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《Journal of Zhejiang University of Traditional Chinese Medicine》 2008-03
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Effect of Dachengqi Decoction on Blood Coagulation in Patients with Sepsis

Wu Jiannong,Zhu Meifei,Lei Shu,et al Affiliated Hospital,Zhejiang University of Chinese Medicine,Hangzhou(310006)  
[Objective]To investigate the effect of Dachengqi Decoction on blood coagulation in patients with sepsis.[Methods]44 septic patients with normal blood coagulation were randomly divided into two groups:treatment group and control group.Both groups were treated with routine integrationt reatment,and additionally,the treatment group was treated with Dachengqi Decoction nasaltube.Prothrombirtime(PT),thrombin time(TT),activated partial thromboplast in time(APTT),fibrinogen(Fg) and platelet count(PLT) were detected before and 1,3,7 days after treatment in the two groups.[Results]At 7 days after treatment in the treatment group,PT,TT and A-PTT all increased,while both Fg and PLT decreased compared to those of the control group(P0.05).[Conclusion]Dachengqi Decoction has a protection on blood coagulation in patients with sepsis.
【CateGory Index】: R278
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