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《Journal of Jilin University of (Medicine Edition)》 2004-01
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Changes of POD activities in the key organs in adult rats with diabetes

LI Xiao mei,LU Yan juan,LI Xiao lin * (Experimental Center of Biochemistry and Molecular Biology,School of Basic Medical Sciences, Jilin University, Changchun 130021,China)  
Objective To study the changes of peroxidase (POD) activities in the key organs in adult rats with diabetes Methods Thirsty Wistar rats for 90 days were divided into three groups:control group (C), diabetes group treated with insulin (ID) and diabetes group (D), 10 rats in each group The POD activities were determined by using guaiacol colorimetric method Results The activities of POD in the hearts, sleeps, and lungs in group D and group ID were decreased obviously ( P0 05, P 0 01), compared with control group; the POD activities in the hearts and lungs in group D were apparently lower than those of group ID ( P0 05, P0 01 ) Conclusion The POD activities are decreased in rats with diabetes and insulin can partly recover POD activities in the key organs
【Key Words】: peroxidase/metabolism diabetes mellitus/enzymology guaiacol colorimetric method disease models animal
【Fund】: 国家自然科学基金资助课题 (39870 31 3)
【CateGory Index】: R587.1
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