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《JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE》 1998-02
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Protection of ginsenosides against O_2~- and H_2O_2 damage to cultured rat cortical neuronal cells

Li Tianwei;Kong Lekai;Xiong Wen,et al(Department of Biochemistry of Norman Bethime University of Medical Sciences Department of Pathophysilolgy of Shandong Medical University)  
Objective: To study the protection of ginsenosides against the free radical damage to cultured rate conical neuronal cells. Methods: The model of O-2 and H2O2 damage to cultured rat cortical neuronal cells was used. Results:Compared with the damaged group,the lactate dehydrogenase (LDH) release decreased significantly (P0. 01) and the neuronal survival rate increased significantly (P0. 01 ) in the protective group of ginsenosides. Conclusion:Ginsenosides can protect the cultured rat conical neuronal cells from free radical damage.
【CateGory Index】: R285
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