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《Journal of Zhejiang University of Traditional Chinese Medicine》 2006-03
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Experimental Research on Xingnaojing Injection to Oxide Injury of Cerebral Ischemia Reperfusion

Zhang Hongbo~1,Dai Jianfeng~2,Zhang Binhui(director) 1.Zhejiang University of TCM,Hangzhou(310053);2.Zhejiang Provincial Hospital of TCM,Hangzhou(310006)  
Objective Experiment the effective method to improve cell injury of cerebral ischemia.MethodMake Mongolirn-Gerbil acute full cerebral ischemia model with ligation of double main carotid arteries,observe the influence of intervening abdomen injection of western medicine Nimodipin and TCM Xingnaojing on MDA and SOD in cerebral tissue of Mongolirn-Gerbil in acute period of ischemia reperfusion.ResultIt finds that Nimodipin and Xingnaojing both can markedly increase SOD activity and decrease MDA content,there’s no obvious difference between them,while there’s difference among different dosages of Xingnaojing,the effect is rising with dosage increased.ConclusionAs a Chinese drug of anti-free radical injury,Xingnaojing has similiar effect with Nimodipin.
【CateGory Index】: R285
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