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《Journal of Zhejiang College of Tcm》 2003-03
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Weierkang Granule Treat Chronic Atrophic Gastritis

Chen Zhiyun,Mo Yunsong,Xiang Baikang,et al Hospital Affiliated to Zhejiang College of TCM,Hangzhou(310006)  
Objective:Observe the effects of Weierkang granule on chronic atrophic gastritis patients and model rats.Methods:(1)Clinical research:Choose 31 cases of chronic atrophic gastritis accompanied by intestinal changes and dysplasia definitely diagnosed by gastroscope and pathologic examination,who take Weierkang granule;observe the improvement of clinical symptoms.Remake gastroscopic and pathologic examination within 2 weeks after treatment to 19 cases,and observe the pathologic improvement.(2)Experimental research:Make rats CAG model with alcohol,deoxysodium cholate and ammonia water,then randomly divide them into high dosage and low dosage groups of Weierkang,folic acid group and model group,make another normal group.Observe gastric mucosa inflammation and atrophy after 13 weeks of treatment.Results:(1)Weierkang has good therapy to chronic atrophic gastritis,the total effective rate of patients' clinical symptoms is 78.95%;68.42%to atrophy;78.95%to intestinal gland change;6 cases of dysplasia patients are all reversed.(2)There's no marked meaning to the differentiation of gastric mucosa inflammation among the high dosage and low dosage groups of Weierkang,folic acid group,model group and normal group(P0 05).The rats of model group have severer gastric mucosa than those of normal group,whose differentiation has obvious meaning(P0 01). The rats of the high dosage and low dosage groups of Weierkang and folic acid group have less sever atrophy than those of model group,whose differentiation has very obvious or marked meaning (P0.01,P0.05).Conclusion:The traditional Chinese drug Weierkang has good curative effect to chronic atrophic gastritis patients,it can also improve and reverse the rats'gastric atrophy of experimental atrophic gastritis.
【Fund】: 浙江省科技厅资助项目 :No:943017;; 浙江省中医管理局资助项目 :No:2000C26
【CateGory Index】: R259.7
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Chinese Journal Full-text Database 2 Hits
1 XIE Hui-chen (Department of Medicine,Hubei Institute for Nationalities,Enshi 445000,China);Gastritis Granule Treat the Rats with Chronic Atrophic Gastritis[J];Journal of Hubei Institute For Nationalities Medical Edition;2005-01
2 CHEN Zhi yun,YAN Mao xiang,XIANG Bai kang,HUANG Miao zhen,WANG Shi (Zhejiang Hospital of TCM,Hangzhou 310006);The effect of Weierkang on the growth factors in the rats with chronic atrophic gastritis[J];Study Journal of Traditional Chinese Medicine;2005-01
Chinese Journal Full-text Database 4 Hits
1 Chen Zhiyun; Yan Maoxiang; Xiang Baikang; et al(The Hospital Attached to Zhejiang College of TCM, Hangzhou 310006);Research of Prevention and Treatment of Wei Er Kang on Experimental Gastric Precancerous Lesion in Rats[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-02
2 Yan Maoxiang ; Chen Zhiyun ; Cao Junmin , et al(The Affiliated Hospital to Zhejiang College of TCM, Hangzhou 310006);The Influence of Wei Er Kang on Immunologic Function in Rats[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-03
3 Chen Zhiyun ; Yan Maoxiang; Cao Juumin;et alThe Hospital Attached to Zhejiang College of TCM, Hangzhou (310006);Regulatory Effect of Wei Fr Kang on Oncogene[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-04
4 SI Jianmin, WU Jiaguo, CAO Qian, et al. Gastroenterologic Laboratory, Clinical Institute, Zhejiang University School of Medicine, Hangzhou 310016, China;Establishment of chronic atrophic gastritis and study of the factors inducing atrophy in a rat model[J];Chinese Journal of Digestion;2001-02
Chinese Journal Full-text Database 10 Hits
1 Chen Zhiyun ; Cao Junmin ; Yan Maoxiang; et al(The Affiliated Hospital to Zhejiang College of TCM, Hangzhou (310006));The Protective Function of Wei Er Kang on Gastric Mucosa Harm in Rats[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-03
2 Chen Zhiyun ; Yan Maoxiang; Cao Juumin;et alThe Hospital Attached to Zhejiang College of TCM, Hangzhou (310006);Regulatory Effect of Wei Fr Kang on Oncogene[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-04
3 WANG Shujie, LIU Qiquan, QI Yuan, et al. Department of Traditional Chinese Medicine, Second Hospital Affiliated to Baotou Medical College, Neimenggu, Baotou 014030;Effect of Dongxuexiao Jieduhuoxue decoction on endothelin in blood serum of rat with chronic atrophie gastritis[J];Hebei Journal of Traditional Chinese Medicine;2010-02
4 REN Shou-zhong1,HE Shu-hua2,GUO Jian-sheng3,ZHANG Jun-qing1,LIU Ming-sheng1(1.College of Pharmacy,Hainan Medical University,Haikou 571101;2.Pharmacy Department,Affiliated Hospital to Hainan Medical University,Haikou 571101;3.College of Pharmacy,Hunan University of TCM,Changsha 410208,China);Correlation between epidermal growth factor,gastrin,somatostatin and inflammatory cytokines and chronic gastritis in rats[J];Journal of Hainan Medical University;2011-02
5 ZHANG Wen-xian,JIANG Shi-hong,LIU Wang-gen(Henan Traditional Chinese Medicine College,Zhengzhou Henan 45008,China);Status and Progress in the Study on Gastric Precancerous Lesions with TCM[J];Journal of Henan Medical College for Staff and Workers;2010-01
6 Zhang Yanwei1 Guo Xijun2 Zhao Jianwen1 Hebei Medical University,Shijiazhuang,Hebei,China 050017 Chinese Hospital of Hebei Medical University Shijiazhuang,Hebei,China 050011;Research Progress of Chinese Medicine in Stomach Cancer Lesion[J];China Journal of Chinese Medicine;2012-01
7 FENG Xiu-xue,LINGHU En-qiang Department of Gastroenterology,Chinese PLA General Hospital,Beijing 100853,China;Establishment of animal chronic atrophic gastritis model[J];Journal of Chinese PLA Postgraduate Medical School;2012-06
8 YAO Chun, LI Na (First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine, Nanning 530001, Guangxi, China);Progress of Experimential Study on Replication of Animal Model of Chronic Gastritis[J];Journal of Liaoning University of Traditional Chinese Medicine;2010-01
9 WANG Chang-song1,WANG Qi-guo2,YU Jie1,MIN Li1,WU Yin-pan1(1.Fujian University of Traditional Chinese Medicine,Fuzhou 350108,Fujian,China;2.The Affiliated Second People's Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou 350003,Fujian,China);Impact on Gastric Mucosa Histopathology of Atrophic Gastritis by Traditional Chinese Drug Prescription Based on Asthenia Syndrome Depression Syndrome Poison Syndrome Static Blood Syndrome[J];Journal of Liaoning University of Traditional Chinese Medicine;2011-02
10 SU Kelei1,WANG Xiaona2,ZHU Fangshi3(1.First Clinical College of Nanjing University of Chinese Medicine,Nanjing 210046,Jiangsu,China; 2.Department of Gastroenterology of Third People's Hospital of Zhengzhou,Zhengzhou 450000,Henan,China; 3.Jiangsu Academy of Traditional Chinese Medicine,Nanjing 210028,Jiangsu,China);Study on Protective Effect of Weiwei No.1 Granule on Gastric Mucosa in Acute Gastric Mucosal Lesion Model Rats[J];Liaoning Journal of Traditional Chinese Medicine;2013-02
China Proceedings of conference Full-text Database 1 Hits
1 HE Xiao Hui,CHEN Wen,CHEN Jian ZHang,et al The Jiang Xi Traditional Chinese Medicine Profession Training College,Fuzhou(344000);The Experiemntal Study of Shuang Pu Powder Treating Chronic Atrophic Gastritis model Rats[A];[C];2008
Chinese Journal Full-text Database 10 Hits
1 PENG Jun1,CAO Dian-qun2,LI Xiao-yue3(1.Department of Pathology,Anqing Affiliated Hospital of Anhui Medical University;2.Department of Pharmacology,Anqing Institute of Health Science;3.Anhui Key Laboratory of Anti-immflammatory and Immunopharmacology,Hefei 230032);Effect of extraction from rhizoma alpiniae officinarum by CO_2 SFE on ulcer index and gastric secretion and somatostatin about stress ulcer[J];Anhui Medical and Pharmaceutical Journal;2008-10
2 SONG Bo-gen LY Yi-qing ZHAO Gui-fen SHI Hong-jun ZHU Qing-yan (Lab. of Cancer Research,, Shanghai Railway Medical College, Shanghai 200070);THE TRAUMATIC DEGREE OF GASTRIC MUCOSA AND PATHOGENESIS OF GASTRIC CANCER[J];Chinese Journal of Cancer;1993-05
3 MA Jing1, FU Nai yang2, LI Yu mei3, PENG Wen lie1, XU An long1*1.Department of Biochemistry and Center for Biopharmaceutical Research, College of Life Science, Zhongshan University, Guangzhou 510275, P.R.China2.Institute for Drug Control of Guangdong;Glycyrrhiza uralensis Fisch Extract Selectively Induces Apoptosis in Several Human Cancer Cell Lines in Vitro[J];Chinese Journal of Cancer;2001-08
4 Yuan Shu-Lan, Wang Xiu-Jie, Wei Yu-Quan Key Laboratory of Biotherapy of Human Diseases,Ministry of Education,West China Hospital, Sichuan University, Chengdu,Sichuan,610041, P.R.China;Anticancer Effect of Tanshinone and Its Mechanisms[J];Chinese Journal of Cancer;2003-12
5 Yan Maoxiang ; Chen Zhiyun ; Cao Junmin , et al(The Affiliated Hospital to Zhejiang College of TCM, Hangzhou 310006);The Influence of Wei Er Kang on Immunologic Function in Rats[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-03
6 Yin Hongwei Hospital Affiliated to Jiangsu University,Zhenjiang(212001);Effect Price Ratio to Two Plans of Tri-combination Removing H.Pylori[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-05
7 LI You tian 1* , XU Dan 1, ZHAO Li 1,LI Hong lin 1, DONG Yu xiang 1, HONG Ying jie 1 ZHANG Er li 1, ZHANG Dian jun 1,XU Cai yun 2, GAO Wen yan 1, HUO Yu ping 1, LI Qiu bo 1,LI Xiao chun 1 (1. Department of Chinese Traditional Medicine,First Hospital, Jilin University, Changchun 130021,China;2. Department of Animal Laboratory, School of Basic Medical Sciences,Jilin University,Changchun 130021,China);Effects of Sanshen Ziwei Yin on G cells and D cells of gastric mucosa in rats with chronic atrophic gastritis[J];Journal of Jilin University of (Medicine Edition);2004-01
8 Yang Yun (Institute of Basic Theory, China Academy of TCM, Beijing);Rat's Model of Spleen-Deficiency Syndorme Caused by Toil and Hunger or Overeating[J];;1989-02
9 Liu Tao1 Ni Kezhong2 Zhang Xia3(1Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102;2Tianshan Hospital of Traditional Chinese Medicine,Changning District of ShangHai,ShangHai 200051;3Beijing University of Traditional Chinese Medicine,Beijing 100029);Experimental Study on Wei-kang Granules in Treating Chronic Atrophic Gastritris (CAG)[J];China Journal of Traditional Chinese Medicine and Pharmacy;2007-05
10 SHU Chang-xing(Medical College of Jiujiang University,Jiujiang 332000,China);Modern confusion of TCM often out in 'etiology'[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 WANG Chen-guang;YANG Zong-bao;ZUO Bin-rong;XIE Yu-feng;LIU Qiong;Medical College of Xiamen University;Jiangxi University of Traditional Chinese Medicine;Futian Hospital of TCM;;Expression of the proliferation signaling pathway on the gastric mucosa cells in rats with acute gastric mucosa injury treated by acupuncture[J];China Journal of Traditional Chinese Medicine and Pharmacy;2014-09
2 Sun Huili1,Lu Weimin2 Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China 210029 Jiangsu Province Hospital of Chinese Medicine,Nanjing,Jiangsu,China 210009;Treatment of Precancerous Lesions of Gastric Canner with Traditional Chinese Medicine[J];China Journal of Chinese Medicine;2010-02
3 ZHANG Yue,XIE Sheng. Department of Gastroenterology,Chinese Medical Hospital of Liuzhou City,Liuzhou 545001,China;Review on the research progress of non-drug treatment of traditional Chinese medicine in chronic atrophic gastritis[J];Global Traditional Chinese Medicine;2011-05
4 LIAO Yu-xiu The ruikang affiliated hospital, Guangxi traditional Chinese medicine university.(Nanning, 530011, China);The Study Recent Condition in Experiment and clinical of Chronic Gastritis Treated by the Traditional Chinese Medicine[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2009-13
5 YANG Jin-xiang, WEI Yue, PENG Ji-sheng, HUANG Da-wei, AN Jing (Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100029);Clinical review on precancerous lesions of gastric canaer treated with Chinese medicine[J];Journal of Beijing University of Traditional Chinese Medicine(Clinical Medicine);2013-01
6 XU Chun 1,ZHANG Yonghong 1,ZOU Xi 2(1.Nanjing University of Chinese Medicine,Nanjing 210046,Jiangsu,China;2.Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210046,Jiangsu,China);Review on Research Progress of Compound Chinese Medicine Preparations in Preventing and Treating Gastric Cancer[J];Journal of Liaoning University of Traditional Chinese Medicine;2013-06
7 YANG Ruichun LUN Xin;Effect of Warming Acupuncture for the Treatment of Atrophy Gastritis:An Observation of 45 Cases[J];Journal of New Chinese Medicine;2008-12
8 YE Wu FANG Sheng-quan Yueyang Hospital of Integrative Chinese & Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine;Research Progress on Treatment of Precancerous Lesion of Gastric Cancer by Chinese Medicine[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2012-06
9 Lei Li;Ma Chunjie;Yang Xiping;Department of Radiation Oncology,Baotou Tumor Hospital;College of Traditional Chineses medicine,Inner Mongolia Medical University;;The Effect of Weihe Granule II on the Expression Level of EGF and EGFR in CAG Rats[J];World Chinese Medicine;2014-01
10 Liu Wang-gen, Jiang Shi-hong Department of Histology and Embryology, Henan College of Traditional Chinese Medicine, Zhengzhou 450003, Henan Province, China;Effects of huangqi jianzhong decoction on the expression of epidermal growth factor,mRNA of inducible Nitric-oxide synthase and epidermal growth factor receptor in stomach mucosa of chronic atrophic gastritis rats with syndrome of spleen deficiency[J];Chinese Journal of Clinical Rehabilitation;2006-43
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LI Deng-hua TIAN Zhi-gang ZHANG JieZHANG Jian-hua CU Zheng-yan (Department of Immunology, Shandong Academy of Medical Sciences, Jinan 250001);THE USE OF MTT ASSAY FOR THE RAPID TESTING OF CYTOTOXICITY OF DRUGS AGAINST NON-SOLIDTUMOR CELLS[J];Chinese Journal of Cancer;1991-03
2 Chen Zhiyun; Yan Maoxiang; Xiang Baikang; et al(The Hospital Attached to Zhejiang College of TCM, Hangzhou 310006);Research of Prevention and Treatment of Wei Er Kang on Experimental Gastric Precancerous Lesion in Rats[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;1998-02
3 Qiu Jiaxin et al. (Affiliated Longhua Hospital of Shanghai College of TCM, Shanghai);Effect of Chinese Herbs for Invigorating the Spleen and Tonifying the Kidney on Initiation and Promotion of Multiple Step Theory of Tumor Formation[J];;1993-05
4 Wang Zhao;Ying Huijun(People's Hospital,Beijing Medical University,Beijing,1000044);Relationship between Expression of p21ras and DNA Ploidy in Gastric Carcinoma and Atypical Hyperplasia[J];THE PRACTICAL JOURNAL OF CANCER;1996-02
5 Fan Yingchang, et al Dept. of Pathology, Traditional Chinese Medicine College, Tianjin;Experimental Study of CAG Animal Model Rats (Deficiency of Spleen-Qi Type) on Pathologico-Morphological and Ultra- microstructure Changing of Gastric Mucosa[J];Tianjing Medical Journal;1994-02
6 Deng Dajun, Gu Liankun, Zhu Shaoxia, et al. Beijing Institute for Cancer Research and School of Oncology, Beijing Medical University, Beijing, 100034;Expression of oncogenes during chemical gastrocarcinogenesis in rats[J];Chinese Journal of Digestion;1996-S1
7 HU Pinjin, ZENG Zhirong, LIN Hanliang, et al. Department of Gastroenterology, the First Affiliated Hospital, Sun Yat Sen University of Medical Sciences, Guangzhou 510080, China;Effect of eradication of Helicobacter pylori on development and reversion of atrophic gastritis in animal study[J];CHINESE JOURNAL OF DIGESTION;2000-03
9 Gao Chongfeng Lu Youyong (School of Oncology,Beijing Medical University ,,Beijing Institute for Cancer Research ,Beijing 100034.);Correlation of multiple gene changes with malignant phenotype of human gastric carcinoma[J];National Medical Journal of China;1996-09
10 Deng Dajun,Chang Yunsheng,Li Jiyou ,et al.Beijing Institute for Cancer Re-search and School of Oncology,Beijing Medical University,Beijing 100034;Comparison total N-nitrosamides in fasting gastric juice from srbjects in high and low risk areas ror gastric cancer[J];CHINESE JOURNAL OF ONCOLOGY;1997-02
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