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《Journal of Bengbu Medical College》 2004-06
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Survey of Gram-negative bacili resistance in Intensive Care Unit

He Xian-di,Li Feng,Wu Qiang (Intensive Care Unit,Affiliated Hospital of Bengbu Medical College,Anhui 233004,China)  
Objective:To observe the Gram-negative bacterial resistance in patients in Intensive Care Unit(ICU) and to discuss how to treat infections caused by these resistant strains.Methods:The minimal inhibitory concentrations of 10 antibiotics against 160 strains of Gram-negative bacilli isolated from ICU patients were determined by E test.Results:The resistance rates to imipenem,cefepime and sulbactam-cefoperazone were the lowest,being 11.3% 、18.8% and 20.6%,respectively.Forty-one ESBLs-producing strains were susceptible to imipenem,cefepime and sulbactam-cefoperazone,with a susceptible rate of 90.2%,82.9% and 80.5%,respectively.Conclusions:Imipenem is the most active agent against severe systemic infections caused by ESBLs-producing strains,while β-lactam/β-lactamase inhibitors are also active against most strains.
【CateGory Index】: R181.3
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