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《Journal of Safety and Environment》 2005-04
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Review on biological effects of manufactured nano-materials

ZHU Xiao-shan,ZHU Lin(School of Environmental Science & Engineering, Nankai University, Tianjin 300071, China)  
The present paper aims to introduce the authors' study on the biological effects of the manufactured nano-materials on the people's life, both positive and negative. As we know, since manufactured nano-materials (MNMs) can meet diversified needs of human beings for their exclusive properties, they have been developed very fast in recent years. At present, more and more MNMs have been brought into market and given strong impact on the improvement of people's living standards. At the same time, a new problem has turned to be the focus of people's attention, that is, whether such materials may bring about harms to the Environment and people's health. As a matter of fact, some research information and data have been gained in resent years aiming to analyze the MNMs' exposures as well as their biological effects, including their toxic effect on human cells, lungs and brains. The present paper has summarized and analyzed all the above effects, in addition to their influence on their biogenetic mutatuon and bioaccumulation, along with their absorption through skin. At the same time, the physical and chemical characteristics of such materials and theirs surface modification are also analyzed as significant factors that are likely to bring about some biological effect. In addition, potential toxicological mechanism of nano-materials is also probed into by consulting the research results on Ultrafine Particles. And, finally, the vista of nanotoxicology is provided here in the paper.
【Fund】: 国家自然科学基金资助项目(30470319)
【CateGory Index】: TB383
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