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《Acta Academiae Medicinae Qingdao Universitatis》 2012-02
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THE VALUE OF APPARENT DIFFUSION COEFFICIENT IN ASSESSMENT OF CHARACTERS OF PERILESIONAL EDEMA IN DIFFERENT BRAIN DISEASES

NIU Lei,LIU Xuejun,SUI Qinglan (Department of Radiology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China)  
Objective To assess the value of apparent diffusion coefficient(ADC) in differentiation of the character of perilesional edema of different intracranial diseases. Methods Seventy-six patients with brain diseases(30 metastatic brain tumors,26 gliomas including 21 Ⅲ-Ⅳgrade glioma,and 20 brain abscess) underwent routine and diffusion-weighted MR imaging,meanwhile,some patients underwent enhanced MRI.The greatest length of perilesional edema in all the patients was ≥10 mm,which was then divided into two areas: proximal and distal edema,the ADC values were measured in the two areas,and that in corresponding normal alba were detected as well.The rADC values of proximal and distal edema areas were calculated. Results The value of rADC in proximal edema area in metastatic tumor was markedly higher than that in glioma and brain abscess,the differences between them were significant;in distal edema area,the differences of rADC values among them were not significant.In metastatic tumor,the rADC in proximal edema area was higher than that in distal area,the difference being significant(t=2.068,P0.05);in glioma,the values of rADC in both proximal and distal area were not significantly different compared with that of brain abscess(t=-1.068,1.302;P0.05).In glioma and brain abscess,their values of rADC in proximal area versus distal area were not statistically different(t=0.935,-0.433;P0.05). Conclusion The rADC have a certain value in determining the nature of perilesional edema caused by glioma,metastatic tumor and brain abscess.
【CateGory Index】: R445.2
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