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《JOURNAL OF ZHEJIANG COLLEGE OF TCM》 2000-01
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Long-period Virulent Test of Curcumin

Wo Xingde,Hong Xingqiu,Gao Chengxian,et al Molecular Medical Institution,Zhejiang College of TCM,Hangzhou(310009)  
Under the prerequisite that curcumin had no acute virulent function,we made a long-period virulent test of curcumin,two groups of animals with high and low dosages were formed,and continuously given drugs for 80 days,then we observed them for 2 weeks.The observed items were 10 biochemical indexes of blood,8 hematological indexes,general dissection and pathology.It turned out that all the quotas of the group with high dosage of curcumin [50mg/(kg·d)]and the one with low dosage[100mg/(kg·d)]had no clear difference from that of control group,therefore it's concluded that curcumin was safe if taken 80 days continuously under the dosages above.
【Key Words】： curcumin SD rats long-period vurulent test
【Fund】： 国家中医药管理局科研基金!92 B0 49
【CateGory Index】： R285
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