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《Journal of Bengbu Medical College》 2006-01
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Effect of acute cold stress by immersing in water on the release of nitric oxide in cerebral cortex of rats

GAO Li~1,GUAN Su-dong~2,ZHU Yan~2(1.Department of Neurophysiology,Anhui Medical University,Hefei 230032;2.Department of Physiology,Bengbu Medical College,Bengbu 233030,China)  
Objective:To elucidate the changes of nitric oxide production in cerebral cortex of rats under acute cold stress by immersing in water.Methods:Twenty-seven male adult rats were randomly divided into three groups.Group A was a control group and rats in which were without any treatment.Rats of group B were put into cold water for 30 minutes and rats of group C were put into cold water for 60 minutes.The level of nitric oxide in cortex of rats were deteated by using NO deteat Kit.Results:The levels of nitric oxide in group A,B,and C were(4.36±1.79) mmol/g pr;(2.79±2.00) mmol/gpr,and(11.50±2.34) mmol/gpr,respectively.Conclusions:Nitric oxide may play a protective role in the early stage of acute cold stress.
【Key Words】: nitric oxide stress immerse in water cerebral cortex rats
【Fund】: 安徽省教育厅自然科学研究资助项目(2004kj272zd)
【CateGory Index】: R363
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