Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Cancer》 2009-01
Add to Favorite Get Latest Update

Efficacy of argon-helium cryosurgical ablation on primary hepatocellular carcinoma: a pilot clinical study

Lin Zhou,1,2 Yong-Ping Yang,2 Yong-Yi Feng,2 Yin-Ying Lu,2 Chun-Ping Wang,2 Xin-Zhen Wang,2 Lin-Jing An,2 Xin Zhang2 and Fu-Sheng Wang21. PLA Postgraduate Medical School, Beijing, 100853, P. R. China 2. Liver Carcinoma Therapy Research Center PLA 302 Hospital, Beijing, 100039, P. R. China  
Background and Objective: Recent years, great progression has been made in treating primary hepatocellular carcinoma (HCC) with argon- helium cryosurgical ablation. This study was to evaluate its efficacy on unresectable primary HCC. Methods: A total of 124 primary HCC patients were divided into early stage, middle stage and advanced stage groups according to BCLC staging classification. Clinical symptoms, tumor size, serum level of alpha-fetoprotein (AFP), complications, and survival time were analyzed. Results: After cryoablation of the tumors, serum level of AFP was reduced in 76 (82.6%) patients, 205 (92.3%) of the 222 tumor lesions were diminished or unchanged. Till April, 2008, 14 patients survived and 110 died. The median survival time was 31.25 months in early stage group, 17.41 months in middle stage group and 6.82 months in advanced stage group. Conclusion: For the patients with unresectable HCC, argon-helium cryosurgical ablation has the advantages of few complications and certain efficacy.
【CateGory Index】: R735.7
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 8 Hits
1 Yang Yongping 302 Hospital of PLA,Beijing 100039,China;Current status and progress in non-resection therapies for hepatocellular carcinoma[J];Infectious Disease Information;2009-02
2 LU Yin-ying,WANG Chun-ping,QU Jian-hui,ZHOU Lin,CHANG Xiu-juan,BAI Wen-lin,CHEN Yan,AN Lin-jing,ZENG Zhen,YANG Yong-ping* Clinical Research Center of Hepatocarcinoma,No.302 Hospital of PLA,Beijing 100039,China;Liver microvessel density in evaluating therapeutic effect of sorafenib combined with argon-helium cryoablation in treatment of advanced hepatocellular carcinoma[J];Academic Journal of Second Military Medical University;2010-11
3 LEI Jun-qiang1,CHAI Wen-xiao2(1.Department of Radiology,the First Hospital,Lanzhou University,Lanzhou 730000,China; 2.Department of Interventional-Radiology,Gansu Provincial People's Hospital,Lanzhou 730000,China);The Status Quo of Interventional Therapies for Hepatic Carcinoma[J];Journal of Gansu Sciences;2011-01
4 Bin Wu,Yue-Yong Xiao, Xiao Zhang, Ai-Lian Zhang, Hong-Jun Li and Deng-Fa Gao Department of Radiology, Chinese PLA General Hospital, Beijing, 100853, China;Magnetic resonance imaging-guided percutaneous cryoablation of hepatocellular carcinoma in special regions[J];国际肝胆胰疾病杂志(英文版);2010-04
5 ;Progress in non-vascular intervention for hepatocellular carcinoma[J];International Journal of Medical Radiology;2011-04
6 LU Yin-ying,CHANG Xiu-juan,ZHOU Lin,WANG Chun-ping,ZENG Zhen,CHEN Yan,QU Jian-hui, WU Yu,BAI Wen-lin,YANG Yong-ping .Clinical Research Center of Hepatocarcinoma,302Hospital of PLA,Beijing 100039,China;A study of combining sorafenib with cryoablation for the treatment of hepatitis B-related hepatocellular carcinoma[J];Medical Journal of Chinese People's Liberation Army;2010-12
7 LU Yin-ying,CHANG Xiu-juan,WANG Chun-ping,ZHOU Lin,CHEN Yan,WU Yu,QU Jian-hui,ZENG Zhen,BAI Wen-lin,YANG Yong-ping(Therapeutic Research Center of Hepatocarcinoma,302 Hospital of PLA,Beijing 100039,China);Therapeutic effects and prognostic analysis of Sorafenib combined with Cryoablation on hepatitis B-related advanced hepatocellular carcinoma[J];China Oncology;2010-10
8 XI Zhan-guo1,LI Ke2,LI Xing-mei 3,CHEN Ye4,CHEN Mei 5 1.Department of Ultrasound,Luoyang Orthopedic-Traumatological Hospital,Luoyang 471000,China;2.Department of MRI Room,The First Affiliated Hospital,Henan University of Science and Technology,3.Center of Cryotherapy,4 Department of Oncology,5.D epartment of Ultrasound;Ar-He(argon-helium) Cryoablation Treatment for Implanted VX2 Iiver Tumor in Rabbit Model[J];Cancer Research on Prevention and Treatment;2010-11
Chinese Journal Full-text Database 4 Hits
1 ZHANG Ke-qin1, ZHANG Ji-ren1, WEI Hong-mei2 1Cancer Prevention and Treatment Center, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China; 2Oncology Center, 88 Hospital of PLA, Tai'an 271000, China;Therapeutic effects of cryoablation, radiorequency ablation, and microwave coagulation against VX2 liver cancera comparative study in rabbits[J];Journal of Southern Medical University;2007-09
2 Dong Jinling1,Ding Huiguo1,Zhao Long2,Li Xia1,Liu Binchen1,Wang Ying1(1.Beijing You'an Hospital,Capital Medical University;2.Chinese armed police force shenyang commanding college);Clinical Analysis of 396 Fatal Patients with HCC in Beijing[J];Journal of Capital Medical University;2007-04
3 WANG Zhi-ming~1, REN Zheng-gang~2~△, WANG Tian-hao~2, WANG Zheng~2, YE Tong~3, CHEN Jun~2, YE Sheng-long~2, TANG Zhao-you~2 ( ~1Department of Oncology, ~2Institute of Liver Cancer, ~3Department of Radiology, Zhongshan Hospital, Fudan University, Shanhai, 200032,China);The impact of Argon-Helium cryotherapy on metastasis of rabbit liver tumor[J];Fudan University Journal of Medical Sciences;2006-06
4 WEN Bing-ji,HU Liu-yan,SHI Zhan-ying,et al(Department of Medical Oncology,113th hospital of PLA,Ningbo,Zhejiang 345040,China);Influence of cryoablation on liver function in patieints with stage-Ⅲ/Ⅳ primary hepatic carcinoma[J];Chinese Journal of Clinical Oncology and Rehabilitation;2006-04
Chinese Journal Full-text Database 10 Hits
1 YU Hong-bao1,GE Cheng-lin2,HUANG Zong-hai1,WANG Hao3,LIU Zeng-yi2,ZHANG Ji-ren1 1Tumor Center,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China;2Tumor Hospital of Weifang City,Weifang 261041,China;3Department of Pathology,Medical College of Shandong University,Ji'nan 250001,China;Effect of targeted argon-helium cryoablation on the portal region in canine livers[J];Journal of Southern Medical University;2009-03
2 XU Jian, CAO Jian-min, LU Guang-ming.Department of Medical Imaging, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China;Evaluation of targeted argon-helium cryoablation in treating solid tumors[J];Journal of Interventional Radiology;2009-07
3 ZHENG Xiao-huan WEI You-guo ZHOU Hong-bin LIN Shao-hua,LIU Yuan-shui(1 Therapy Center of Tumor,The Qianfoshan Hospital;Jinan 250014,China);Effect of cryosurgery ablation on tumor-infiltrating lymphocytes of tumor-bearing rabbit[J];Journal of Taishan Medical College;2009-12
4 ZHOU Lin1,2,YANG Yongping2,LIU Jing3,FENG Yongyi2,LU Yinying2, WANG Chunping2,WANG Xinzhen2,AN Linjing2,ZHANG Xin2,HAO Liyan2,WANG Fusheng21.PLA Postgraduate Medical School,Beijing 100853;2.PLA 302 Hospital;3.Navy General Hospital,China;Treatment of early-stage hepatocellular carcinoma with argon-helium cryosurgical ablation system[J];Chinese Journal of Gastroenterology and Hepatology;2008-12
5 SHI De-gang, ZHANG Ji-ren;Clinical Issues of Tumor Targeted Ablation Therapy[J];Journal of Oncology;2008-07
6 Lin-Xue Qian, Hong-Tao Wei, Xiang-Dong Hu, Ultra- sound Department, Beijing Friendship Hospital Affi liated to Capital Medical University, Beijing 100050, China;Current situation and progress of local ablation therapy for hepatocellular carcinoma[J];World Chinese Journal of Digestology;2008-18
7 Jian-Gang Liu, Ji-Ren Zhang, Oncology Center, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China Hong-Zai Guan, Department of Hematology, Qingdao University Medical College, Qingdao 266021, Shandong Province, China Cheng-Lin Ge, Interventional Therapy Center, Weifang Cancer Hospital, Weifang 261041, Shandong Province, China;Effect of argon-helium cryoablation on cell apoptosis and T-cell immunity in rats subcutaneously implanted with breast cancer cells[J];World Chinese Journal of Digestology;2009-23
8 BAO Lijing,XIANG Xiaoxing,JIANG Yulan,et al.Department of Gastroenterology,Northern Jiangsu People's Hospital,Yangzhou 225001,CHINA;Analysis on prognosis factors and therapeutic efficacy of 344 patients with primary hepatic carcinoma in central district of Jiangsu province in China[J];Jiangsu Medical Journal;2010-06
9 ZHOU Lin,WANG Fu-sheng.(Postgraduate Medical School of PLA,No 9 Department of Infectious Disease,302 Hospital of PLA,Beijing 100853,China);Progress of Anti-tumor Immune Efficacy of the Therapy with Argon-helium Cryosurgical System[J];Medical Recapitulate;2008-17
10 YAO Qing-shen,QIN Jun,ZHOU Lin-rong.(Department of General Surgery,Red Cross Hospital of Yulin in Guangxi,Yulin 537000,China);Therapeutic Progress of Cryoablation for Liver Cancer by Magnetic Resonance Guidance[J];Medical Recapitulate;2009-10
Chinese Journal Full-text Database 10 Hits
1 Zeng Zhaochong1 Tang Zhaoyou2 Fan Jia2 Qin Lunxiu2 Ye Shenlong2 Zhou Jian2 Sun Huichuan2 Wang Binliang1 Wang Jianhua3 1 Department of Radiation Oncology,Zhongshan Hospital,Fudan University,Shanghai 200032,China 2 Liver Cancer Institute,Zhongshan Hospital,Fudan University,Shanghai 200032,China 3 Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China;A comparison of treatment combinations with and without radiotherapy for the hepatocellular carcinoma with portal vein and/or inferior vena cava tumor thrombus[J];Oncology Progress;2006-04
2 ZHAN Bi-hong(Department of Radiotherapy,Huaibei People's Hospital,Huaibei Anhui 235000,China);Three-dimensional conformal radiotherapy for primary hepatocellular carcinoma:Report of 35 cases[J];Journal of Bengbu Medical College;2009-02
3 YANG Chuang1,ZHANG Hong-yu2,KONG Xiao-xia2,SUN Lian-kun2,ZHENG Yu3,WANG Guang-yi1(1.Department of General Surgery,First Hospital,Jilin University,Changchun 130021,China;2.Department of Pathophysiology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China;3.Department of General Surgery,First Hospital of Haerbin City,Haerbin 150010,China);Changes of Bcl-2 and Bax on vitamin K3 induced injury in human hepatocarcinoma SMMC-7721 cells[J];Journal of Jilin University(Medicine Edition);2009-01
4 Lu Yinying,Chen Yan,Feng Yongyi 302 Hospital of PLA,Beijing 100039,China;Clinical advances in cryoablation therapy for hepatic carcinoma[J];Infectious Disease Information;2009-02
5 LEI Xiao, YU Pei-wu, ZHAO Yong-liang, SHI Yan, RAO Yun, ZENG Dong-zhu, WU Miao, ZHOU Li-xin (Department of General Surgery, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Expression and clinical significance of CD4 ~+ and CD25 ~ + regulatory T cells in patients with gastric carcinoma[J];Acta Academiae Medicinae Militaris Tertiae;2006-05
6 DANG Ya-Zheng1,YANG Jie2,FEI Jin-Xiu1,QI Tao1,CAI Yong-Sheng1,BAI Rui-Jia1,LU Wan-Ling11Cancer Center,PLA 323th Hospital,Xi'an 710054,2 PLA 1st Hospital,Lanzhou 730050,China;High-intensity focused ultrasound for treatment of portal vein tumor thrombosis:40 cases report[J];Journal of the Fourth Military Medical University;2008-22
7 ZHANG Ke-qin1, ZHANG Ji-ren1, WEI Hong-mei2 1Cancer Prevention and Treatment Center, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China; 2Oncology Center, 88 Hospital of PLA, Tai'an 271000, China;Therapeutic effects of cryoablation, radiorequency ablation, and microwave coagulation against VX2 liver cancera comparative study in rabbits[J];Journal of Southern Medical University;2007-09
8 FAN Ying-fang,FANG Chi-hua,HUANG Zong-hai,XIANG Nan,YANG Jian Department of General Surgery,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China;Intraoperative argon cryosurgery in surgical resection of advanced hepatic carcinoma:safety and efficacy[J];Journal of Southern Medical University;2008-11
9 ZHANG Zhixuan, FAN Yu, ZHOU Qinghua, WANG Yanping, MA Li, CHEN Xiaohe, ZHU Wen, YANG Xueqin, ZHAO Ying. Key Laboratory of Lung Cancer Molecular Biology of Sichuan Province, Cancer center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R.China (ZHANG Zhixuan and FAN Yu are co-first authors);Effects of polysaccharid on expression of angiogenic-related genes in human high-metastatic large cell lung cancer cell line L9981[J];Chinese Journal of Lung Cancer;2006-02
10 QIAN Guojun,CHEN Han,WU Shengpei,et al. Eastern Hopatobiliary Surgery Hospital,Second Military Medical University,Shanghai 200438,China;Percutaneous cryoablation of liver carcinoma-A report of 56 cases[J];Journal of Abdominal Surgery;2003-01
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 YAN Jun1,TAO Wen-zhao2,CHEN Wei1,LU Guo-feng3,HU Yu-xin1△(1 Department of Medical Oncology,Shanghai Jiading Central Hospital,Shanghai 201800,China; 2 Department of Pathology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China; 3 Department of Pathology,Shanghai Jiading Central Hospital,Shanghai 201800);Effect of Intratumoral Injection of Sodium Hydroxide in Inhibition of Liver Tumor Growth[J];Progress in Modern Biomedicine;2011-07
2 YAN Jun,TAO Wen-zhao,CHEN Wei,et al.Department of Medical Oncology,Shanghai Jiading Central Hospital,Shanghai,201800;Therapeutic Effects of Intratumoral Injection of Sodium Hydroxide on Growth and Metastasis of Liver Cancer in Nude Mice Models[J];The Practical Journal of Cancer;2011-01
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 WU Ji-zhou YEH Fu-sun MO Zhi-chun (Guangxi Cancer Institute China);A DETERMINATION OF THE AETIOLOGICAL FACTORS OF HEPATOCELLULAR CARCINOMA IN GUANGXI, CHINA-118pairs matched case-control study analysis by multiple conditional logistic regression model[J];Chinese Journal of Cancer;1990-01
2 Qiu Yudong,Zhang Weiwei,Wu Yafu,et al. Department of General Surgery,Drumtower Hospital,the Medical College of Nanjing University,Nanjing,210008;ABLATION OF HEPATIC CARCINOMA WITH COOL-TIP RADIOFREQUENCY(51 CASES REPORT)[J];Journal of Hepatobiliary Surgery;2001-06
3 Wu Jizhou,Su Minghua,Chen Maowei,et al.(Department of Infectious Diseases,the First Affiliated Hospital of Guangxi Medical University,Nanning,530021 China);A MATCHING CASE-CONTROL STUDY ON THE RELATIONSHIP BETWEEN HBV,HCV INFECTION AND HCC IN ENDEMIC AREA OF HCC IN GUANGXI,CHINA[J];Journal of Guangxi Medical University;2003-03
4 SHAO Guoliang, ZHOU Kangrong, WANG Jianhua,et al. Department of Radiology, The Affiliated Zhongshan Hospital, Medical College of Fudan University, Shanghai 200032, P.R.China;Improvement in Making Rabbit Model Bearing VX2 Liver Tumor for Interventional Experimental Study and CT Evaluation of the Tumor[J];JOURNAL OF CLINICAL RADILOLGY;2000-10
5 CAO Wei,WANG Zhi-min,ZHANG Hong-xin,LIANG Zhi-hui,QI Lian-jun, LI Wei-xian,NI Dai-hui(Department of Interventional Radiology,Tangdu Hospital,The Fourth Military Medical University,Xi'an 710038,China);The Study of Transplanting Methods and Growing Features of VX_2 Carcinoma in Rabbit Liver[J];Journal of Practical Radiology;2003-02
6 FANG Wen,TENG Gao-jun,HE Shi-cheng,DENG Gang,GUO Jin-he,ZHU Guang-yu,LI Guo-zhao (Department of Radiology, Zhongda Hospital, Southeast University, Nanjing 210009,China);Percutaneous cryoablation combined with TACE for liver carcinoma[J];Modern Medical Journal;2004-06
7 SONG Hua-zhi, YI Feng-tao , LIU Ying, et al (Centre of Ar-He Knife,Wuhan General Hospital,Guangzhou Military Region,Wuhan 430070,China);Clinical analysis of treatment of liver tumor with Ar-He target cryoablation[J];Chinese Journal of Clinical Oncology and Rehabilitation;2004-02
8 WANG Hong-wu,HE Sheng(Navy General Hospital,Beijing 100037,China);Percutaneous cryoablation of heptic cancer[J];Chinese Journal of Clinical Oncology and Rehabilitation;2005-01
9 QIAN Guojun, CHEN Han, WU Mengchao, et al. Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, P. R. China;Percutaneous cryoablation in combination with chemoembolization in treatment of liver malignancy: a report of 34 cases[J];Chinese Journal of Hepatobiliary Surgery;2004-08
10 FANG Chi hua, ZHONG Hong cai, CHEN Xiao wu, GAO Peng Department of Hepatobiliary Surgery, Zhujiang Hospital, the First Military Medical University, Guangzhou 510282, China Corresponding author: FANG Chi hua, E mail: fch58520@sina com;Treatment of advanced liver neoplasm by intraoperative argon super-cryosurgery system[J];Chinese Journal of General Surgery;2005-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved