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《Beijing Biomedical Engineering》 2008-01
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High safety hybrid cryosurgical/hyperthermia probe via an adiabatic thin layer material

YAN Jingfu,LIU Jing,ZHOU Yixin,DENG Zhongshan Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing 100080  
Cryosurgical/hyperthermia probe system(CHPS)is a new generation medical equipment capable of treating tumors through a combination between localized fast freezing and heating.This system performs its role by inserting the probe into the deep target tissues under the guidance of certain routine medical imaging systems.During the cycles of freezing and heating,it is very important to protect the normal tissues and important organs along the inserting track of the probe from injury.Taking account of the special requirements of CHPS,a method is proposed in this paper to avoid such adverse situation through attaching an adiabatic thin layer material along the wall of the non-working region of the probe.Preliminary experiments were performed to evaluate the present method.Meanwhile,mathematical model is developed to characterize the bioheat transfer of living tissues after frozen by the probe and corresponding analytical solution for the steady state temperature profile was obtained.Parametric studies were provided as a theoretical basis for the future optimization design of probe.Both theoretical analysis and experimental results demonstrate the feasibility of using adiabatic biocompatible thin layer as a simple,flexible and effective way to prevent cold or heat release from the probe.This provides a valuable strategy to perform a safe and efficient freezing and heating treatment on tumor in the near future.
【Fund】: 国家自然科学基金(50436030)资助
【CateGory Index】: R318.52
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【Citations】
Chinese Journal Full-text Database 5 Hits
1 ZHANG Yan ting, LIU Jing.Cryogenics Laboratory,Technical Institute of Physics & Chemistry, Chinese Academy of Sciences, Beijing 100080, China;Study on Thermal Stress in Living Tissues during Cryosurgical Re-warming[J];Space Medicine & Medical Engineering;2002-04
2 Gu Boqin College of Mechanical Engineering, Nanjing University of Chemical Technology, Nanjing, 210009, China;INVESTIGATION OF LEAK DETECTION METHOD BY MEANS OF MASS SPECTROMETER[J];JOURNAL OF NANJING UNIVERSITY OF CHEMICAL TECHNOLOGY;2000-01
3 Yan JF, Zhou YX, Deng ZS, Xiang SH, Liu J Institute of Physics and Chemistry, Chinese Academy of Science, Beijing 100080, China;Performance of self-made cryosurgical and hyperthermia equipment for targeted tumor treatment[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-22
4 HUANG Jing-xiang~1,KONG Qing-hao~2,ZHANG Zhong-min~3(1.College of Mechatronics Engineering,China Jiliang University,Hangzhou 310018,China;2.Zhejiang Inspection Centerof Medical Instruments,Hangzhou 310009,China;3.Zhejiang Institute of Medical Instruments,Hangzhou 310009,China);Research on the development of cryosurery and high-vacuum insulating probing rods used in micro-injury operations[J];Journal of China Jiliang University;2006-03
5 ;The Study on Cryosurgery Tool Used for Body' s Organs[J];Journal of Rfrigeration;1990-01
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Li Yong Li Weiguang Zeng Zhixin(Advanced manufacturing Technology Lab,Mechatronic Engineering Dept.,SCUT,GuangZhou 510640);THE APPLICATION OF LIQUID N_2 REFRIGERATION IN MEDICINE[J];Gryogenics;2001-01
2 Huang Yaoxiong(Institute of Biomedical Engineering, Ji Nan University, Guang Zhou 510632);USE OF COLD TECHNOLOGY IN MEDICINE[J];Gryogenics;2004-03
3 Han Hongxin; Cai Jidao Yao Kemin (Shanghai Institute of Mechanical Engineering ref-Cryo Teach-Research Group);ANALYSIS OF TEMPERATURE FIELD IN A GOLDBOARD OF CRYOPUMP[J];Cryogenics and Superconductivity;1986-03
4 Zhang Zhongmin (Zhejiang Institute of Medical Instrument);ANALYSIS AND CALCULATION OF THE HEAT TRANSFER OF VAPORIZER IN CRYOSURGERY INSTRUMENT[J];Cryogenics and Superconductivity;1987-01
5 Shi Ying, Zhang Zhongmin, Yu Hua (Zhejiang Institute of Medical Instruments, Hangzhou 310009, China) Huang Jingxiang (China Institute of Metrogy, Hangzhou 310018, China);The Development of the Cryopreservation System of Biological Materials[J];Cryogenics and Superconductivity;2005-03
6 Zhang Zhongmin,Mao Xinxin(Zhejiang Institute of Medical Instruments,Hangzhou,310009);The Cryosurgical Instrument Used for Atrical Fibrillation[J];CRYOGENICS AND SUPER CONDUCTIVITY;1998-02
7 Gu Boqin College of Mechanical Engineering, Nanjing University of Chemical Technology, Nanjing, 210009, China;INVESTIGATION OF LEAK DETECTION METHOD BY MEANS OF MASS SPECTROMETER[J];JOURNAL OF NANJING UNIVERSITY OF CHEMICAL TECHNOLOGY;2000-01
8 ZHANG Ji-ren(Zhujiang Hospital, Sourthern Medical University, Guangzhou 510282, China);Endocare Targeted Cryoablation Therapy[J];Journal of Biomedical Engineering Research;2005-02
9 HUANG Jing-xiang~1,ZHANG Zhong-min~2(1.College of Mechatronics Engineering,China Jiliang University,Hangzhou 310018,China;2.Zhejiang Institute of Medical Instruments,Hangzhou 310009, China);Study on phase change freezing interface of biological tissues under low temperature conditions[J];Journal of China Jiliang University;2006-01
10 ;The Study on Cryosurgery Tool Used for Body' s Organs[J];Journal of Rfrigeration;1990-01
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