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《Oncology Progress》 2004-06
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<title>inical study of the Guben Xiaoliu Capasule effects in the treatment of advanced non-small cell lung cancer

<author>ng Xiaomin Yu Rencun Xin Hai, et al.Department of Oncology, Beijing Traditional Chinese Medicine Hospital, Beijing 100010  
abstractjective To observe the effect of Guben Xiao liu Capsule (GBXLC) in the treatment of advanced non small cell lung cancer (NSCLC). Methods 198 NSCLC patients were divided randomly into three groups. They are group A, GBXLC plus chemotherapy; group B, GBXLC alone, group C, chemotherapy alone. Results The response rate in three groups was16.7%, 3.1%, and 8.4% respectively. The response rate in group A was better than that in group C. After treatment, the symptoms, KPS, were all improved in group A and group B, better than that in group C. The median survival time in three groups was 15, 12 and 9 months respectively. The 1-year、2-year and 3-year survival rate in group A were 57.4%, 11.1% and 3.7%; in group B were 67.7% , 9.38% and 3.13% ; in group C were 39.6% , 4.17% , and 3-year survival rate is 0. The chemotherapeutic toxicities were mainly bone marrow depression, decrease of WBC, gastrointestinal disturbance and hair loss. But the toxicity occurring rate and toxic degree was much sh'ghter in group A thanthat in group C. Conclusion GBXLC can be used for NSCLC treating. It may stable the cancer lesion, relieve the symptoms, improve quality of life and prolong survival time. GBXLC may strengthen the efficacy of chemotherapy and relieve the side effects of chemotherapy.
【CateGory Index】: R734.2
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