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EFFECT OF PQL ON LIPID PEROXIDATION IN ORGANS OF RATS WITH HEMORRHAGIC SHOCK

Guo Lida, et al(Dept.of Pathophysiol)  
The effect of pretreatment with Panax quinquefolinus Linu (PQL) on contents of lipid peroxides in tissues was studied in hemorrhagically shocked rats. Levels of lipid peroxidation products in the heart, lung, spleen , liver and kidney were measured at 4 hours after bleeding. Levels of lipid peroxides in tissues mentioned above were markedly lower in the pretreated animals than that in the simply hemorrhagically shocked controlled rats.The results showed that PQL might markedly decrease the concentration of tissue lipid peroxides and prevent the cell membrane from damage caused by free radicals. We suggest that PQL may be used as one of the suitable drugs for treatment of shock.
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