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《Journal of Bengbu Medical College》 2007-06
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Relationship between cerebrovascular disease complication and plasma high-sensitivity C-reactive protein level in patients with chronic renal failure

LIU Gui-ling1,2,ZHANG Bai-ke1,CHEN Wei-dong2(1.Department of Nephrology,The First Affiliated Hospital of Anhui Medical University,Hefei 230032;2.Department of Nephrology,The First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China)  
Objective:To study the relationship between cerebrovascular accident complication and plasma high-sensitivity C-reactive protein(Hs-CRP) level in patients with chronic renal failure.Methods:Twenty-eight cases of chronic renal failure with cerebrovascular accident complication(groupA) and 32 cases without cerebrovascular accident complication(group B)were detected of the levels of plasma Hs-CRP,age,plasma triglyceride(TG),total cholesterol(CHO),high-density lipoprotein cholesterol(HDL),serum creatinine(Scr),plasma albumin(ALB)and blood urea nitrogen(BUN).The results were compared with those of 30 healthy ontrols(group C).Results:The level of plasma Hs-CRP in group A and group B was significantly increased compaired with that of group C(P0.01).The level of plasma Hs-CPR in group A was significantly increased compared with that of group B and the difference was great(P0.01).The level of Hs-CRP was apparently affected by plasma triglycericle TG,CHO,HDL,Scr,ALB and BUN,but had no relations with age(P0.05).Conclusions:The Hs-CRP level is high in patients with chronic renal failure accompanied by cerebrovascular accident complication.Observation of Hs-CRP level is essential to predict the occurrence of cerebrovascular accident complicatio in patients with chronic renal failure.
【Fund】: 安徽省教育厅自然科学研究资助项目(2005kj290)
【CateGory Index】: R692.5
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