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《Acta Scientiarum Naturalium Universitatis Pekinensis》 2009-05
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Biomechanical Study of Obstructive Sleep Apnea Syndrome

ZHAO Xueyan,HUANG Renhan,LOU Hangdi,RONG QiguoDepartment of Biomedical Engineering,College of Engineering,Peking University,Beijing 100871  
A 3D FE model of the human upper airway was established based on CT data,which included upper airway,partitive maxilla,mandible and hyoid.A set of dynamic loads,based on the pressure-time curves in the literature,were exerted on the upper airway.The simulation results reveal that velopharynx is the region that is most prone to collapse,when the obstruction of airflow happens.The lesser dangerous regions are oropharynx and hypopharynx.The upper airway with normal anatomic structure can collapse under abnormal loads.During the obstruction of airflow,the variations of the sagittal diameters are larger than those of the transverse diameters in velopharynx,oropharynx and hypopharynx.Abnormal anatomic structure is not the necessary factor of OSAS(obstructive sleep apnea syndrome) event.
【Fund】: 国家自然科学基金资助项目(30500571)
【CateGory Index】: R766
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