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《Acta Academiae Medicinae Qingdao Universitatis》 2007-01
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CHANGES OF PLASMA VASCULAR ENDOTHELIAL GROWTH FACTOR AND VON WILLEBRAND FACTOR IN PATIENTS WITH DIABETIC RETINOPATHY AND THEIR CLINICAL SIGNIFICANCE

LIU YUN-LING,YANG ZHONG-SI,CONG YU-ZI,et al(Department of Diagnostics,Wendeng No.2 People Hospital,Wendeng 264400,China)  
ObjectiveTo explore the changes of plasma vascular endothelial growth factor(VEGF) and von Willebrand factor(VWF) in patients with diabetic retinopathy(DR) and their significance.MethodsBy using ELISA,the changes of plasma VEGF and VWF were detected in 58 DR patients,of whom,non-proliferative DR(NPDR),28 cases;proliferative DR(PDR),30.The results were compare with 54 non-diabetic retinopathy (NDR) patients,and 49 healthy ones served as controls.Results The plasma VEGF and VWF were higher in the diabetic than those in the controls(t=27.09,28.85;P0.001).The VEGF and VWF were higher in DR patients than those in NDR(t=10.35,16.02;P0.001).The VEGF and VWF were higher in patients with PDR than those in NPDR(t=6.74,7.01;P0.001).There were positive correlation between VEGF and VWF in NPDR and PDR(r=0.560,0.629;P0.001).ConclusionThe changes of VEGF and VWF involve in the occurrence and development of DR,which are responsible for the seriousness of DR.
【CateGory Index】: R774.1
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【References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Peng,TANG Rong-hua(The Clinical Laboratory of Yijishan Hospital,Wannan Medical College,Wuhu,241001,China);Clinical Significance of von Willebrand Factor and Antithrombin in Diabetes Mellitus with Retinopathy[J];Chinese Journal of Thrombosis and Hemostasis;2012-04
【Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHU Min-yan, H AN Li-rong. Department of Ophthalmology, Changhai Hospital, Second Military Med ical University, Shanghai 200433, China;Investigation of concentration of vascular endothelial growth factor in plasma and intraocular liquid in diabetic retinopathy[J];Chinese Journal of Ocular Fundus Diseases;2004-06
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 FAN Wei-jie,BAO Ning,TAO Li-ming.Nanjing First Hospital,Jiangsu Province 210006,China;Expression of vascular endothelial growth factor in experimental anterior segment ischemia in rabbits[J];Journal of Clinical Ophthalmology;2010-06
2 LIU Xiu-lan,GAO Li-li(Inner Mongolia Medical College,Hohhot 010059 China);VASCULAR ENDOTHELIAL GROWTH FACTOR AND DIABETIC RETINOPATHY[J];Acta Academiae Medicinae Neimongol;2006-S1
3 Li YF, Zhou P. Department of Ophthalmology, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China;Vascular endothelial growth factor and neovascularization in radiation retinopathy[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-06
4 ZHENG Tian-Sheng,ZHANG Xue-Dong From the Department of Ophthalmology,the First Hospital Affiliated to Chongqing Medical University,Chongqing 400016,China;Research advances of interventions on the expression of adhesion molecules and leucostasis in diabetic retinopathy[J];Recent Advances in Ophthalmology;2006-08
5 HOU Cheng-Hua,LIU Cheng-Yu From the Department of Ophthalmology,Wendeng Central Hospital of Weihai(HOU Cheng-Hua),Weihai 264400,Shandong Province,China;Diagnostics Department of Qingdao Medical College(LIU Cheng-Yu),Qingdao 266021,Shandong Province,China;Changes of plasma vascular endothelial growth factor and cell adhesion molecules in patients with diabetic retinopathy and its clinical significance[J];Research Advances in Ophthalmology;2007-01
6 Ningyan Bai, Shibo Tang, Jianxian Lin, Banghao Zhu, Yan Luo, Shaofen Lin Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China Department of Pharmacology, Zhongshan Medical College, Sun Yat-sen University, Guangzhou 510089, China;Study on Relationship between Leukocytes and Early Diabetic Retinopathy[J];Eye Science;2002-02
7 ZENG Ping2,LI Xiaoxia3,OU Yangfang4,et al.2 Shenzhen Eye Hospital,Shenzhen 518001,China;Experimental study on the influence of Tangwangyihao(糖网一号) decoction on the expression of intercellular adhesion molecular-1 in diabetes mellitus rat′s retina[J];Journal of Traditional Chinese Ophthalmology;2007-06
8 YU Ying,MIAO Wan-hong,YE Weicheng,et al. Shu Guang Hospital,Affiliated to Shanghai University of Traditional Chinese Medicine,China;Effect of Yiqi Yangyin Huoxue Formula used during perioperative period on the change of vascular endothelial growth factor (VEGF) in diabetic rabbits aqueous after phacoemulsification[J];China Journal of Chinese Ophthalmology;2010-03
9 HAN Jin-dong, YAN Hua. Department of Ophthalmology, General Hospital of Tianjin University of Medical Sciences, Tianjin 300052, China;Expression of vascular endothelial growth factor in aqueous humor and vitreous body of eyes with proliferative vitreo-retinal diseases[J];Chinese Journal of Ocular Fundus Diseases;2006-05
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Yan-Nian Hui, Lin WangInstitute of Ophthalmology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China;Introduction to the international clinical classification of diabetic retinopathy and diabetic macular edema[J];International Journal of Ophthalmology;2004-01
2 Shi-Jun Jiang1, Jin-Hong Cao2 1Department of Ophthalmology, the Second People's Hospital of Lianyungang, Lianyungang 222023, Jiangsu Province, China; 2Department of Ophthalmology, Huguosi Traditional Chinese Medical Hospital of Beijing University of China Medicine, Beijing 100035, China;The effects of ligustrazine lontophoresis for patients with diabetic retinopathy[J];International Journal of Ophthalmology;2006-04
3 Yan Wu, Hong-Bin L, Ling Jiang, Hong-Xia Liao Department of Ophthalmology, the Affilliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China;Advances of polyol pathway and diabetic retinopathy[J];International Journal of Ophthalmology;2009-02
4 YANG Yang,QI Yong-jun,LIANG Feng-ming.Zhuhai Branch,TCM Hospital of Guangdong Province,Zhuhai 519015,Guangdong,CHINA;Efficacy and factors affecting laser photocoagulation in the treatment of diabetic retinopathy[J];Hainan Medical Journal;2011-12
5 LIU Yu1,XU Xueliang2(1.Department of Ophthalmology,Third Xiangya Hospital,Central South University,Changsha 410013;2.Department of Ophthalmology,Xiangya Hospital,Central South University,Changsha 410008,China);Visual prognosis of laser treatment for diabetic retinopathy[J];Journal of Central South University(Medical Sciences);2009-03
6 CUI Dan1,WANG Zhe2,and YANG Xiang-Hong2(1.Department of Pathology,Liaoning Medical College,Jinzhou 121001,China;2.Department of Pathology,Affiliated Shengjing Hospital of China Medical University,Shenyang 110004,China);Effect of Advanced Glycation End Products on Inducing Rat Retinal Microvascular Endothelial Cells to Form New Blood Vessels[J];Chinese Journal of Arteriosclerosis;2009-09
7 JI Hui-qian,LI Lin-li,LIANG Min, LIU Xin-min.Department of Ophthalmology,Qingdao NO.8 People's Hospital,Shandong 266100;To discuss the operation opportune of vitrevtomy in diabetic retinopathy[J];Journal of Clinical Ophthalmology;2010-01
8 NI Qing (Guang′anmen Hospital,China Academy of TCM,Beijing 100053,China);Treating the Diseases in terms of Liver,Spleen and Kidney,Principle of Treatment is Nourishing Yin and Expelling Blood Stasis ——professor Lin Lan′s experience in treatment of diabetes retinopathy[J];Liaoning Journal of Traditional Chinese Medicine;2001-05
9 GAO Hong-jie1,YANG Ying-xia2(1.Institute of Traditional Chinese Medical Informatics,China Academy of Traditional Chinese Medical Sciences,Beijing 100700,China;2.Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing 100700,China);Chinese Medicine Treatment of Diabetic Retinopathy Research[J];Journal of Liaoning University of Traditional Chinese Medicine;2012-08
10 WANG Yan,LI Zhi - ying,YU Yang - gui The First Affiliated Hospital of Guangzhou University of TCM,Guangzhou 510405,China;Treatment of Diabetic Retinopathy by Herbal Medicine Associated with Ocular Direct - Current Ion - Introduction of Ligustrazine: A Clinical Observation of 74 Cases[J];New Journal of Traditional Chinese Medicine;2006-01
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 ZHENG Jun-li;TAO Guan-jun;PENG Lin;DING Zhong-yang;GU Zheng-hua;ZHANG Liang;SHI Gui-yang;School of Biotechnology,Jiangnan University;National Engineering Laboratory for Cereal Fermentation Technology,Jiangnan University;State Key Laboratory of Food Science and Technology,Jiangnan University;;Study on Submerged Fermentation of Tremella aurantialba Based on Inhibition of Non-Enzymatic Glycosylation[J];Journal of Food Science and Biotechnology;2013-08
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