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《Journal of Jilin University of (Medicine Edition)》 1989-05
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Effect of mentha oil on termination of preegnancy in mice

Lu Yifang, Wang Qiujing, Yang Shijie (Department of Pharmacology)  
The effect of mentha oil given by different routes on termination of early pregnancy was observed in mice.Mentha oil (olive oil for the control group) was given intrauterinely on day 6 of pregnancy, and the mice were killed on day 11 of pregnancy.It was observed that early pregnancy in the horn into which mentha oil was given was terminated, with a termination rate of 100%, while it was only 41.76%in the control group.Besides, different doses of mentha oil were injected intramuscularly once daily on day 4 to day 10 of pregnancy. The result showed that implantation was significantly inhibited in all of these three groups, and the effect was dependent upon the dosage. The antiimplan-tatory effect of mentha oil and termination of early pregnancy were probably the result of uterine contraction.Of course, the possibility of direct damage te the decidua can not be excluded.
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