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Extraction of Antitumor Component from Fruiting Body of Ganoderma Lucidum

Zhao Dongxu Wang Libo Yang Xinlin Zhu Hesun (Center for Research on Materials Science, Beijing Institute of Technology, Beijing100081)  
Aim To investigate the factors affecting the extraction of antitumor component from Ganoderma lucidum . Methods After being soaked in ethanol, the antitumor component was extracted by the method of percolation. The orthogonal design with table L 9(3 4) was taken. The relative content of antitumor component in the extract was estimated by its harmfulness to HeLa cell. Results The extract inhibits the growth of HeLa cell in vitro. Among the 4 factors affecting the percolation, the operating temperature was the most significant one associated with the harmfulness and the solvent volume was the least. Conclusion There were some components of inhibiting the growth of Hela cell in the fruiting body of Ganoderma lucidum. The percolating conditions: the soaking time of 1 d, the percolating rate of 0 5 mL·min -1 , the solvent volume of 200 mL and the temperature at 60 ℃, can ensure obtaining the best result of extraction.
【Fund】: 国家科技部基金
【CateGory Index】: R284.2
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Chinese Journal Full-text Database 6 Hits
1 CHU Yang et al(Department of Biochemistry,Yantai University,Yantai,Shandong 264005);Selection of Medium for Ganoderma lucidum[J];Journal of Anhui Agricultural Sciences;2008-05
2 ZAN Li-Xia (School of Biological Science and Engineering,Shaanxi University of Technology,Hanzhong,Shaanxi 723001);Analysis of Nutrition Components in Fruiting Bodies of Cultivated Ganoderma lucidum in Qinba District[J];Journal of Anhui Agricultural Sciences;2008-20
3 HUANG Shu-ming~(1,4),YANG Xin-lin~1,HUANG Jian~1,WU Jian-hua~1, XU Jian-lan~3,ZHU He-sun~2 (1.School of Life Science and Technology, Beijing Institute of Technology, Beijing100081, China; 2.School of Material Science and Engineering, Beijing Institute of Technology, Beijing100081, China; 3.Sanlian Hi-Tech Limited Company, Wuxi, Jiangsu214023, China; 4.Bengbu Technological Academy, Bengbu, Anhui233030, China);HPLC Fingerprinting of Triterpenoids from Ganoderma Lucidum[J];Journal of Beijing Institute of Technology;2004-05
4 Chu Yang,Ni Xinjiang(Department of Biochemistry,Yantai University,Yantai 264005);Compariative Study of Four Ganoderma lucidum Srtains[J];Forest By-Product and Speciality in China;2008-06
5 NIU Jun-fang 1,WANG Hong-geng 1,FANG Zheng 1, LI Zheng-ping 1,YAN Guan-qiang 2 (1.College of science Key Laboratory of Bioinorganic Chemistry of Hebei, AgricultureUniversity of Hebei,Baoding 071001,China; 2.College of Humanities,Agriculture Unive;Study on the extraction methods and the distribution of germanium in germanium-enriched Ganoderma lucidum[J];Journal of Agricultural University of Hebei;2002-04
6 NIU Jun fang,FANG Zheng,WANG Hong geng,WANG Guo chao (Key Laboratary of Bioinorganic Chemistry of Hebei, Bioinorganic Chemistry Laboratory, Agricultural University of Hebei, Baoding 071001, China);The research advance on the effective constituents of Ganoderma spp.[J];Journal of Agricultural University of Hebei;2002-S1
Chinese Journal Full-text Database 10 Hits
1 GUO Xiangkun,WANG Xiaoling,GU Huan,GUO Yixin,ZOU Lizhuang(School of Chemical and Environmental Engineering,China University of Mining and Technology,Beijing 100083,China);Research on polymer-modified mortar based on MATLAB[J];Sichuan Building Science;2008-02
2 Wu Bao-feng Liu Lele Fang Zhihong Liu Xueyan (Department of biotechnology,Xinyang agricultural college,Xinyang,464000);Effects of Nutrition Factors on Mycelium Growth of 51427 in Ganoderma lucidum[J];Anhui Agricultural Science Bulletin;2008-06
3 HAN Jin (College of Life Science,Lanzhou University,Lanzhou,Gansu 730000);Study on Selection of Extracting and Determining Methods for Ephedrine under Experiment Condition[J];Journal of Anhui Agricultural Sciences;2009-09
4 Zhao Shuxiang Qi Guoying;Analysis of Sampling Investigation and Inspection Problems in Sports Science Researches[J];JOURNAL OF BEIJING UNIVERSITY OF PHYSICAL EDVCATION;1998-03
5 ZHUANG Chang-ling (Xiangfan college,Xiangfan Hubei,441003 China);The Ⅰ/Ⅱ Mistakes Analysis of Control Chart[J];Journal of Changchun Teachers College;2001-02
6 NIU Jun fang,FANG Zheng,WANG Hong geng,WANG Guo chao (Key Laboratary of Bioinorganic Chemistry of Hebei, Bioinorganic Chemistry Laboratory, Agricultural University of Hebei, Baoding 071001, China);The research advance on the effective constituents of Ganoderma spp.[J];Journal of Agricultural University of Hebei;2002-S1
7 YOU Yang\+1,\ HU Geng dong\+1, WANG Yu ting\+2 (1 Freshwater Fisheries Research center of Chinese Academy of Fishery Sciences Wuxi,21408, China; 2 Dept. of Aquaculture, Dalian Fisheries Univ., Dalian 116023, China);Studies on the criteria of water temperature of \%Protosalanx hyatocranius\%[J];JOURNAL OF DALIAN FISHERIES UNIVERSITY;1999-03
8 Wang Zhanquan et al;Study on Orthogonal Experimental in Genetic Programming[J];COMPUTER DEVELOPMENT & APPLICATIONS;1999-02
9 Zeng Fuli;Pu Tongliang and Liu Fuquan(Biological Departement,Lonzhou University,Lonzhou 730000);ESTIMATION OF RUBISCO ACTIVITIES WITH GAS CHROMATOGROPHY[J];ACTA BOTANICA BOREALI-OCCIDENTALIA SINICA;1995-05
10 JIANG Wei1,2, LEE Xin-qing1, JIANG Qian1,2, HUANG Dai-kuan1,2 and CHENG Hong-guang1,21. State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China2. Graduate School of Chinese Academy of Sciences, Beijing 100049, China;;Kjeldahl method and the elemental analyzer method in measurement of total nitrogen in sediments: Comparison and its significance[J];Geochimica;2006-03
China Proceedings of conference Full-text Database 1 Hits
1 Li Haini (Undergraduate of Laboratory Medicine,Grade2003,Youjiang Medical College for Nationalities,Baise,Guangxi 533000) Huang Suoyi (Department of Chemistry,Youjiang Medical College for Nationalities,Baise,Guangxi 533000);THE POLLUTION OF MERCURY AND ITS HARM TO THE AROUND ANIMALS AND PLANTS AND HUMAN BODIES[A];[C];2007
Chinese Journal Full-text Database 10 Hits
1 Wang Xuemei Gao Sulian (Department of Chemistry Anhui University Hefei 230039);Studies on Optimum Conditions of Extracting Rough Glycyrrhizic Acid from Glycyrrhiza[J];JOURNAL OF ANHUI UNIVERSITY(NATURAL SCIENCES);1999-01
2 BAO Lin-lin~1,TU Xin-ming~1,JIANG Hong~1,TONG Wei~1,CONG Zhe~1,WEI Qiang~1,ZHU Hua~1,ZHANG Yang-qing~1,GAO Hong~1,DENG Wei~1,HUANG Lan~1,LIU Ya-li~1,WANG Jian-wei~2,QIN Chuan~1(1.Institute of Laboratory Animal Science,CAMS and PUMC,Beijing 100021,China;2.National Institute for Viral Disease Control and Prevention,China CDC,Beijing 100052,China);Study on Isolation and Identification of SARS Coronavirus in Experimentally Infected Rhesus Monkeys[J];Chinese Journal of Virology;2005-01
3 LIU\ Fuquan (College of Life Sciences,Peking University,Beijing,100871) ZHANG\ Yanwen (Department of Biology,Nankai University,Tianjin,30071) XU\ Zhihong (Chinese Academy of Sciences,Shanghai Institute of Plant Physiology,Shanghai,200032);Cloning and Primarily Detecting the Function of the Promoter Region of NFL Gene in Tobacco[J];ACTA SCICENTIARUM NATURALUM UNIVERSITIS PEKINESIS;2000-02
4 Zhang Jun ying Cai Xiao xia Gu Xiao yu Liu Ling (College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China);Effect of microwave radiation on curing of epoxy resin[J];Journal of Beijing University of Chemical Technology;2004-04
5 Lu Hai; Wang Shasheng; Li Yi; Jiang Xiangning; Li Fenglan. Experimental Center of Forest Biology, College of Plant Sciences, Beijing For. Univ., 100083, P.R.China.;Cloning of xylem-specific-expression promoter of glycine-rich-protein (GRP 1.8) gene from Ginkgo biloba.[J];Journal of Beijing Forestry University;2001-04
6 School of Pharmaceutical Sciences He Yunqing, Li Rongzhi, et al;STUDIES OF ACTIVE POLYSACCHARIDES OF GANODERMA LUCIDUM[J];;1989-03
7 WU Zhen bin,CHEN Hui rong,LEI La mei,SONG Li rong, FU Gui ping,JIN Jian ming,HE Feng,HE Zheng rong(State Key Laboratory of Freshwater Ecology and Biotechnology,Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan 430072,China);STUDY OF THE EFFECT OF CONSTRUCTED WETLAND ON THE REMOVAL OF MICROCYSTINS[J];RESOURCES AND ENUIRONMENT IN THE YANGTZA BASIN;2000-02
8 ZHANG Wei-hao~1, SONG Li-rong~2, XU Xiao-qing~2, LIU Yong-ding~2, ZHANG Xi-hui~1(1. Research Center for Environmental Engineering & Management, Shenzhen Graduate School of Tsinghua University, Shenzhen, 518057, China; 2. Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan 430072, China);PRIMARY RESEARCH OF THE MICROCYSTIN'S FATE IN NATURAL AQUATIC SYSTEM[J];Resources and Environment in the Yangtze Basin;2004-01
9 NIU Jun fang,FANG Zheng,WANG Hong geng,WANG Guo chao (Key Laboratary of Bioinorganic Chemistry of Hebei, Bioinorganic Chemistry Laboratory, Agricultural University of Hebei, Baoding 071001, China);The research advance on the effective constituents of Ganoderma spp.[J];Journal of Agricultural University of Hebei;2002-S1
10 ZHANG Zhao-qing; ZHANG Chi; WU Hao-jie (Henan Academy of Sciences, Zhengzhou 450008, China);Advances in the Mechanism Research about the Biological Effects of Microwave Electromagnetic Fields[J];JOURNAL OF MAGNETIC MATERIALS AND DEUICES;2000-01
China Proceedings of conference Full-text Database 2 Hits
1 Chu Zhide Zhang Fang Jiao Shilong Ma Yitai (School of Mechanical Engineering, Tianjin University, Tianjin, 300072);The Cure Mechanism of Nano-meter Medicine and Experimental Investigation of Microwave Extraction[A];[C];2005
2 LIU Yuanfa, HE Gaohong, LI Baoju (School of Chemical Engineering, Dalian University of Technology, Dalian 116012);Research developments of flux enhancement in membrane processes[A];[C];2006
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 WANG Xian-sheng et al (Department of Chemistry,Shangluo University,Shangluo,Shaanxi 726000);Discussion on Determination Method of Micro Magnesium in Spore Powder of Ganoderma lucidum[J];Journal of Anhui Agricultural Sciences;2007-19
2 YANG Jie,CUI Zheng-wei(School of Mechanical Engineering,Jiangnan University,Wuxi Jiangsu 214122,China);Development and Application of Microwave Pretreatment on Plants for Enhancing Efficacious Compounds Extraction[J];Packaging and Food Machinery;2009-03
3 YING Zhi, LI Jian-rong, HAN Xiao-xiang (College of Food Science and Bioengineering, Zhejiang Gongshang University, Food Safety Key Lab of Zhejiang Province, Hangzhou 310035, China);Research Progress of Polysaccharides in Morus alba L. Leaves[J];Modern Food Science and Technology;2007-11
4 GAN Zhi-yong(Quality Supervision and Testing Center of Subtropical Fruit and Vegetable, Ministry of Agriculture, Nanning 530001, China);Detetmination on organic germanium in flowers of yellow flower camellia by ICP-AES[J];Guangxi Agricultural Sciences;2009-07
5 XIAO Zi-tian1,YAN Yi3,HE Huan-qing1,TAN Zhi-yong3,GUO Ju-xian1,LI Shu-wen2,YE Yao-cheng4(1.Vegetable Research Institute,Guangdong Academy of Agriculture,Guangzhou 510640,China;2.Chengdu Lüheng Scienceand Technology Development Co.Ltd.,Chengdu 610036,China;3.Seed Research Center,Dongguan 511700,China;4.Heyuan Tianxianhu Agriculture Development Co.Ltd,Heyuan 517000,China);Compariative study of twenty-eight Ganoderma lucidum strains[J];Guangdong Agricultural Sciences;2009-09
6 HOU Rui-hong,LIAO Sen-tai(1.College of Food Science,South China Agricultural University,Guangzhou 510642,China;2.Sericulture and Agro-Processing Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510610,China);Research development of the artificial cultivation of Ganoderma Lucidum in China[J];Guangdong Agricultural Sciences;2009-11
7 GONG Jian-guo(Department of Biochemistry of Jining,Inner Mongolia Normal University,Wulanchabu,Neimenggu 012000);The use of Universal Design Optimization Rotation of the Medium of Ganoderma lucidum Research Home[J];Northern Horticulture;2010-04
8 ZHOU Ming1,2,DU Xin2,3,YANG De2,CHEN Wei1,2,XIONG Guang-quan1,2,YE Li-xiu1,2,HE Jian-jun1,2,GAO Hong2,SHI De-fang2,GU Feng2(1.Agricultural Products Processing Subcenter of Hubei Agricultural Science and Technology Innovation Center,Wuhan 430064,China;2.Institute of Agricultural Products Processing and Neutron-Agro Technology,Hubei Academy of Agricultural Science,Wuhan 430064,China;3.College of Food Science and Technology,Huazhong Agricultural University,Wuhan 430070,China);Effect of Ultrasound-microwave Treatment on Extracting Rate of Ganoderma lucidum Polysaccharides[J];Hubei Agricultural Sciences;2009-07
9 SHENG Dong-ming, MA Ying Northeast Agriculture University, Harbin 150030, China;Research Overview of Ganoderma Lucidum Polysaccharide[J];Journal of Cereals & Oils;2004-07
10 DU Xin1,2,ZHOU Ming1,CHEN Wei1,XIONG Guang-quan1,GAO Hong1,YANG De1,YE Li-xiu1(1.Institute of Agricultural Products Processing and Neutron-Agro Technology,Hubei Academy of Agricultural Sciences,Wuhan 430064,China;2.College of Food Science and Technology,Huazhong Agricultural University,Wuhan 430070,China);Radio-frequency Technology Extraction of Ganoderma lucidum Polysaccharides[J];Hubei Agricultural Sciences;2009-10
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Guan Hong-chang, Cong Zheng Department of Pharmacology, Beijing Medical College;EFFECTS OF LINGZHI POLYSACCHARIDE D_6 ON THE BIOSYNTHESIS OF NUCLEIC ACIDS AND PROTEIN[J];;1981-04
3 Gu Ligang Tao Gundi Zhao Zhongsheng Zhang Li Yan Xuanzuo Zhou Yong Dept. of Immvnology, Institute of Qigong Research Beijing College of Traditional Chinese Medicine, Beijing;IN VITRO AND IN VIVO STUDY OF THE EFFECT OF GANODERMA CAPENS TENG ON MOUSE IMMUNE RESPONSE[J];;1989-03
4 Chen Qi, Wang Minkai and Xu Linying (Jiangxi College of Traditional Chinese Medicine, Nanchang) (730 Pharmaceutical Factory, Jiangxi Communist Labour University);EXPERIMENTAL STUDY ON THE EFFECT OF LING-CHIH (GANODERMA) ON CORONARY CIRCULATION[J];Acta Pharmaceutica Sinica;1979-03
5 Liu Gengtao, Bao Tiantong, Wei Huailing and Song Zhenyu (Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing);SOME PHARMACOLOGICAL ACTIONS OF GANODERMA LUCIDUM AND G. JAPONICUM (FR) LLYOD ON MOUSE LIVER[J];Acta Pharmaceutica Sinica;1979-05
6 Gao Bin, Yang Gui zhen. Department of Immunology, Norman Bethune University of Medical Sciences, Changchun130021.;Effect of Gdnoderma applanotum polysaccaride on immune function of normal mouse and its tumor inhibiting action.[J];Chinese Journal of Immunology;1989-06
7 Xu Jin, Zhong Qiping and Lu Ding(Institute of Antibiotics, Beijing);Effect of Ganoderma Extract on Murine Immunocytes[J];Acta Academiae Medicinae Sinicae;1985-04
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