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《Journal of Jilin University of (Medicine Edition)》 2003-06
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Change of HBV DNA Level in the Sera of Patients with Chronic Viral Hepatic Disease and its Clinical Significance

JIN Zhen jing 1, CHI Bao rong 2 (1. Dept.of Digestive Medicine, The Second Hospital, Jilin University, Changchun 130041, China;2. Dept.of Digestive Medicine, The First Hospital, Jilin University)  
Objective: To observe the change of HBV DNA level in the sera of patients with chronic viral hepatic disease and its clinical significance. Methods:The amount of HBV DNA in the sera of patients with chronic hepatitis B (CHB), chronic severe hepatitis B (CSHB) and hepatic B cirrhosis (HBC) were measured with FQ PCR. Results: The level of HBV DNA in CSHB group was significantly lower than those in CHB and HBC groups ( P 0.01). The bilirubin level in the sera of patients with chronic viral hepatic disease of different clinical types had a inverse relationship with the level of HBV DNA. Conclusion: The patients with chronic viral hepatic disease had an unbalance on the regulation and control of immunologic function. The level of HBV DNA as well as the bilirubin level in the sera of patients can reflect the necrosis degree of liver cells.
【Fund】: 吉林省计经委资助课题 (2 0 0 0 - 9)
【CateGory Index】: R512.6
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Chinese Journal Full-text Database 1 Hits
1 ZHANG Ling-ling~(1,2),MENG Xiang-wei~(1*),SUN Xun~3,KONG De-xia~1,SUN Yan~1(1.Department of Digestive Medicine,First Hospital,Jilin University,Changchun 130021,China;2.Department of Digestive Medicine,People's Hospital,Guizhou Province,Guiyang 550002,China;3.Department of Pathology,First Hospital,Jilin University,Changchun 130021,China);Genotypes of hepatitis B virus in Changchun[J];Journal of Jilin University(Medicine Edition);2006-06
Chinese Journal Full-text Database 2 Hits
1 SHI Dongmei (Department of Infectious Diseases, Ruijin Hospital, SSMU, Shanghai 200025);Significance of Detection of Serum HBV DNA in Hepatitis B Patients[J];Acta Universitatis Medicinalis Secondae Shanghai;2000-06
2 ZHOU Xiaohui *, GAO Zhiliang, YAO Jilu. * Department of Infectious Diseases, the Second Affiliated Hospital of Medical College of Shantou University, Shantou 515031;Relationship between HBV DNA serum level and acute exacerbation of the disease in chronic hepatitis B patients[J];Chinese Journal of Experimental and Clinical Virology;1999-04
Chinese Journal Full-text Database 10 Hits
1 LI Lin et al (College of Animal Science and Technology,Jiangxi Agricultural University,Nanchang,Jiangxi 330045);Report on the Diagnosis and Treatment of a Case of Porcine Peritonitis Caused by Escherichia coli[J];Journal of Anhui Agricultural Sciences;2008-36
2 REN Zi-li et al(Faculty of Animal Science,Tibet Agricultural and Animal Husbandry College,Linzhi,Tibet 860000);Isolation and Culture of Fetal Fibroblasts of Tibetan Yellow Cattle[J];Journal of Anhui Agricultural Sciences;2011-24
3 ZHAO Jing Wu, WU Jin Feng (Hefei Infecious Diseases Hospital 230022);Changes of serum HA in patients with chronic hepatitis B after treatment with DANSHEN[J];Anhui Medical and Pharmaceutical Journal;2001-01
4 ZHAO Jie-qing~(1),Xu Jian-ming~(2),MEI Qiao~(2),et al(1.The Renmin Hospital of Huaining County,Huaining 246121;2.Dept of Gastroenterology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);Clinical factors influencing the therapeutic response to diuretic treatment of ascites in liver cirrhosis[J];Anhui Medical and Pharmaceutical Journal;2006-10
5 XU Kui,YAN Zhao hong,WANG Hui,ZHOU Ming lin,ZHANG Wei,NI Yong (Wuhu Hospital of Traditional Chinese Medicine,Anhui Wuhu 241000,China);32 CASES OF LOW-GRADE JAUNDICE DUE TO CHRONIC HEPATITIS AND HEPATOCIRRHOSIS TREATED WITH WENYANG QUYU HUATAN DECOCTION[J];Journal of Anhui Traditional Chinese Medical College;2002-02
6 GAO Hui, ZHOU Da-qiao, XIONG Yi-qun, HE Jin-song, TONG Guang-dong, PENG Li-sheng (Hepatopathy Institute,Shenzhen Hospital of Traditional Chinese Medicine Attached to Guangzhou University of Traditional Chinese Medicine ,Guangdong Shenzhen 518033,China);Experimental Study on Treatment of Hyperlipidemic Fatty Hepatitis with Formula of Blood-activating and Phlegm-and Dampness-relieving[J];Journal of Anhui Traditional Chinese Medical College;2003-04
7 SUN Xiao jie,ZHANG Guo qun (Department of Infectious Diseases,Affiliated Hospital of Bengbu Medical College,Anhui 233004,China);The analysis of the status of fatty liver and related factors in cadres of Bengbu city[J];Journal of Bengbu Medicine College;2003-01
8 Chen Xiaonan, Zhu Xi, Fang Zhiming Medical School of Hangzhou Teachers College, Hangzhou(310012);The Effect of Radix Salvia Mitorrhiac Injection on the Blood Serum TNF of Alcoholic Liver Injury Rat[J];Journal of Zhejiang College of Tcm;2004-03
9 Zhu Xuxia Disease Prevention and Control Center of Wuyi County, Zhejiang Province(321200);Therapeutic Effect of Integrated Traditional Chinese and Western Medicine on Hypohepatia Induced by Antitubercular Drugs[J];Journal of Zhejiang University of Traditional Chinese Medicine;2009-03
10 SUN Xiao-li, CHU Jian-guo, CHEN Pan-zao (Department of Nuclear medicine, General Hospital of Air Force, PLA, Beijing 100036, China);Study of Angiotensin Ⅱ(AT-Ⅱ)Level Fluctuation in Patients with Chronic Hepatic Disease Pre-and-post Interventional Therapy[J];Labeled Immunoassays and Clinical Medicine;2001-02
China Proceedings of conference Full-text Database 3 Hits
1 Pang Yongli Li Laisheng Liu Yongqing,Department of Infectious Diseases,Ordos No.2 Hospital,Ordos,,Inner Mongolia,017000 China;An analysis on the plasma exchange treatment with the artifical liver support system on hepatits gravis[A];[C];2004
2 Wu Ping Gao Dongchen Liu Jian Zhou Delu Zhang Dong Wang Yu Department of General Surgery,Affiliated Beijing Friendship Hospital,Capital University of Medical Sciences,Beijing 100050.;The experimental study of endotoxemia and blood perfusion for pig in orthotopic liver transplantation[A];[C];2004
3 WU Jie,YU Jian-er,ZNANG Xin-guang (Affiliated Hospital of TCM to Shanghai University of TCM,Shanghai 200071,China);Clinical Observation on Pediatric Mycoplasma Pneumonia Treating with Integrative Chinese and Western Therapy[A];[C];2008
Chinese Journal Full-text Database 3 Hits
1 XIA Guoliang *, Omana V Nainan, JIA Zhiyuan,et al. *Institute of Virology, Chinese Academy of Preventive Medicine, Beijing 100052,China;Characterization and distribution of hepatitis B virus genotypes and subtypes in 4 provinces of China[J];Chinese Journal of Epidemiology;2001-05
2 GUO Yabing *, HOU Jinlin, DAI Wei, et al. *Department of Infectious Disease, Nanfang Hospital, Guangzhou 510515;Establishment of the consensus sequence of hepatitis B virus prevailing in the mainland of China[J];CHINESE JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY;1999-03
3 LIN Xu,XU Xiao,ZHENG Da-li,LIN Jian-yin. Research Center of Molecular Medicine,Fujian Medical University,Fuzhou 350004,China;Structural analysis of 22 full-length hepatitis B virus genomes isolated from patients with hepatocellular carcinoma[J];Chinese Journal of Oncology;2004-04
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 FENG Ying,GU Rong-fang (TCM Department,Medical School of Jingangsan University,Ji an 343000,China);The review of the relationship between HBV genotype,clinical research and new therapeutic countermeasures of TCM[J];Journal of Jinggangshan University;2008-03
2 OUYANG Shaoqing,ZHANG Ming;An Academic Analysis on the "Primitive Music" in the National Singing Contest for the Youth[J];Journal of Jinggangshan University;2008-06
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Zhang Zhi, Luo Kangxian, Liang Zhisen Department of Infectious Diseases, Nanfang Hospital, First Military Medical, Guangzhou 510515;HBV replication as a cause of reactivity of Chronic liver diseases[J];ACAD J ISI MED COLL PLA;1994-01
2 Huang Huafang;Xiong Kaijun;Zong Linglan et al(Department of Infectious Diserse,Union Hospolal,Tongji Medical University,Wuhan 430022);Discussion on the Relationship between the serum HEV Replication Marks and Hepatic Pathological Changes in the Chronic Hepatits B of High Replication Type[J];VIROLOGICA SINICA;1994-01
3 Sun Wensheng, Gao Fengguang, Cao Yinglin, et al. Shandong Medical University, Jinan 250012;A study on integration of HBV DNA and HBx subfragment in hepatocellular carcinoma[J];CHINESE JOURNAL OF INFECTIOUS DISEASES;1997-02
4 Zhang Fuchun,Wu Wanfen,Dong Huiqing,et al.Guangzhou 8th People's Hospital ,Guangzhou 510060;Detection of serum HBV DNA by quantitative PCR and its clinical application[J];CHINESE JOURNAL OF INFECTIOUS DISEASES;1997-01
5 LU Zhimeng, YAO Guangbi, WU Xianghui, et al. Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025;A comparative trial of thymosin α1 vs. thymosin α1 combined with interferon α1b in the treatment of chronic hepatitis B[J];CHINESE JOURNAL OF INFECTIOUS DISEASES;1999-01
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