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Influence of radiotherapy on the effectiveness of chemotherapy in patients with limited and extensive stages of small cell lung cancer (SCLC)

CAO Kajia,MAO Zhida, CUI Nianji, et al Department of Radiotherapy, Cancer Center, Sun Yatsen University of Medical Sciences, Guangzhoun 510060, China  
bjective: A retrospective analysis was performed to study the influence of radiotherapy on the effectiveness of chemotherapy in the patients with limited or extensive stage SCLC. Methods: Survival rates were analyzed and compared by life table and LogRank test between 61 patients with SCLC treated with chemoradiotherapy and 46 patients with chemotherapy alone. Results: The 1,3,5year survival rates of the patients with SCLC were 705%,254%,129%respectively in chemoradiotherapy group and 407%,26%,26%respectively in chemotherapy only group, showing a significant difference between the two groups (P 001). The 15year survival rates of patients with limited stage SCLC in chemoradiotherapy group were higher than those in chemotherapy group (P 0025), but there was no difference between the two groups for patients with extensive stage SCLC ( P005). Conclusion: The survival rates can be increased with chemoradiotherapy for patients with limited stage SCLC, but there was no difference for patients with extensive stage SCLC.
【CateGory Index】: R730.55,R734.2
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