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《Journal of Zhejiang College of Tcm》 2004-01
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Effects of Different Components of Cordycep Sinensis Polysaccharide on Immune Function

Yu Lixia,Zhang Bingbing,Ruan Yeping,et al Zhejiang College of TCM,Hangzhou(310053)  
Objective:To investigate the effects of different components of Cordycep sinensis polysaccharides on immune function of mice.Methods:One hundred male NIH mices were randomly divided into five groups:negative control group;Components Ⅰ,Ⅱ,Ⅲ,Ⅳ of polysaccharides groups.Administration of Cordycep sinensis polysaccharides to NIH mice was lasted for five days at the dose of 35mg/kg by intraperitoneal and subcutaneous.Compare the parmacodynamics of immune activity of different components to get the weight of thymus and spleen of mices injected intraperitoneal and calculate the Viscera index.Results:Different components of Cordycep Sinensis Polysaccharide could enhance the phagocytic function of Monocyte macrophages and weight of thymus and spleen of mice that was immunaly inhibited by dexamethasone.The effects of Components Ⅱ of polysaccharides and Components Ⅲ of polysaccharides on enhancing the Viscera index were much more obviously.Conclusion:These results indicated that different components of Cordycep sinensis polysaccharides could enhance immune response,spleen index,thymus index,the phagocytic function of Monocyte macrophages.There was no obvious difference between them.
【CateGory Index】: R285
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