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《Beijing Medical Journal》 2007-09
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The relationship between homocysteine and carotid artherosclerosis in cerebral infarction patients

SHEN Yuan,YU Hua-feng,LU Buo-hua,et al(Department of Neurology,Beijing Tongren Hospital,Beijing,100730)  
Objective To investigate the relationship between homocysteine(Hcy) level and carotid artherosclerosis in cerebral infarction patients. Methods In 90 cerebral infarction patients and 40 healthy controls,serum homocysteine level was measured by cyclophorase assay,carotid artherosclerosis was determined by the use of the duplex ultrasonography. Logistic regression was performed to analyze the relationship between homocysteine,carotid artherosclerosis and cerebral infarction. Results The fast homocysteine level in the patient group was 22.32(17.05~27.18)μmol/L,significantly higher than that in the control group 12.71(9.63~16.48)μmol/L (P﹤0.001);carotid artherosclerosis was related to cerebral infarction; homocysteine level was related to the carotid artherosclerosis and cerebral infarction even after controlling for other traditional risk factors. Conclusions Serum homocysteine is the independent risk factor for cerebral infarction,and artherosclerosis is the probable linkage.
【CateGory Index】: R743.33
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