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A Research on Preventing Disuse Osteoporosis in the Indicator of Bone Metabolism Biochemistry through Passive Movement and Electricity Stimulation

LI Jun-han1,HUANG Lei2(1.P.E.College,Mianyang Normal University,Mianyang 621000,Sichuan China;2.Sichuan Orthopaedics Hospital,Chengdu 610041,Sichuan China)  
Objective: Through the experimental research,this paper discusses the preventive function of passive movement and electricity stimulation on rats with disuse osteoporosis.Methods: through cutting the sciatic nerve and femoral nerve of experimental rats,we make an animal model of disuse osteoporosis,and divide them into five groups,those are the fake operation group,the nerve cutting group(NCG),nerve cutting with passive movement groups(PMG),nerve cutting with electricity stimulation group(ESG),and nerve cutting with passive movement and electricity stimulation(PMESG).Then the changes of biochemistry indicators of bone metabolism in all groups are observed.Results: compared with Sham group,the BGP value of the other groups is markedly lower than it(P0.01),the sTRACP value of the other groups all have a significant rising,but is meaningless in statistics(P0.05).Compared with DNG,on one hand,the BGP value of the other groups is obviously rising,especially the BGP of the PMG+ESG is more higher than it(P0.05),on the other hand,the sTRACP value of the other groups all exhibite a very significant reduction(P0.01);Conclusion: cutting nerve of rats can make bone formation decrease and make bone absorption increase,but passive movement and electricity stimulation can inhibit the decrease of bone formation and the increase of bone absorption.It shows that passive movement and electricity stimulation can prevent the disuse osteoporosis made by cutting nerve on a certain extent.
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