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《Journal of Jilin University of (Medicine Edition)》 2003-04
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Protective Effect of Rg_2 on Myocardium of Dog with Acute Cardiogenic Shock

CUI Xin ming 1,LI Yan ru 1,LU Wen wei 2,CUI Li 1,LIU Jie 2 TIAN Jian ming 3,LI Long yun 3,YE Jin mei 3,ZHANG Zhi wei 3,DOU Ying △ (1. Dept.of Electron Microscopy,School of Basic Medical Sciences, Jilin University, Changchun 130021,China;2. Dept.of Pharmacology,School of Basic Medical Sciences, Jilin University;3. Institute of Chinese Traditional Medicine and Herbs,Jilin Province)  
Objective: To investigate the effect of Rg 2 on oxygen metabolism of dog with acute cardiogenic shock and ultrastructure of myocyte. Methods: Models of acute cardiogenic shock were made by ligating left anterior descending branch of coronary artery(LAD). Rg 2 2,1 mg·kg -1 were injected respectively in order to observe the effects on oxygen metabolism of dog with acute cardiogenic shock. Results:iv. Rg 2 could reduce the exponent of oxygen consuming of myocardium and rate of oxygen intake of myocardium comparing with control group; ultrastructure of myocyte turned to normal. Conclusion:Rg 2 has therpaeutical effects on dogs with acute cardiogenic shock.
【Fund】: 国家科委工程基金资助课题 (95 1 0 35 )
【CateGory Index】: R285
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