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《Journal of Anhui Agricultural University》 2006-02
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Effects of age on ability of novel-object recognition in senescence-accelerated prone mouse 8

YANG Qi-gang~(1,2),CHEN Gui-hai~1(1.Department of Neurology,the Affiliated Hospital of Anhui Medical University,Hefei 230032;2.Department of Neurology,Anhui Hospital of Chinese People′s Armed Police Forces,Heifei 230041)  
The effect of age on the ability of novel-object recognition in mice was explored,the results showed that the ability of novel-object recognition in eleven-month-old senescence-accelerated prone mouse 8(SAMP8) increased in comparison to the three-and seven-month-old mouse in the novel-object recognition task.Compared to the control strain,senescence-accelerated resistant mouse 1(SAMR1) at age of 11 months,the ability of mouse 8(SAMR8) in the eleven-month-old increased,too.The results suggest that during aging,the ability of novel-object recognition in SAMP8 mice may increase.
【Fund】: 安徽省自然科学基金(03043708);; 安徽教育厅自然科学基金(2003kj191)共同资助
【CateGory Index】: R33
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【References】
Chinese Journal Full-text Database 2 Hits
1 YANG Xin1,DENG Nian-qing2,GU Xiu-ping2,ZHU De-fa1,CHEN Gui-hai3 (1.Department of Endocrinology,Anhui Geriatric Institute,the First Affiliated Hospital of Anhui Medical University,Hefei 230022;2.Research Administration Office,Anhui Medical University,Hefei 230032;3.Department of Neurology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022);Relationship between spatial cognitive impairment and the TH levels in middle-aged ICR mice[J];Journal of Anhui Agricultural University;2008-02
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【Co-references】
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1 LI Xia,YUAN Feng-lai,YUAN Li-ping,CHEN Fei-hu (School of Pharmacology,Anhui Medical University,Hefei 230032,China);Progressive research on the effect of polyunsaturated fatty acids in regulation of plasma lipids[J];Anhui Medical and Pharmaceutical Journal;2007-10
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3 XU Wen-rui1,XIONG Xiang-dong1,2,CHEN Gui-hai1(1.Department of Neurology,the Affiliated Hospital of Anhui Medical University,Hefei 230022;2.People′s Hospital of Lu′an City,Lu′an 237005);Effects of ageing on different spatial ability of learning and memory in C57BL/6 mice[J];Journal of Anhui Agricultural University;2007-01
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8 CHEN Gui-hai(Department of Neurology,the Affiliated Hospital of Anhui Medical University,Hefei 230022);Age-related impairment of learning and memory abilities in animals[J];Journal of Anhui Agricultural University;2007-03
9 WANG Chao1,JIANG Wei1,HUANG De-wu2,TAO Fei1,CHEN Gui-hai1(1.Department of Neurology,the Affiliated Hospital of Anhui Medical University,Hefei 230022;2.Experimental Animal Center,Anhui Medical University,Hefei 230032);Effects of apparatus on age-related impairement of novel-object recognition in Kunming mice[J];Journal of Anhui Agricultural University;2009-02
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【Secondary References】
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1 LIU Chun-lei1,JIA Xue-mei2,YANG Hao1,CHEN Gui-hai3,ZHU De-fa1(1.Department of Endocrinology,Anhui Geriatric Institute,the First Affiliated Hospital of Anhui Medical University,Hefei 230022;2.Laboratory of Morphology,Anhui Medical University,Hefei 230032;3.Department of Neurology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022);Changes of synaptotagmin 1 and therapeutic effect of thyroid hormone in hippocampus of the adult hypothyroid rats[J];Journal of Anhui Agricultural University;2008-04
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