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《Journal of Zhejiang University of Traditional Chinese Medicine》 2008-01
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The Expression of α-MSH in Four Different Animals' Scarfskin and Its Meaning

Yang Liu,Lv Rongfeng Southern Medical University,Guangdong Guangzhou(510515),China  
[Objective] To observe the expression of α-MSH in four different animals'scargskin and to study its meaning for finding a novel evidence to research zoopery of pigment disease.[Methods]Scarfskins sheared from four different animal's skin were made into specimens,and then treated with α-MSH under the technique of immunohistochemical staining.[Results]There were negative expressions of α-MSH in both the hair follicle melanocytes of the Kunming white-mouse and the scarfskin of the FMN white-guinea pig;while there was positive expression in both the hair follicle melanocytes of the C57BL/6J black-mouse and the scarfskin of the HARTLY brown yellow-guinea pig.[Conclusion]The two white-skin animals are suit for research of zoopery of increased-pigment disease,while the other two are suit for research of zoopery of reduced-pigment disease;and α-MSH is one of the most important indicators in the research of zoopery with pigment disease.
【CateGory Index】: R758.4
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