Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Cancer》 2007-09
Add to Favorite Get Latest Update

Research Progress on the Relationship between Nutrition and Cancer Epigenetics——Histone Modification Mechanisms

TENG Li-Juan, LI KeDepartment of Molecular Epidemiology, Medical College, Shantou University, Shantou, Guangdong, 515041, P. R. China  
Epigenetics is the study of processes that establish metastable ( that is, somatically heritable) state of gene expression without altering the sequence. Epigenetic information includes nucleosome remodeling; genomic imprinting; X chromosome inactivation; DNA methylation; chromosome protein changes, including histone modification [acetylation, methylation, phosphorylation, poly (ADP-ribosylation) , lysine (K) residue biotinylation, and so on] , histone variants exchange, non-histone changes; and uncoding RNA-regulating transcription. Carcinogenesis springs from the combined forces of both genetic and epigenetic events. Although the importance of genetic mutations in cancer has long been recognized , the role of epigenetic modification has been suggested more recently. Nutrients play essential roles in human health, and may modify cancer risk. This article sumed up recent researches on histone modification mechanism, approached the molecular mechanism during cancer initiation and development and the application in cancer prevention and treatment in histone modification level respectively, and summarized the relationship between diet nutrition and cancer epigenetic mechanism in histone modification level.
【Fund】: 日本文部省科学技术优先项目~~
【CateGory Index】: R730.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 2 Hits
1 Pu-Yuan Wu,1,2 Yi-Mei Fan1,2 and Ya-Ping Wang1,2 1. Department of Medical Genetics, Medical School, Nanjing University, Nanjing, Jiangsu 210093, P. R. China 2. Jiangsu Key Laboratory of Molecular Medicine, Nanjing, Jiangsu 210093, P. R. China;Germ-line epimutations and human cancer[J];Chinese Journal of Cancer;2009-12
2 Lü Fang,SU You-hong, ZHANG Fu-chun,LI Jiang-wei (National Key Laboratory of Xinjiang Biology Resources and Genetic Engineering,College of Life Science and Technology,Xinjiang University,Urumqi 830046,China);Survey on active components in plant with antitumor activity by epigenetic modulation[J];Chinese Traditional and Herbal Drugs;2008-10
Chinese Journal Full-text Database 1 Hits
1 ZHANG Yong-Biao, CHU Jia-You(Department of Genetics, Institute of Medical Biology, Peking Union Medical College, Kunming 650118, China);Progress of Research on Epigenetic and Human Disease[J];Hereditas(Beijing);2005-03
Chinese Journal Full-text Database 10 Hits
1 ZHANG Li-Xia1, PAN Shi-Yang1, CHEN Dan1, XIE Er-Fu1, GAO Li1, SHU Yong-Qian2, LU Zu-Hong3, CHENG Lu3, YANG Di4, ZHANG Ji-Nan4 1. Center of Clinical Laboratory, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China 2. Department of Oncology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China 3. Department of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, P. R. China 4. Department of Cardiovascular Disease, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China;Effect of Adenomatous Polyposis Coli(APC) Promoter Methylation on Gene Transcription in Lung Cancer Cell Lines[J];Chinese Journal of Cancer;2007-06
2 Hong-Li Li,1 Wei-Dong Zhang,2 Wen-Tong Li2 and Chong-Gao Yin31.Medicine Research Experiment Center of Science Research, Weifang Medical College, Weifang, Shandong, 261042, P.R.China 2.Department of Pathology, Weifang Medical College, Weifang, Shandong, 261042, P.R.China 3.Department of Nursing, Weifang Medical College, Weifang, Shandong, 261042, P.R.China;Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2[J];Chinese Journal of Cancer;2009-09
3 YANG Hong-dan,GAO Shi-yong(Cneter of Research and Development on Life Scineces and Environmental Sciences,Harbin University of Comerce,Harbin 150076,China);Relationship between DNA methylation aberration and human tumor[J];Journal of Harbin University of Commerce(Natural Sciences Edition);2007-04
4 WANG Zheng-chao,PAN Xiao-yan,PANG Xun-sheng (1.College of Animal Science and Technology,Nanjing Agricultural University, Nanjing 210095,China; 2.Anhui College of Science and Technology,Bengbu 233100,China);Dosage Compensation of Early Embryo and Its Effect on the Development of Mammals[J];Acta Ecologiae Animalis Domastici;2006-06
5 TENG Li-juan,ZHANG Chang-song reviewing,LI Ke checking(Department of Molecular Epidemiology,Shantou University Medical College,Shantou 515041,Guangdong,China);Relationship of nutrition with cancer and its epigenetic DNA methylation mechanism[J];Journal of Medical Postgraduates;2008-01
6 ZHAO Ying~1,ZHOU Yu-xun~2,LI Kai~2,XIAO Jun-hua~2(1.School of Bioengineering,East China University of Science and Technology,Shanghai 200237,China;2.Institute of Biology Science and Technology,Donghua University,Shanghai 201620,China);Relationship between LHβ,FSHβ Genes and Central Precocious Puberty in Chinese Girls Based on the Polymorphisms in the 5′-Flanking Regions[J];Journal of East China University of Science and Technology(Natural Science Edition);2009-04
7 PENG Guo,DAI Dong-qiu Department of Oncology Surgery,First Affiliated Hospital,China Medical University,Shenyang 110001,P.R.China;Development in research on histone acetylation and methylation in alimentary canal neoplasms[J];Chinese Journal of Cancer Prevention and Treatment;2007-24
8 GU Ting-ting~(1,2),ZHANG Zhong-ming~1,ZHENG Peng-sheng~(1,2)(1.Department of Gynecology and Obstetrics,The First Affiliated Hospital of Medical College,Xi'an Jiaotong University,Shaanxi Xi'an 710061,China;2.Key Laboratory of Environment and Genes Related to Diseases,Medical College,Xi'an Jiaotong University,Ministry of Education,Shaanxi Xi'an 710061,China);Review and evaluation of methodology of research on DNA methylation[J];Chinese Journal of Maternal and Child Health Research;2006-06
9 WANG Xia,QIN Xiuli(Jilin Agricultural Science and Technology College Department of Bioengineering,Jilin 132101,China);On the Producing,Mechanism and Biology Meaning of Epigenetics[J];Journal of Jilin Agricultural Science and Technology College;2008-04
10 Xin-Jiang Zhu, Dong-Qiu Dai, Department of Oncology Surgery, the First Affi liated Hospital of China Medical Uni- versity, Shenyang 110001, Liaoning Province, China;Epigenetic modif ication and gastrointestinal tumor[J];World Chinese Journal of Digestology;2006-34
Chinese Journal Full-text Database 4 Hits
1 YUAN Yun fei 1, LI Jin qing1, YANG Zu li2, WANG Jian ping2*1. Tumor Hospital, Sun Yat sen University, Guangzhou 510060, P.R.China.2. The First Affiliated Hospital, Sun Yat sen University 510089, P.R.China;The Roles of DNA Methylation in Human Neoplasms[J];Chinese Journal of Cancer;2002-11
2 LI Jian-Hua1, SHI Xian-Zhe2, LIU Min1, WANG Yan1, YU Zhi-Hong1, XU Guo-Wang2, LU Shen11. Laboratory of Molecular Biology, Experimental Center,The Second Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, 116027, P.R.China2. National Chromatographic Research and Analysis Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences,Dalian, Liaoning, 116011, P.R.China;Methylation of hMLH1 Gene Promoter in Gastric Carcinoma with Microsatellite Instability[J];Chinese Journal of Cancer;2005-03
3 ZHANG Qian1,JIN Jie1,TAO Qian2 1. Department of Urology,Institute of Urology,The First Hospital,Peking University,Beijing,100034,P. R. China 2. Cancer Epigenetics Laboratory,State Key Laboratory in Oncology in South China,Sir YK Pao Center for Cancer,Department of Clinical Oncology,Hong Kong Cancer Institute and Li Ka Shing Institute of Health Sciences,Chinese University of Hong Kong,Hong Kong;Aberrant Methylation of Tumor Suppressor Genes in Renal Cell Carcinoma[J];Chinese Journal of Cancer;2007-11
4 WANG Xi,ZHU Wei-Guo Department of Biochemistry and Molecular Biology,Peking University,Health Science Center,Beijing,100191 P.R.China;Advances in Histone Methyltransferases and Histone Demethylases[J];Chinese Journal of Cancer;2008-10
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved