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《Beijing Medical Journal》 2010-04
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Platelet function analysis in regular blood donors

CHEN Min-cai, FENG Xue-Sheng, SONG Li-jie, et al (Department of Transfusion, 307 Hospital of PLA ,Beijing 100071)  
Objective To compare platelet function between regular multi platelet donation donors (2 times/month) and regular normal donors (1 time/month), and assess specific parameters to make a rational analysis of the donation interval to ensure the quality of platelets used for clinical purposes. Methods RBC, HGB, MCV, MCHC, RDW-SD, PLT, MPV, PDW and platelet aggregation rate were used to compare donations from regular multi platelet donors and regular normal donors. Results The indices of RBC, WBC, HGH, MCV, average red cells and RDW-SD showed no significant differences between the two regular donor groups. Significant differences between the two donor groups were detected in PLT, MPV, PDW indices and the platelet aggregation assay. Conclusions Despite the relatively high platelet counts among regular multi platelet donations donors, their platelet’s ability to aggregate in vitro decrease compared with that of regular normal donors. It is recommended to collect platelet from regular normal donors to ensure the quality of the blood platelet donations
【CateGory Index】: R446.1
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