Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Beijing Medical Journal》 2010-07
Add to Favorite Get Latest Update

Efficacy of Omeprazole on digestive tract hemorrhage in critical diseased children

LIU Ming-yue, ZHANG Qi, WANG Fei, et al (Department of Emergency, Children’s Hospital Affiated to Capital Institute of Pediatric, Beijing 100020)  
Objective To evaluate efficacy of Omeprazole for the treatment of digestive tract hemorrhage in critical diseased children. Methods Forty-two critical diseased children with digestive tract hemorrhage in ICU were randomly divided into two groups. The treatment group was treated with Omeprazole [0.7mg/(kg·d)] and the control group was treated with Cimetidine. The effective rate, the stop time of hemorrhage and the duration of stay were compared. Results Between the treatment group and control group, the effective rate was 95.24% and 66.67% respectively(P 0.01). The hemorrhage stop day was 2.6 days and 4 days. The hospital days was 11 days and 14 days. Mild adverse side reactions were present in 1 patient and disappeared after Omeprazole discontinuation. Conclusions Our data suggests that Omeprazole treatment is effective but without severe adverse reactions. Omeprazole treatment can shorten the hemorrhage time and hos- pital days.
【CateGory Index】: R720.597
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 4 Hits
1 HUANG Jin-lin, LIU Nan, LI Hai-ling, et al (No. 401 Hospital of PLA, Qingdao 266071, China);Prevention and treatment of stress ulcer in critical case[J];Journal of Navy Medicine;2004-02
2 ZHAN Xianbao, LI Zhaoshen, CUI Zhong min, DUAN Yimin, NIE Shinan, LIU Jing, XU Guoming. Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai 200433,China;Changes of rat gastric mucosal barrier under stress conditions[J];Chinese Journal of Internal Medicine;2002-06
3 JIANG Qian,HUANG Xiao-jun,CHEN Huan, XU Lan-ping, LIU Dai-hong, CHEN Yu-hong, ZHANG Yao-chen, LIU Kai-yan, GUO Nai-lan,LU Dao-pei. Institute of Hematology, Peking University, People’s Hospital, Beijing 100044, China Corresponding author: HUANG Xiao-jun;Severe gastrointestinal bleeding after allogeneic hematopoietic stem cell transplantation——15 case analysis[J];Chinese Journal of Hematology;2005-05
4 ZHANG Tai-chang, WEI Jia-ping, DING Xiu-juan, et al. Xuan Wu Hospital, Capital University of Medical Sciences, Beijing 100053,China;Clinical characteristics of gastrointestinal hemorrhage in SARS and factors affecting its occurrence[J];Chinese Journal of Digestive Endoscopy;2003-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Zhang Xin Department of Pediatrics, the First People's Hospital of Huainan, 232007;The changes and significance of serum electrolyte level in children with serious pneumonia[J];Anhui Medical Journal;2004-06
2 LIN Hong-hua(Department of Pediatrics,Anhui Provincial Children's Hospital,Hefei 230051,China);Effect of intravenous gamma globulin on infants with severe pneumonia[J];Journal of Bengbu Medical College;2007-05
3 WANG Li Jie, LIU Chun Feng, SU Yan QiDepartment of Pediatrics, Second Clinical College, China Medical University, Shenyang 110003 China;Dynamic Changes of Serum TNF-α,IL-1β and IL-6 in Children with Central Nervous System Diseases and the Systemic Inflammatory Response Syndrome[J];Chinese Journal of Contemporary Pediatrics;2002-04
4 Li-Jie WANG, Ya-Juan ZHAO, Chun-Feng LIU. Department of Pediatrics, Second Clinical College, China Medical University, Shenyang 110004, China;Relationship between gastrointestinal dysfunction and childhood critical illness[J];The Chinese Journal of Contemporary Pediatrics;2005-02
5 PENG Shu-Mei, SUN Ping, ZENG Jing, DENG Xue-Mei. Guangdong Province Maternal and Child Health Care Hospital, Guangzhou 510010, China;Cardiac function of children with bronchial asthma[J];Chinese Journal of Contemporary Pediatrics;2006-05
6 SONG Yin-xue, GONG Jun, WU Jian-tao, GENG Juan Department of Gastroenterology, Second Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an 710004, China;Role of bile in rat gastric mucosal injury due to duodenogastric reflux[J];Journal of Southern Medical University;2008-07
7 HU Chuanqi.Department of Paediatric,Taian Maternity and Child Health Hospital,Taian 271000,China;Dopamine combined with dobutamine in the treating the newborn cold injury syndrome complicated by multiple organ damage[J];Clinical Medicine;2009-06
8 WU Li-Juan, YANG Lian-fang (Yiwu Center Hospital of Zhejiang Province, Zhejian Yiwu 322000, China);Assistance of intravenous immunoglobulin in treating severe infant pneumonia[J];Journal of Pediatric Pharmacy;2004-03
9 ZHU Xiao-shi,CHEN Chang-hui(The Sichuan Provincial People's Hospital,Sichuan Chengdu 610072,China);The level of AT-Ш and D-dimer in newborn infants with systemic inflammatory response syndrome[J];Journal of Pediatric Pharmacy;2008-04
10 Xu Manchun, Zhu Huiying (Department of Pediatrics , General Hospital of Guangzhou Command of PLA , GuangZhou, 510010);Clinical significance of systemic inflammatory response syndrome following pneumonia complicated by actue congestive heart failure in infants[J];Guangdong Medical Journal;2001-01
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Li Zhaoshen, Zhan Xianbao, Cui Zhongmin et al. Changhai Hospital, The Second Military Medical University, Shanghai 200433;THE INFLUENCE OF STRESS ON THE ULTRASTRUCTURAL CHANGS IN GASTRIC MUCOSAL ACID BARRIER AND PARIETAL CELLS OF RATS[J];Medical Journal of Chinese People's Liberation Army;1999-06
2 XU Lanping, GUO Nailan, WANG Suqin, et al. Institute of Hematology, People's Hospital, Beijing Medical Univercity, Beijing 100044;ABO incompatible allogeneic bone marrow transplantation[J];CHINESE JOURNAL OF HEMATOLOGY;1999-08
3 TANG Daming 1,ZHANG Hongjin 1, CHEN Dechang 2.1.Emergency Department of Dongyang People's Hospital,Dongyang 322100, Zhejiang China;2.Changzheng Hospital,The Second Military Medical University,Shanghai 200003,China;Effects of stress response on internal environment in critically ill patients[J];Chinese Critical Care Medicine;2002-12
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved