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《Acta Acadimae Qingdao Umvesitatis》 2005-02
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EFFECT OF WEI-AOXIN ON CEREBRAL HEMODYNAMICS IN PATIENTS WITH HYPERTENSION AND CAROTID ARTERY ATHEROSCLEROSIS

LIU Song, SHENG Wen-xu, ZHANG Yong (Department of Cardiology, The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003, China)  
Objective To study the effect of Wei-aoxin on patients with hypertension and carotid artery atherosclerosis(CAA). Methods Fifty patients with hypertension and CAA were treated with Wei-aoxin 160mg t.i.d. for six weeks. Changes of hemodynamics in patients with cerebral ischemia were examined before and after the treatment. The results were compared with those of 30 normal controls. Results Average blood flow velocity increased significantly (t=1.85-8.16, P0.05) after the treatment with Wei-aoxin in patients with brain ischemia. Pulse index reduced significantly (t=1.67-7.09, P0.05). Conclusion Wei-aoxin is effective in increasing blood flow of cerebral arteries and can effectively treat and prevent insufficient cerebral blood supply.
【Key Words】: <Keyword> hypertension artherosclerosis Wei-aoxin hemodynamics ultrasonography Doppler transcranial
【CateGory Index】: R544.1
【DOI】: cnki:ISSN:1001-4047.0.2005-02-004
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1 Wang San Long1,2, Cai Bing1, Cui Cheng Bin1,3, Liu Hong Wei2, Wu Chun Fu2, Yao Xin Sheng2,4 1.Tianjin Institute for Biomedicinal Research(TIBiR),Tianjin,300384, P.R.China 2.The School of Traditional Chinese Materia Medicas,Shenyang Pharmaceutical University, Shenyang,Liaoning,110016, P.R.China 3.Ocean University of China, Qingdao,Shandong,266003, P.R.China 4.Traditional Chinese Medicines & Natural Products Research Center, Shenzhen,Guangdong,518057, P.R.China;Apoptosis of Human Chronic Myeloid Leukemia K562 Cell Induced by Prosapogenin B of Dioscin (P.B) In Vitro[J];Chinese Journal of Cancer;2003-08
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