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《Acta Acadimae Qingdao Umvesitatis》 2003-04
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LI Tie shan, YAN Wen jing, LI Pei yuan\ (Department of Neurology, The Affiliated Hospital o f Qingdao University Medical College, Qingdao 266003, China)\;  
Objective\ Objective To explore the electrop hysiologic mechanism of patients with hemifacial spasm (HFS). Methods\ The latency, amplitude and the ratio of the amplitude of o rbicularis oris and orbicularis oculi of blink reflex were determined with EMG in 28 HFS patients and 11 normal controls. The ephaptic transmission of the two groups was observed.\ Results There was no significant difference of the amplitude and l atency of the orbicularis oculi of blink reflex between the two groups ( t=1.0 56-1.121, P 0.05); no significant difference between healthy and affected sid e ( t=0.855-0.967, P 0.05). Significant difference existed in the incidence of R1 or R2 between the two groups ( t=2.058, P 0.05), and in the ratio of the amplitude of orbicularis oris and orbicularis oculi ( t=2.236-2.495, P 0.05).No ephaptic transmission existed in the controls.\ Conclusion The recovery and denudation of synapses after injury of the facial nerve decrease inhibition of the cortex to the facial nerves. The ac tivity of facial nucleus increases, and leads to the abnormal spread of impulse, which is the main electrophysiologic mechanism of HFS.
【CateGory Index】: R745.12
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