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《Beijing Medical Journal》 2003-03
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The single-trial of visual evoked potential and the preliminary study on feasibility in clinical practice

Chen Kui,Pan Yingfu,Tie Yanmei,et al (Department of Neurology, Beijing Friendship Hospital,Beijing 100050)  
Objective To explore single trial of PRVEP and its feasibility in clinical practice.Methods By using the Galileo EP System,we tested both routine VEP and single trial (the first 5 single trial PRVEP epochs,sub average) with a new method which are combined optimal filtering,wavelet analysis and independent component analysis in 36 patients with the optic neuropathy and in 46 healthy subjects as control.Finally the result of all parameters were processed by the new method comparing with the results of custom method as gold standard.The sensitivity,specificity and accuracy were calculated.Results Taking P100 PL as criteria,the sensitivity of the new method was 95.6%(43/45),the specificity 95.0%(113/119),exact 95.1%(156/164).Conclusions The results obtained by the new method were similar to that of the custom method.Further more,the new method may be more sensitive than the custom one in detecting some sub clinical patients.It takes less time and can enhance the reliability of PRVEP.So the new method could be applied to clinical practice.
【Fund】: 北京市科委科研基金资助项目 ( 1992 ;;1994)
【CateGory Index】: R741
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