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《Anqing Medical Journal》 2008-01
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Clinical effect of mild hypothermia on patients with severe brain injury

Zha zheng-jiang,Wu xia,Cheng xing-sheng.Anqing municipal Hospital,Anhui,246003  
Objective To study the effects of mild hypothermia on the patients with severe brain injury.Methods All 78 patients with severe injury(Glasgow coma scale of 8 or less on odmission)were randomly divided into the hypothermic grorp(40 cases)and the control group(38 cases).Hy pothermia was induced within 24 hours of injury.Rewarming was begun on 1~7 days(average 65.3±28.2 hours)after the rectal tamperature(RT)reached 33.0~35℃.Meantime,the vital signs intracranial pressure(ICP),blood gas values,blood electrolytes,blood oxygen pressure were measured.The rectal temperature of control patients was induced to 36.5~37.5℃,According to Glasgow Outcome Scale(GOS),the Prognosis of the patients was evalued.Results In comparison with control group,during mild hypothermia increased ICP Significantly clecreased(P0.05),The vital sign,blood gas values and blood electrolytes did not significantly change,The decreased mortality and good recovery were also found in hypothermia group.Conclusions Mild hypothermia is safe and effective for preventing brain damage of the patients with severe nead injury,which can reduce the mortality and improve the prognosis.
【CateGory Index】: R651.15
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