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《Beijing Medical Journal》 2010-05
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The analysis of correlated factors of postoperative intracranial hemorrhage in epidermoid cyst

CHU Chun,LIN Song,ZHANG Mao-zhi,et al(Department of Neurosurgery,Beijing Tiantan Hospital,Beijing 100050)  
Objective To discuss the characteristics and correlated factors of postoperative intracranial hemorrhage of epidermoid cyst.Methods Clinical data of 428 patients with epidermoid cyst underwent craniotomy from 2002 to 2008 were analyzed retrospectively.Single-factor analysis and Logistic multivariate regression analysis were used to explore the correlated factors of postoperative intracranial hemorrhage of epidermoid cyst,and susceptible factors were screened.Results Postoperative intracranial hemorrhages occurred in 43 patients of the 428 patients(the incidence was 10.05%),among which the delayed hemorrhages(≥5 days postoperatively) accouned for 69.77% of the overall intracranial hemorrhages.The results of single-factor analysis showed that there was significant difference in tumor location(P=0.002),cerebral contusion(P=0.008) and postoperative meningitis(P=0.018) between bleeding group and non-bleeding group,and there was no significant differences in the remaining factors(age,sex,tumor size,capsule,texture,degree of adhesion,extent of resection and the application of intraoperative corticosteroids flushing).The results of Logistic multivariate regression analysis showed that the correlated factors were brain contusion(P=0.004,OR=7.07) and postoperative meningitis(P=0.016,OR=2.27).Conclusions The incidence of postoperative intracranial hemorrhage in epidermoid cyst is higher than other craniotomy,and most of the hemorrhages occur at about one week postoperatively.Location of tumor,brain contusion and postoperative meningitis are related to postoperative intracranial hemorrhage,particularly the latter two.
【CateGory Index】: R739.4
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