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《白求恩医科大学学报》 2001-02
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Study of anti-aging and anti-dementia effects of Rhodosin on aging rats and experimental dementia rats

JIANG Wen-hua,MENG Xiao-ting,HAO Li-ming,CUI Li,DONG Zhi-yong,WANG Shu-lan (Department of Histology and Embryology,School of Basic Medical Sciences,Jilin University,Changchun 130021 China) [  
Objective:To discuss the effects of Rhodosin,the extractant of medical plants named Rhodiola Sachinonsis A.Bor,on aging rats and the model rats of Alzheier′s disease (AD).Methods:Step down and water maze tests were used to determine the content of acetylcholine (Ach) and the activity of acetylcholine transferase (ChAT) of hippocampus,lipid peroxide (LPO) and activity of superoxide dismute (SOD) of the cerebral cortex,and cerebellar cortex and spinal cord were observed respectively.At the same time,the general light microscope and eletron microscope were used to observe the changes in morphology.Results:The Rhodosin as an antioxidant could enhance the content of Ach and the activity of ChAT,reduce the formation of LPO,and increase activity of SOD.The Rhodosin could facilitate metabolism,enhance activity,and inhibit degeneration of aging rat cells.Conclusion:Rhodosin had obvious anti-aging effects on aing rats and also had preventive,protective,anti-dementia effects on experimental dementia.[
【Fund】: 吉林省科委资助!项目 (970 5 5 9- 3)
【CateGory Index】: R285
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【References】
Chinese Journal Full-text Database 10 Hits
1 CHEN Qiu li 1,DENG Wei guo 1* ,WANG Yi 2 (1.Dept.of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun 130021,China;2 .Dept.of Gynecology and Obstetrics,The First Hospital, Jilin University);Effects of Rhodosides on Protein and Lipids Metabolism in Female Rats[J];Journal of Jilin University of (Medicine Edition);2003-04
2 SONG Xiang-fu 1, ZHANG Jing-chun 2, WU Xiao-hui 1 (1. Department of Laboratory Animal, School of Pbulic Health, Jilin University, Changchun 130021,China;2. Department of Laboratory,China-Japan Union Hospital, Jilin University,Changchun 130031, China);Effects of Rhodiola extracts on lipideperoxygen and apoptosis of hepatocytes in aged mice[J];Journal of Jilin University of (Medicine Edition);2004-05
3 CHEN Qiao-ge,ZENG Yuan-shan,TIANG Jiu-yu,QIN Ya-jing,CHEN Sui-jun,ZHONG Zhi-qiang.Division of Neurosciences,Department of Histology and Embryology,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080 China;Experimental research on the sedative and hypnotic effect of Rhodiola rosea[J];Anatomy Research;2008-05
4 ZHANG Yu-zhou;West China School of Public Health,Sichuan University;;Research Progress of the Pharmacological Effects of Rhodiola rosea and Its Application Prospect[J];Journal of Anhui Agricultural Sciences;2015-25
5 LI Hao(Qingdao Kangdien Pharmaceutical Co.Ltd.,Qingdao 266111,China);Progress in pharmacological research of Integripetal rhodiola herb[J];Strait Pharmaceutical Journal;2008-10
6 ZHAO Wei-xing1,JIANG Hong-bo2,WEN Pu-hong1(1.Shanxi Province Key Laboratory of Phytochemistry,Baoji University of Arts and Sciences,Baoji 721013,China;2.Department of Geography and Environmental Engineering, Baoji University of Arts and Sciences,Baoji 721013,China);The Main Chemical Constituents and Pharmacological Effects of Rhodiola Dumulosa Franch[J];Chemistry & Bioengineering;2012-05
7 ;Study progress on mechanism salidroside in nervous system[J];Journal of Regional Anatomy and Operative Surgery;2009-06
8 LUO Min1,SHENG Hui2,WANG Yi-lin3(1.The people'0s hospital of Shenzhen,ShenZhen,518000,China;2.The First Hospital of Jilin University,Changchun,130021;3.Thaditional medical hospital of Tonghua,134000,China);The inhibition of Rhodiola on hepatic carcinoma cells[J];Jilin Medical Journal;2005-12
9 KONG Yu-jie1,SHI Xiao-feng2,MA Jun1,ZHANG Zhi-hong1(1.Gansu College of Traditional Chinese Medicine,Lanzhou 730020,Gansu,China;2.Gansu Academy of Medical Sciences,Lanzhou 730050,Gansu,China);Role of Rhodiola Active Ingredient on Central Nervous System[J];Journal of Liaoning University of Traditional Chinese Medicine;2012-06
10 WANG Ai-ling;QU Wei;LIANG Jing-yu;Department of Natural Medicinal Chemistry,China Pharmaceutical University;;Progresses on chemical constituents and pharmacological activities of Rhodiola L.[J];Strait Pharmaceutical Journal;2014-01
China Proceedings of conference Full-text Database 1 Hits
1 Meng Yucai Zhao Wen Liu Yifeng Feng Lijuan (College of Food Science and Technology,Agricultural University of HeBei,Baoding,Hebei 071000,China);Review on the pharmaceutical study development of Rhodiol L.plant[A];Chinese Society of Agricultural Engineering[C];2007
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Wang Shulan, Wu Shengdong , Wang Yi. Ma Xingyuan , LI Sulian , He Weihui(Dept. of Histoembryol, Dept. of TCM, Second Teaching Hosp, Dept. of Chemistry);STUDY ON THE ANTI-AGING EFFECTS OF RHODOSIN[J];;1991-06
2 Zhang Jun-tian and Saito H~*(Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing;) (~*Faculy of Pharmaceutical Sciences, University of Tokyo, Japan);STUDIES ON SUSCEPTIBILITIES TO THE AMNESTIC EFFECTS OF 12 CHEMICALS ON PASSIVE AVOIDANCE RESPONSES IN MICE: COMPARISON BETWEEN STEP DOWN AND STEP THROUGH TESTS[J];Acta Pharmaceutica Sinica;1986-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Chen Qin, Huang Shifu, Yu Yongjun et al (Anhiu Institute of Materia Medica, Hefei, 230022);Effect of Zhiliwang Capsule on Memory and Acetylcholinesterase Activity in Dementia Mimetic Rats[J];Anhui Medical and Pharmaceutical Journal;1997-01
2 YU Jian ping,ZHANG Cheng wei (The First Affiliated Hospital of Anhui Medical University,Anhui Hefei 230022,China);EFFECTS OF YIZHILING CAPSULE ON LEARNING AND MEMORY ABILITY AND CHOLINESTERASE ACTIVITIES IN MICE MODEL[J];Journal of Anhui Traditional Chinese Medical College;2001-05
3 CHEN Qin,HUANG Shi fu (School of Life Science,Anhui University,Anhui Hefei 230039,China);EFFECT OF NAOYIQING CAPSULE ON LEARNING AND MEMORY ABILITY IN DECLINED MEMORY MICE[J];Journal of Anhui Traditional Chinese Medical College;2001-06
4 Lin Yuanzao Lin Xiangyang (Department of Biochemistry, Guangdong College of Pharmacy, Guangzhou 510224,China) Wan Fada (Guangdong Apllo Pharmaceutic Co,Ltd, Guangzuo 510620,China) Zou Guolin (College of Life Sciences, Wuhan University, Wuhan 430072,China);The Preparation and Biological Activity of Hydrolysate of Swine Brain[J];Amino Acids & Biotic Resources;1999-03
5 JIANG Qing-song,Lü Ya-lin,WU Min-jie,JIANG Ting,ZHANG Jian-jun. Department of Stomatology,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China;Effects of loss of molar teeth on amino acid neurotransmitters in hippocampus of rats[J];Beijing Journal of Stomatology;2008-04
6 Jia Huijuan1 Li Yuan1 Wu Juanjuan1 Zhang Anmin2(1.School of Phydical Education,Shanxi University,Taiyuan Shanxi 030006;2.School of Physical Education,Shanxi University of Finance and Economics,Taiyuan Shanxi 030006);Exercise and the Hippocampal cAMP Research[J];Sport Forum;2010-01
7 Song Qianliu,Zong Ru( Dept.of Pharmacology,The school of Basic Medical Sciences );EffectGASDon learning and memory in the dementia rats induced by hippocampal lesions due to quinolinc acid[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1995-03
8 Li Xi( Second Affliated Hospital of Xi' an medical University, Xi' an );Effect of Nao Er Kang on Learning and Memory Disorders in Model Rats with Alzheimer's Diseases[J];China Journal of Traditional Chinese Medicine and Pharmacy;2001-05
9 Xie Ming, Li Qingye, Bian Yiming, et alBasic College of Beijing University of TCM (Beijing, 100029, China);Research of Action of Shengjing Buxue Decoction (SJBXD) on Anti-ageing and Intensive Intelligence[J];Journal of Chengdu University of Traditional Chinese Medicine;1996-02
10 ZHAO Ji lan, YU Shu guang, ZHOU Qi zhi, et al (赵纪岚,等) Acupuncture, Moxibustion and Tuina College, Chengdu University of TCM (Chengdu, 610075,China);Influence of Acupuncture to the Contents of Neurotransmitter in Central Nervous System of Senile Rats and Mice[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1999-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 SONG Xu-hong, ZHANG Yue-ming, DENG Hong(Department of Occupational Health, Xinjiang Medical University, Urumqi 830054, China);IN VITRO ANTITUMOR EFFECTS OF PLEUROTAS SAPIDUS[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-02
2 JIN Xin et al (Agronomy Department of Agronomy College,Yanbian University,Longjing, Jilin 133400);Comparative Study on Floral Organ Morphology of Different Sexual Plants in Rhodiola sachalinensis A. Bor.[J];Journal of Anhui Agricultural Sciences;2007-28
3 CHENG Zi-yu et al (College of Pharmacy,Lanzhou University,Lanzhou,Gansu 730000);Study on the Extraction Technology of Salidroside from the Root of Rhodiola rosea L.under High Pressure[J];Journal of Anhui Agricultural Sciences;2008-19
4 LI Mei-shan et al(Department of Agronomy,Agricultural College,Yanbian University,Longjing,Jilin 133400);Comparison Study on the Morphologic Characters of Different Sexual Rhodiola sachalinensis A.Bor[J];Journal of Anhui Agricultural Sciences;2009-04
5 LIU Jing et al (Department of life science, Shaanxi Institute of Education , Xi′an, Shaanxi 710061);Study on the Reducing Blood Lipid and Antioxidition Effects of Flavonoids from Eucommia ulmiodes Olirer Leaves[J];Journal of Anhui Agricultural Sciences;2010-11
6 DAI Chun-min et al (Military Physical Research Department,Jilin Agricultural University,Changchun,Jilin 130118);Experimental Research on the Anti-fatigue Function of Rhodiold sachlinensis A·Bor in Mice[J];Journal of Anhui Agricultural Sciences;2010-30
7 MA Hong-bo et al(Department of Nutrition,Jilin Medical College,Jilin,Jilin 132013);Extraction of Polysaccharide form Mulberry Leaf by Sodium Hydroxide and Content Determination[J];Journal of Anhui Agricultural Sciences;2011-03
8 ZHENG Guo-qiang et al(College of Food Engineering and Biotechnology,Tianjin University of Science and Technology,Tianjin 300457);Study on Comparison of the Immune of Thymus and Spleen between Male and Female Mice[J];Journal of Anhui Agricultural Sciences;2011-16
9 ZHANG Li-xia et al(School of Life Sciences,Daqing Normal College,Daqing,Heilongjiang 163712);Effects of Different Extraction Methods on Antioxidant Activity of Inonotus obliquus Polysaccharides[J];Journal of Anhui Agricultural Sciences;2012-10
10 LU Jing-tao, WEI Wei,CHEN Min-zhu (Institute of Clinical Phurrnacology,Anhui Medical University,Hefei 230032);A preliminary tudy on antitumor activity of artimisinine[J];Anhui Medical and Pharmaceutical Journal;2007-01
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 LIU Yu-qi(College of Sciences,Jiujiang University,Jiujiang,Jiangxi 332000);Research Progress on Plant Rhodiola rosea's Function on Degenerative Diseases of the Nervous System[J];Journal of Anhui Agricultural Sciences;2010-20
2 YANG Yong-jie et al (Agricultural College,Yanbian University,Yanji,Jilin 133002);Study on Combined Hypoglycemic Effect of Wild Taraxacum mongolicum and Rhodiola sachalinensis on Diabetic Mice[J];Journal of Anhui Agricultural Sciences;2011-02
3 GONG Gang-ming et al (School of Perfume and Aroma Technology,Shanghai Institute of Technology,Shanghai 200235);Optimization of Ultrasonic Extraction Process of Tannins from Rhodiola crenulata(Hook.f.et Thoms.)H.Ohba[J];Journal of Anhui Agricultural Sciences;2011-06
4 HUANG Ren-fu,WU Zhou-he,HAN Chun-cheng,ZHU Yi-ting(College of Bioengineering,Hubei University of Technology,Wuhan 430068,China);Optimization of Extraction Technology of Total Flavonoids from Rhodiola sacra by Response Surface Analysis[J];Amino Acids & Biotic Resources;2010-01
5 LU Jing-lan1,XU Ming-zi2,LIU Xian-hu2,LI Mei-shan2,AN Jin-hua2(1.College of Science,Yanbian University,Yanji,Jilin 133002;2.College of Agriculture,Yanbian University,Yanji,Jilin 133002);The Characteristics of Distribution of Essential Amino Acids for Rhodiola sachalinensis A.Bor[J];Northern Horticulture;2011-22
6 Yang Xianling Red Cross Taiwangnese Hospital,Xiangshan County,Zhejiang Province(315731);Review on Chinese Medicine Treating Senile Dementia[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-01
7 ;Measurement of vitamin C in dark color vegetables and fruits by electric potential titration[J];Journal of Jilin University of (Medicine Edition);2004-05
8 WANG Jing-ye,YU Rong,YAO Ming-hui(Department of Pharmacology,Shanghai Medical College,Fudan University,Shanghai 200032,China);Protective effects and mechanisms of salidroside on cerebral ischemia-reperfusion injury[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-03
9 ZHAO Jin,LAI Ji-xiang,HE Cong-fen,ZHAO Hua,YANG Ya-dong,DONG Yin-mao(Beijing Key Laboratory of Plant Resources Research and Development,Beijing Technology and Business University,Beijing 100048,China);Extraction technology of active ingredients in plant Rhodiola and its function in cosmetics[J];China Surfactant Detergent & Cosmetics;2009-06
10 LIU Xiao-mei, DONG Mei-rong, WANG Jing-xia. Suzhou Health College, Suzhou 215009 China;Effect of Rhodioside on GAP-43 expression following focal cerebral ischemia / reperfusion in rats[J];Anatomy Research;2009-04
China Proceedings of conference Full-text Database 4 Hits
1 ;Review of quality control of Oral Liquid of Radix Bupleuri[A];[C];2009
2 Meng Yucai Zhao Wen Liu Yifeng Feng Lijuan (College of Food Science and Technology,Agricultural University of HeBei,Baoding,Hebei 071000,China);Review on the pharmaceutical study development of Rhodiol L.plant[A];Chinese Society of Agricultural Engineering[C];2007
3 LI Ying;WangXing-fang;LiJun;ChenLi-ting;XiaoWen;Department of Life Sicence,Gansu Agricultural University;Department of Science,Gansu Agricultural University;;Studies of the Effective Ingredient and salidroside content of Rhodiola tangutica[A];[C];2013
4 Wu Hao;DI Liu Qing;Dan Jin Jun;Kang An;Zu Qiang;Zhou Wei;ZOU Jia Shuang;Li Chen;Yi Wei;;Rat plasma Salidroside UPLC-MS method for detection and bioavailability studies[A];[C];2013
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