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《Chinese Journal of Cancer》 2004-06
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Sonographically Guided Percutaneous “Air-Cooled” Microwave Coagulat ion in Live Pig Liver:An Experimental Study

Zheng Yun,Li Jin-Qing,Zhang Ya-Qi,Chen Min-Shan,Zhang Yao-Jun,Huang W an Department of Hepatobiliary Tumor,Cancer Center,Sun Yat-sen University,Guangzhou,Guangdong,510060,P.R.China  
BACKGROUND OBJECTIVE: Sonographically guided percutaneous microwa ve coagulation therapy has been widely used as an effective minimal invasive the rapy for small liver cancer. However, high temperature of the shaft of the elect rode blocks the advance of microwave coagulation in the treatment of liver cance r. The present study was conducted to investigate the prospect of the newly deve loped microwave coagulation equipment with “air-cooled”electrode in the treat ment of liver cancer. METHODS: Six Pigs underwent hepatic coagulation at 60 W fo r 10 minutes, 60 W for 20 minutes, 80 W for 10 minutes, and 80 W for 20 minutes under US-guided percutaneous microwave coagulation using the “air-cooled”mic rowave coagulation equipment-ECO-100 Advanced Type. RESULTS: The experiment sh owed that the lesion size of microwave coagulation in single irradiation could b e significantly enlarged when increasing the power output and exposure duration without the worry of high temperature of the shaft of the electrode. Microwave c oagulation using the “air-cooled”electrode produced a necrosis volume of 4.0 cm×4.3 cm at 80 W for 10 minutes, 4.7 cm×5.2 cm at 80 W for 20 minutes. The “ air-cooled”microwave coagulation did not leave a trail in the coagulation area . CONCLUSION: The technique of “air-cooled”electrode can decrease the tempera ture of the shaft of the electrode. The effectiveness could be improved through increasing the power output and exposure duration.
【CateGory Index】: R735.7
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