CHROMOSOMAL HOMOLOGY BETWEEN HUMAN AND RHESUS MONKEY BY CHROMOSOMAL PAINTING WITH HUMAN WHOLE CHROMOSOME PROBES
HUANG Hao Jie ZHANG Xi Ran PAN Shu Juan CHEN Yi Feng (Department of Biology, Nanjing Normal University, Nanjing 210097,China) YU Long ZHAO Shou Yuan (Genetic Institute of Fudan University, Shanghai 200433, China) HUANG Gong Qing (Suzhou Z
Chromosomal painting was performed on both human and rhesus G banding chromosomes with 24 human chromosome specific DNA probes. Rhesus chromosome 9 and 15 were both painted by human chromosome 2. Three pairs of human chromosome probes (7 and 21, 14 and 15, 20 and 22) hybridized to single rhesus chromosome 2, 7, and 13 respectively, the rest rhesus chromosomes were heavily painted by their corresponding human chromosome specific DNA probe. Some chromosome rearrangements such as inversion and fusion (or fission) between human chromosomes and their homologues of rhesus monkey were uncovered by comparison of G banding patterns. Four kinds of mechanisms that might have played a role in the evolution of human and rhesus chromosomes were proposed in this study.