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《Journal of Bengbu Medical College》 1990-01
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STUDIES ON THE β-HCG AND CLINICAL PATHOLOGY OF HYDATIDIFORM MOLE

Xie Qun, Zhang Shifu, Yao Min, Wang Ping, Xiong Shigang, Liu Sengui (Department of Pathology, Bengbu Medical College, Anhui )  
The relationship between the trophoblast-predominant type, β-HCG content, and malignant change rate in 74 cases of hydatidiform mole was studicd using immunohistochemistry and micro -spectroscopic image analysis methods. It was found that ( 1 ) malignant change rate in the syncytiotrophoblast-predominant type was lower that in the intermediate-cytotrophoblast predominant type; ( 2) in case syncytiotrophoblasts with a higher β-HCG content, the rate of malignant change of hydatidiform mole was decreased; (3) the relationship between the degree of tro-phoblastic proliferation and malignant change rate did not reach statistical significance. Our findings suggest that pathologic examination and β-HCG assay of trophoblast may be of help in predicting the prognosis of hydatidiform mole.
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【Co-references】
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