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《Journal of Bengbu Medical College》 1990-01
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A QUANTITATIVE STUDY OF β-HCG IN TROPHOBLASTIC TUMORS

Zhang Suifu, Xie Qun, Yao Min, Wang Ping, Xiong Shigang, Liu Sengui (Department of Pathology, Bongbu Medical College, Anhui )  
Microspectroscopic measurement of the β-HCG content of trophoblastic cells were made in 52 choriocarcinomas, 49 invasive moles, 30 hydatidi-form moles, and 15 normal placental tissues. The principal findings were the following. (1) The mortality of patients with the syncytiotrophoblast-predominant type was lower than that of the cytotro-phoblast-predominant type. ( 2 ) The β-HCG content of trophoblasts of choriocarcinoma was higher than that of the invasive moles and normal placental tissues ( P0.001 ). ( 3 ) In invasive mole, the degenerative type had lower β-HCG content as compared with the proliferative type ( P0. 002 ) . ( 4 ) The β-HCG content of trophoblast in choriocarcinoma and invasive mole was positively correlated with the degree of trophoblastic proliferation. ( 5 ) Hydatidiform mole was similar to normal placental tissues in the β-HCG content ( P0.05 ). The chang of β-HCG content of trophoblasts reflected the number of surviving cells, their proliferative ability and the degree of proliferation of the trophoblast. This might serve as a useful parameter in predicting the effectness of treatment and the probable outcome of the disease.
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
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