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《Journal of Jilin University of (Medicine Edition)》 2004-06
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Influences of stationary magnetic fields on contents of LPF in brain,heart ,kidney, and GSH-Px in heart, kidney, and thymus of old mice

FU Yan 1,LIANG Lu-guang 1,YAO Shu-ren 2,LI Xiao-lin 3,LI Xiao-mei 3,LU Yan-juan 3(1.Physics Teaching Center, Jilin University,Changchun 130021,China;2. Department of Anatamy, School of Basic Medical Sciences,Jilin University, Changchun 130021,China; 3.Departmentof Biochemistry, School of Basic Medical Sciences, Jilin University, Changchun 130021, China)  
Objective To study the influences of stationary magnetic fields on the contents of lipofuscin (LPF) in brain,heart, and kidney and the contents of GSH-Px in heart,kidney, and thymus of old mice.Methods Twenty female old mice were randomly divided into experimental group and control group. The mice in the experimental group were then put into a metal box where magnetic induction was 200 mT. They were exposed to the magnetic field one hour every day for 30 days running. Results The content of LPF in brain of old mice in experimental group ((0.160±0.024) μg·g -1 ) was reduced remarkably (Ρ0.05), compared with the control group ((0.304± 0.061) μg·g -1 ). But there were no significant differences of the contents of LPF in heart and kidney ((0.082± 0.009) and (0.329± 0.024) μg·g -1 ) (P0.05) in experimental group, compared with the control group ((0.092±0.011) and (0.382±0.033) μg·g -1 ). The activities of GSH-Px in heart, kidney, and thymus of old mice in experimental group ((9.63±1.52),(30.68±4.50),and (96.72± 10.94) NU·mL -1 ) were increased remarkably (P0.05 or P0.01), compared with control group ((7.63±1.48),(24.09±4.49),and (85.68± 7.122) NU·mL -1 ). Conclusion In the stationary magnetic fields (20 mT), the contents of LPF in organs are reduced, free radicals are resisted and the activity of anti-oxide ferment is increased.
【Fund】: 卫生部科学研究基金资助课题 (3A3930 0 6 30 39)
【CateGory Index】: R35
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