Long-period Virulent Test of Curcumin[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-01
7 Wo XingdeHong XingqiuGao Chengxian Molecular Medical Institution,Zhejiang College of TCM,Hangzhou(310009);Maximum Toleration Test of Curcumin[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-02
8 CAI Yang (Applied Pharmaceutical Research Institute, Beijing Medical University 100083);STEREOCHEMISTRY OF DIFUROCUMENONE[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1997-03
9 CAI Yang(Applied Pharmaceutical Research Institute, Beijing Medical University, Beijing 100083);A NEW SESQUITERPENE COMPOUND —— CURCUMAFURANOL[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1998-01
10 SONG Shumei, WU jian, SHOU Chengchao (School of Oncology, Beijing Medical University, Beijing 100034);PREPARATION AND IDENTIFICATION OF MONOCLONAL ANTIBODIES AGAINST HUMAN VASCULAR ENDOTHELIAL CELL GROWTH FACTOR RECEPTOR[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1998-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 HU Zhong -ze,WANG Li -ke,YANG Jui -feng,TAN Zhi -jing, ZHANG Yuan -yuan (Department of Animal Science,Anhui Technical Teachers College, Fengyang 233100,China);Effect of Curcumin on Activity of Antioxidase and Contents of NO in Mice[J];Journal of Anhui Technical Teachers College;2004-06
2 ;and Engineering,Central South University of Forestry and Technology, Zhuzhou 412006, China )[J];China Journal of Traditional Chinese Medicine and Pharmacy;2009-03
3 WU Qiu-ling,CHEN Yan,ZHANG Chun,HE Jing.Institute of Hematology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Modulatory effect of curcumin on the adhesion and migration of Raji cells[J];Journal of Chinese Physician;2006-12
4 LIU Cheng-lun~(1,2), LI Le~(1), DENG Xin-hua~(1), QIAN Ying~(1) (1.Department of Applied Chemistry, Chongqing University, Chongqing 400030,China; isaster Control Engineering Under the State of Ministry of Education, Chongqing University, Chongqing 400030,China);Purification of Curcuma Oil With the Ginger Residue[J];Journal of Chongqing University(Natural Science Edition);2004-06
5 SHI Wen-rong1,ZHANG Zhen-lin2,LIU Yan1(1.Department of Integrated Traditional Chinese and Western Medicine,Fujian College of Traditional Chinese Medicine,Fuzhou 350108,China);Effect of illumination on curcumine-induced apoptosis in human breast cancer(MCF-7) cells[J];Journal of Guangdong Medical College;2009-02
6 CHEN Fu-bei,HUANG Chu-sheng,LIU Hong-xing(Department of Chemistry,Guangxi Teachers Education University,Nanning 530001,China);Review on Curcuminoids Separated from the Curcuma Genus[J];Journal of Guangxi Teachers Education University(Natural Science Edition);2007-02
7 SUN Zhou-liang,WANG Kun,LIN Xin-hua(1.Department of Pharmacy,The first Hospital of Xiamen Affiliated to Fujian Medical Universtiy,Xiamen 361003,China;2.Department of Pharmaceutical Analysis of the Fujian Medical University,Fuzhou 350004,China);Synthesis and character of Curcumin prodrugs bonded with PEG[J];Strait Pharmaceutical Journal;2008-12
8 LI Jing,LI Jing-Yin*,GUO Yu-Feng,WANG Wei-Xiao,LI Zi-Cheng (Department of Chemistry,Hebei University of Science and Technology,Shijiazhuang Hebei 050018,China);Research on electrochemical behaviors of the curcumin on the glassy carbon electrode[J];Journal of the Hebei Academy of Sciences;2006-04
9 ZHAO Yun-liu1,GAO Zhi1,XU Chuan-shan2(1.Department of Stomatology,Second Hospital of Chongqing Medical University,Chongqing 400010,China;2.Department of Laser center,Second Hospital of Chongqing Medical University ,Chongqing 400010,China);Effects of TMPyP4-PDT on human tongue carcinoma Tca8113 cells in vitro[J];Laser Journal;2008-04
10 ZHANG Yan-Qiang,LI Xiang-Zhou,ZHOU Wen-Wen(Central South University of Forestry & Technology,Changsha 410004,Hunan,China);Research Progress on Extractive and Detection Techniques of Curcumin[J];Nonwood Forest Research;2006-02
China Proceedings of conference Full-text Database 1 Hits
1 Yah Yong-gang Pei Jin Wan De-guang (College of pharmacy ChengDu Traditional Chinese Medicine University,Chengdu 610075,China);Study on the GC-MS Analysis of Fat-soluble Constituents of Semen persicae[A];[C];2007
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved