Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Zhejiang College of Tcm》 2005-01
Add to Favorite Get Latest Update

Proteomics Effect of Treating Atherosclerosis Rat by Yinchenwulin Powder

Wang Dongsheng, Chen Fangping ,Yuan Zhaokai, et al XiangYa Hospital, Central South University, Changsha (410008)  
Objective: Proteomics is currently in a phase of technological development and establishment, demonstrating the capacity for high throughput, is a major challenge. It is used in life science research, particulay in the mechanism of tumrogenesis. Yinchenwulin powder, which was extracted from Chinese herbs, is used to treat the patients with atherosclerosis. We investigated the molecular mechanism of Yinchenwulin Powder on the atherosclerotic rats in this paper. Methods: The AS model wistar rats made by feeding with high grease food and AS enplaques were observed in the aorta after one month of feeding. By two-dimension electrophoresis,the proteins were separated, and as well as protein profiles of aorta tissue. Compared with the protein profiles of aorta tissue treated, model proteins in different expression were identified by Image-Master ID Elite 4.01 .Result: There were 1077+68 protein dots in aorta tissue treated,and 1106+84 in aorta tissue. Compared the protein profiles of aorta tissue treated with model, 556 proteins were found as dys-regulated. Among them,196 proteins were observed up-regulated and 364 proteins were seen down-regulated in aorta tissue treated.Conclusion: Yinchenwulin Powder which could treat atherosclerotic rat may associated with those protein regulated by itself,and it will provide a new method of molecular mechanism of Yinchenwulin Powder.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 WANG Dong-sheng1, YUAN Zhao-kai2, HUANG Xian-ping2, LU Fang-guo2, CHEN Fang-ping1, HUANG Xi-lian1(1 Xiangya Hospital Affi liated to Central South University, Changsha 410008,China; 2Institute of Chinese Medical Diagnosis,Hunan University of Traditional Chinese Medicine,Changsha 410007,China);Study on pathological mechanism of phlegm and blood stasis syndrome and gene expression in atherosclerotic rat[J];China Journal of Traditional Chinese Medicine and Pharmacy;2009-05
【Citations】
Chinese Journal Full-text Database 2 Hits
1 WANG Dong-sheng, YUAN Zhao-kai, CHEN Fang-ping, et al De-partment of Hematology, Xiangya Hospital, Central South University, Changsha (410008);Relationship between Pathological Development of Phlegm-Stasis and Expression of Actin in Vascular Smooth Muscle Cell in Atherosclerosis Rat Model[J];Chinese Journal of Integrated Traditional and Western Medicine;2004-03
2 YU Rong;WANG Dong-sheng; ZHOU Heng;et al (Hunan College of Traditional Chinese Medicine, Changsha(410007));Clinical and Experimental Study on Effects of Yinchen Wuling Powder in Preventing and Treating Hyperlipoproteinemia[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1996-08
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHAO Ling, WEI Hai-feng, ZHANG Li, LI Ya-li, LI Lin (Xuanwu Hospital of Capital Medical University; Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China);Study on biological basis of phlegm and blood stasis syndromes in TCM[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-08
2 WANG Dong-sheng, CHEN Fang-ping,YUAN Zhao-kai et al. Xiangya Hospital, Central South University, Changsha 41008, China;The Effect of Yinchenwulin Powder on the c-myc mRNA Expression of VSMC in Atherosclerosis Rats[J];Journal of Chinese Physician;2005-05
3 Huan Liwu Qian Hailing Lan Qingqiang Liu Zhiying;Clinical Control Observation On Treating Senile Hyperlipenia With Tong Mai Yi Shou Oral Liguid[J];GUANGXI JOURNAL OF TRADITIONAL CHINESE MEDICINE;1997-06
4 Li Jusheng,Wang Dongsheng,Chen Fangping,et al(Department of Hematology,Xiang Ya Hospital,Central South University,Changsha 410008,China);Effect of Yinchen Wulin Powder on Apoptosis of Rat with Atherosclerosis[J];Journal of Hunan Traditional Chinese Medicine University of Hunan;2005-06
5 WANG Dong-sheng~1 YUAN Zhao-kai~2 CHEN Fang-ping~1 HUANG Xian-ping~1 GUO Zhi-hua~1 XIAO Chang-jiang~1 LIANG Qing-hua~1 (1 XiangYa Hospital,Zhongnan University,Hunan 410008) (2 Hunan College of Chinese Medicine,Hunan 410008);Influence of Yinchenwulin Powder on actin expression in rats with atherosclerosis[J];Journal of Beijing University of Traditional Chinese Medicine;2006-07
6 SONG Jun-sheng,DONG Wen-jun,LU Xiao-zuo,et al (Tianjin University of TCM,Tianjin 300193,China);Qualitative evaluation on clinical controlled study of literatures on Wuling powder and Its modified formula[J];Journal of Tianjin University of Traditional Chinese Medicine;2008-01
7 Wen-Liang Lv, Hua-Feng Li, Department of Traditional Chinese Med- icine, Hubei College of Traditional Chinese Medicine, Wuhan 430061, Hubei Province, China Qing-Hua Gao, Laboratory of Pathogen and Pathology, Hubei Col- lege of Traditional Chinese Medicine, Wuhan 430061, Hubei Province, China;Effect of Qingre Huashi recipe on liver low density lipoprotein-receptor mRNA in rats with epidemic febrile disease of dampness-heat syndrome[J];World Chinese Journal of Digestology;2005-20
8 LUO Zhi-hua, JIANG San-yuan, ZHONG Miao-wen, TANG Rong-de, ZHANG Jian-min. Xinhui Hospital of Traditional Chinese Medicine, Jiangmen 529100, Guangdong, China;Experimental study of combining simavastatin with Zhimaishu(脂脉舒) in hyperlipidemia treatment[J];Chinese Journal of Integrated Traditional and Western Medicine in Intentire Critical Care;2004-02
9 Yin Wenxue;The Effect of Yinchenwuling Powder(茵陈五苓散) on the Expression of PDGF-A mRNA in Atherosclerosis Rats[J];Journal of Emergency in Traditional Chinese Medicine;2006-12
10 WANG Dong-Sheng TANG Fa-Qing XIAO Chang-Jiang et al.(1.Xiangya Hospital of Centre-south Unversity,Changsha 41008;2.Hunan University of Chinese Medicine);Effect and Mechanism of Yinchen Wuling Powder on Atherosclerosis Rats[J];Journal of Traditional Chinese Medicine;2008-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 He Dacheng Xiao Xueyuan (Institute of Cell Biology, College of Life Sciences: Beijing Normal University, 100875, Beijing, China);DIFFERENTIAL PROTEOMICS AND ITS APPLICATIONS[J];Journal of Beijing Normal University(Natural Science);2002-04
2 Jin Guangliang (Beijing University of TCM);ABSTRACTS OF ORIGINAL ARTICLES Discuss on Syndrome Genomics and Syndrome Proteomics[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-06
3 Jiang Hongmei et al (Guiyang Medical College);Molecular Mechanism of Yisheng Injection against Anoxia-Reoxygenation Injury to Endothelial Cells by Two-Dimensional Gel Electrophoresis[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-09
4 WANG Dong-sheng, CHEN Fang-ping,YUAN Zhao-kai et al. Xiangya Hospital, Central South University, Changsha 41008, China;The Effect of Yinchenwulin Powder on the c-myc mRNA Expression of VSMC in Atherosclerosis Rats[J];Journal of Chinese Physician;2005-05
5 Liang AiwuThe Second Affiliated Hospital, Guangxi TCM University 530011;Clinical Observation on Treating Chronic Obstructive Disease of Lung at the Acute Exacerbating Period with adding Suzi Jiangqi Decoction and Wuling Powder[J];Guangxi Journal of Traditional Chinese Medicine;2003-02
6 LI Jia bang, LI Ying, XIONG Guo liang, LI Xue wen ZHANG Xiang, CHEN Chang hua, YIN Quan rong Institute of Combined Traditional Chinese and Western Medicine, Xiangya Hospital(Changsha 410008) [;A further research on physiopathological basis of “Liver Yang Forming Wind Syndrome”[J];Bulletin of Hunan Medical University;2000-04
7 Li Jusheng,Wang Dongsheng,Chen Fangping,et al(Department of Hematology,Xiang Ya Hospital,Central South University,Changsha 410008,China);Effect of Yinchen Wulin Powder on Apoptosis of Rat with Atherosclerosis[J];Journal of Hunan Traditional Chinese Medicine University of Hunan;2005-06
8 CUI Li-yan, ZHANG Jie, WANG Tian-cheng (Department of Laboratory Medicine, the Third Hospital of Peking University,Peking 100083,China);The functional proteome preliminary study of rat arterial smooth muscle cells promoted by homocysteine[J];Journal of Medical Postgraduates;2004-04
9 HE Hua,KONG Lingsheng,GENG Houfa,et al(Affiliated Hospital of Jining Medical College);Proteomics Analysis of Neurolymph of Acute Cerebral Infarction Patient[J];Journal of Jining Medical College;2006-01
10 WANG Dong-sheng~1 YUAN Zhao-kai~2 CHEN Fang-ping~1 HUANG Xian-ping~1 GUO Zhi-hua~1 XIAO Chang-jiang~1 LIANG Qing-hua~1 (1 XiangYa Hospital,Zhongnan University,Hunan 410008) (2 Hunan College of Chinese Medicine,Hunan 410008);Influence of Yinchenwulin Powder on actin expression in rats with atherosclerosis[J];Journal of Beijing University of Traditional Chinese Medicine;2006-07
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Yin-qing,WANG Ning-sheng,Liu Qi-de et al.Institute of Clinical Pharmacology,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Evaluation of Toxicity of WLS[J];Chinese Journal of Modern Drug Application;2008-12
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved