Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《CHINESE JOURNAL OF CANCER》 2000-08
Add to Favorite Get Latest Update

Induced differentiation of human lung adenocarcinoma cells by cinnamic acid

WANG Tao1*, JIN Ge2, WANG Shu mei1, et al 1 Department of Respiratory Medicine, the First Affiliated Hospital, Henan Medical University, Zhengzhou 450052, P R China 2 The School of Basic Medical Sciences, Henan Medical University, Zhengzhou 450052,  
Objective: To investigate the effect of cinnamic acid (CINN) on differentiation induction of a human lung adenocarcinoma cell subline (A549) Methods: A549 cells were treated with CINN in vitro The proliferation rate, mitotic index, colony forming ability in semisolid agar culture were tested The cell cycle was detected by flow cytometry(FCM) Results: CINN treatment could markedly inhibit proliferation and mitosis(P0 05), reduce colony forming rate (P0 05) CINN may inhibit DNA synthesis and mitosis of A549 cells, and arrest the cells in the G1/G0 phase Conclusion: This study indicated that CINN could induce the reversion of malignancy of A549 cells and provided experimental data for potential use of CINN in cancer treatment
【CateGory Index】: R734.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 8 Hits
1 CAO Yong,MENG Jin-cheng,XIA Qing-hua,MENG Hua,CHEN Lu,XU Lin-li,LI Liang(Department of TCM,Medical College of Jinan University,Guangdong 510632);Effect of Jianpibushenjiedu Formula on mice Lewis lung carcinoma and cell cycle of A549 lung carcinoma cells[J];Journal of Beijing University of Traditional Chinese Medicine;2009-01
2 DUAN Zhifang,FU Li(Department of Biology,Zhaoqing University,Guangdong Zhaoqing 526061,China);Synthesis of Substituted Cinnamoyl Hydrazide Compounds from Phase-transfering Catalysis[J];Journal of Zhaoqing University;2006-02
3 YAN Hua1 YANG Jian-Guo2,* LIANG Hua-Ding1 PAN Fu-You1 ZHAO Song-Lin1 LI Jing-Jing1 (1School of Pharmaceutical and Chemical Engineering, Taizhou University, Linhai 317000, Zhejiang Province, P. R. China; 2Office of Assets Administration, Taizhou University, Linhai 317000, Zhejiang Province, P. R. China);Interaction between Cinnamic Acid and Bovine Serum Albumin and the Influence of Alcohol[J];Acta Physico-Chimica Sinica;2008-03
4 Song-Lin Shi, Guo-Hong Wang, Qi-Fu Li, Zong-Yuan Ma, Chang-Jian Lin1, Zhen-Li Zhao(Key Laboratory of Ministry of Education for Cell Biology & Tumor cell Engineering, School of Life Sciences, Xiamen University, Xiamen 361005, China;1 State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China);The Effects of the Combination of Ginsenoside Rg1,Cinnamic Acid and TanshinoneII A on the Proliferation and Genes Expression of MG-63 Cell[J];Chinese Journal of Cell Biology;2008-06
5 WANG Gou-hong1,TIAN Yu-ling2,SHI He-xin1,LI Qi-fu~1* (1.Laboratory of Cell Biology,School of Life Sciences,Xiamen University,Xiamen 361005,China; 2.Shenzhen Municipal Futian Hospital,Digestant Medicine,Shenzhen 518033,China);Effects of Ursodeoxycholic Acid and Retinoic Acid on the Cell Cycle and Differentiation of Human Osteosarcoma MG-63 Cells[J];Journal of Xiamen University(Natural Science);2005-S1
6 CI Lei,TANG Xing and HE Zhong -gui (Division of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016);HPLC Determination of Cinnamic Acid in Human Plasma[J];Chinese Journal of Pharmaceutical Analysis;2004-01
7 Huang Guilin, Chen Xiaodong, Xiao Chun, Yan Yunbiao(Jiangxi College of Traditional Chinese Medicine, Nanchang, Jiangxi, China 330006;98 Grade Undergraduate Student,Jiangxi College of Traditional Chinese Medicine);The Inhibitory Effect of Germanium Cinnamateon Cervix Cancer No. 14 in Mice[J];China Pharmaceuticals;2002-04
8 Cao Yong1, Zhang Dan2, Zheng Guangjuan2, Tang Yong1, Zhang Jing2 (1.Medical college, Jinan University, Guangzhou 510632;2.Shandong University of TCM, Jinan 250014);Study on Antitumor and Synergy Effect of “Bushen Huayu Jiedu Formula” on Mice Hepatocarcinoma H_(22)[J];Journal of Chinese Medicinal Materials;2004-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Yu, WANG Bao - gui, ZHANG Gui - ying, et al ( 1. College of Preventive Medicine, Jilin University, Changchun 130021, China; 2. Leader Ward of The First Hospital, Jilin University , Changchun 130021, China);Study of Anti-tumor and Mechanism of Organogermanium Poly-derivatinmves[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-01
2 Lu Xiaoguang,Zhan Libin * (Dalian Raiway Hospital; * Second Clinical College,Dalian Medical Univ.);Changes of blood lipid and SOD,MDA of ratsmodel with simple obesity[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1997-03
3 LUO Jin-yong , LI Lin, YIN Yi-bing (Department of Diagnosis Laboratory,Chongqing University of Medical Science,Chongqing 400016,China);The effect of quercetin on proliferation and apoptosis of A549 lung cancer cell[J];Chongqing Medical Journal;2005-04
4 XU Qing Lei, WU Hai Shan, ZHOU Wei Jiang, ZHAO Ding Lin (Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai 200003,China) [;Preparation and test of type Ⅰ collagen-glycosaminoglycan (GAG) template[J];Academic Journal of Second Military Medical University;2001-04
5 Guan Liren; Yang Yuanqing; Shen Binggui; Chai Junjie Ren Haoyuan; Xu Yongxiang; Zuo Xinping; Wu Jiatong; Deng Linqi(1.Institute of Parasitic Diseases,Chinese Academy of Preventive Medicine,Shanghai 200025;2.Xinjiang Institute for Endemic Disease Control a;Study on Biology of Leishmania from Cases of Cutaneous Leishmaniasis in Karamay of Xinjiang[J];ENDEMIC DISEASES BULLETIN (CHINA);1996-03
6 LUO Hai-Bin1, QI Wei21Department of Internal Medicine, Affiliated Hospital, Peking University, Beijing 100871, China, 2Department of Surgery, PLA 520 Hospital, Mianyang 621000, China;Effects of Allium fistulosum L.oil on in vitro culture of gastric cancer cell line[J];Journal of the Fourth Military Medical University;2007-19
7 LEI Suwen1 WANG Jufang2 SU Xu1 ZHAO Jing2 LI Wenjian2 1(National Institute for Radiological Protection and Nuclear Safety, Chinese Center for Disease Control and Prevention, Beijing 100088) (Institute of Cold and Arid Environment and Engineering,Chinese Academy of Sciences, Lanzhou 730000 );Induction of DNA double-strand breaks in hepatoma cell SMMC-7721 by accelerated carbon ion~(12)C~(6+)[J];Journal of Radiation Research and Radiation Processing;2004-03
8 Huang Dejuan (Department of Biology,Fuzhou Teachers College, Linchuan Jiangxi 344000);Elementary Talking about the Heredity Diseases Cure[J];JOURNAL OF FUZHOU TEACHERS COLLEGE;2000-02
9 Li Xinyou , Liu Miao , Wang Yi, et al. Department of Orthopedics of First Hospital of Xi'an JiaoTong University , 710061;Molecular Cloning and Sequence Analysis of Full - Length cDNA Encoding Human Bone Morphogenetic Protein - 7[J];The Journal of Bone and Joint Injury;2003-09
10 Gao Jie, Jiang Guofeng1, Shi Yuxiu2 (College of Stomatology, China Medical University; 1Dental Clinic of Tiedong, Anshan; 2Department of Histology and Embryology, China Medical University, Shenyang 110001, China);〔;IMMUNOHISTOCHEMICAL STUDY OF VIMENTIN IN AMELOBLASTS OF RAT TOOTH GERMS[J];Chinese Journal of Histochemistry and Cytochemistry;2003-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 SHAN Bao_en,SI Chong_yang,ZHANG Jin_zhong,et al (Research center,The Fourth Hospital of Hebei Medical University,Shijiazhuang050011,China);The Isolation of Anti-tumor Component of Acanthopanax Gracilistylus[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-04
2 WANG Ping1,ZHANG Qing2,WANG Zu-yi2,CHENG Ze-nong1,YU Dong-hong1,WU Shi-wu1(1.Department of Pathology,Bengbu Medical College,Bengbu 233030,Anhui;2.Central Laboratory,Affiliated Hospital of Bengbu Medical College,Bengbu 230004,Anhui,China);Expression of FHIT and p16 in Non-small Cell Lung Cancers[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-03
3 Xu Du Juan, Chen Ming Zhu (Institute of Clinical Pharmacology , Anhui Medical University ,Hefei 230032);Effect of astragalus polysaccharide on immunologic function in mice[J];Anhui Medical and Pharmaceutical Journal;2003-06
4 CAI Sheng rong,FANG Zhi bin,HUANG Kai quan,WANG Yuan xun (Department of Integrated Traditional and Western Medicine, Anhui College of Traditional Chinese Medicine, Anhui Heifei 230038, China);Research on Relativity between Hemorrheology Indexes and the Levels of Endothelin and Thromboxane B_2 in Rats with Lung Qi Deficiency Syndrome[J];Journal of Anhui Traditional Chinese Medical College;2003-05
5 WANG Lin, WEN Jian ming, ZHANG Meng, et al. Department of Pathology, Sun Yat sen University of Medical Sciences, Guangzhou 510080,P.R.China;The effect of RA and DEX on the differentiation and telomerase activity of cultured osteosarcoma cells[J];CHINESE JOURNAL OF CANCER;1999-06
6 JIANG Chao, QING Chen, MENG Ling hua, et al. Shanghai Institute of Material Medical,Chinese Academy of Sciences,Shanghai 200031,P.R.China;Inhibitory effects of China ganoderma lucid essence (CGLE) on DNA topoisomerases and its ability to induce apoptosis of K562 cells[J];CHINESE JOURNAL OF CANCER;1999-06
7 ZHOU Jun min, CAO Jian guo, LIAO Duan fang Department of Pharmacology, Hengyang Medical College, Hengyang 421001, P R China;Effects of etoposide on growth proliferation and apoptosis in human HIC/S cells[J];CHINESE JOURNAL OF CANCER;2000-04
8 ZHANG Yan, JIANG Ji kai*, LIU Xiao shan, et al Department of Clinical Biochemistry, Chongqing University of Medical Sciences, Chongqing 400016, P R China;Differentiation and apoptosis in K562 erythroleukemia cells induced by matrine[J];CHINESE JOURNAL OF CANCER;2000-08
9 ZENG Xiao li*, TU Zhi guangDepartment of Clinical Biochemistry in Chongqing University of Medical Sciences, Chongqing 400016, P R China;Total saponins of panax ginseng reverse some plasmo phenotypesin human hepatoma cell line[J];CHINESE JOURNAL OF CANCER;2000-08
10 ZHANG Chun lin1* ,LIAO Wei ming1,LI Fo bao1,et al. Department of Orthopedics,the First Affiliated Hospital, Sun Yat sen University of Medical Sciences, Guangzhou 510080, P.R.China;p21WAF1/CIP1 and PCNA expressions in human osteosarcoma and their values to assess the prognosis of the patient[J];CHINESE JOURNAL OF CANCER;2000-09
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 WANG Jia-Qing1,HOU Lin 1,ZOU Xiang-Yang2,YAO Feng1,LI Xiao-Yan11.College of Life Sciences,Liaoning Normal University,Dalian 116029,Liaoning,China2.Department of Biology,Dalian Medical University,Dalian 116027,Liaoning,China;Isolation and characterization of the albinism-related genes of DEN-1 and DEN-2 from turbot Scophthalmus maximus[J];Acta Zoologica Sinica;2007-01
2 YAO Lin,DENG Kang-yin,LUO Jia-bo College of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China;Preparation and in vitro dissolution of the solid dispersions of cinnamon oil[J];Journal of Southern Medical University;2008-01
3 REN Lei,SONG Xue-wei,MA Chen,HUANG Jia-kun,HAN Yong-ping*(College of Chemistry and Environment Protection Engineering,Southwest University for Nationalities,Chengdu 610041,China);Synthesis of glucosyl esters of cinnamic acid[J];Chemical Research and Application;2007-11
4 MAO Hui,CAI Bing-feng,ZHAO Bo,LI Li,SHEN Jian(Jiangsu Key Laboratory of Biofunctional Materials,College of Chemistry and Environmental Science,Nanjing Normal University,Nanjing 210097,China);Molecule simulation and spectroscopic studies of interaction between 5-nitro-1H-indole-2-acid and bovine hemoglobin[J];Chemical Research and Application;2009-05
5 LI Qi-fu~(1),WANG Guo-hong~1,SHI Song-lin~(1,2),MA Zong-yuan~1,LIN Chang-jian~2,JING Guang-jun~1(1.Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering,School of Life Sciences,Xiamen University,Fujian Xiamen 361005,China; 2.State Key Laboratory of Physical Chemistry of Solid Surfaces,Department of Chemistry,College of Chemistry and Chemical Engineering,Xiamen University,Fujian Xiamen 361005,China);Effects of the combination of ginsenoside Rg1,cinnamic acid and tanshinone ⅡA on the morphology and terminal differentiation of MG-63 cells in vitro[J];Acta Anatomica Sinica;2009-01
6 HU Jun,SHI Ren-bing~#,ZHANG Yuan-hu,LIU Bin,DONG Yu(Beijing University of Chinese Medicine,Beijing 100102);Study on chemical compositions in the spikes of Schizonepetae tenuifolia Briq.[J];Journal of Beijing University of Traditional Chinese Medicine;2006-01
7 CHENG Cha-qun1,WEI Yan-hua1,TAN Xiu-fen1,ZENG Rui2 ( 1. Affiliated Hospital of Fangcun Third Branch Guangzhou University of Chinese Medicine,Guangzhou,Guangdong,510045 P. R. China; 2. Ethnic Pharmaceutical of Southwest University for Nationalities,Chengdu,Sichuan,610041 P. R. China);Determination of cinnamaldehyde and cinnamic acid in Cinnamon formula granule by HPLC[J];West China Journal of Pharmaceutical Sciences;2009-06
8 ZHANG Xiao-chun1,ZHOU Shu-hua1,ZOU Li-min2,CHEN Cai-fen1(1.School of Medicine,Jinggangshan University;2.School of Physical Education,Jinggangshan University,Ji′an 343000,China);The role of organic germanium in medicine[J];Journal of Jinggangshan University;2009-10
9 PENG Xueping, WANG Huajun, WANG Chuenhui, ZHANG Xue, YANG Yali (Department of Food & Biological Engineering, Zhengzhou University of Light Industry, Henan Zhengzhou, 450002 China);Studies on the Application of Cinnamon Extracts in Chilled Meat Preservation[J];Meat Research;2008-12
10 WANG Hai-yan1,2 DING Zhen-feng3 LANG Lang1 YU Lei1 JI Chen-feng1 LI Wen-lan11.Life Science and Environmental Science Research Center,Harbin University of Commerce2.Engineering Research Center of Natural Anticancer Drugs,Ministry of Educatuion3.Heilongjiang Vocational Institute of Ecological Engineering;Study on Influencing Factors of Percutaneous Absorption of Cinnamic Acid[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2008-05
China Proceedings of conference Full-text Database 2 Hits
1 WANG Hai-yan JI Yu-bin LI Wen-lan HU Zheng-ting YU Ying-Ying(Center of Research on Life Sciences and Environmental Sciences,Harbin University of Commerce,Harbin China 150076,;Engineering research center of natural anticancer drugs,ministry of educatuion,Harbin China 150076);Study on influencing factors of percutaneous absorption of cinnamic acid[A];[C];2008
2 Li Wenlan1,2,YU Yingying1,2,Ji Yubin1,2,Ren Xiaolei 1,2,XU Dong1,2(1.Center of Research and Development on Life Sciences and Environmental Sciences,Harbin University of Commerce,Harbin 150076,China,2.Engineering Research Center of Natural Anticancer Drugs,Ministry of Education,Harbin University of Commerce,Harbin 150076,China);Study on Relationship between Metabolism of Cinnamic Acid and Cytochrome P450[A];[C];2008
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved