Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Jilin University of (Medicine Edition)》 2005-04
Add to Favorite Get Latest Update

Protective effects of egg-milk with MT on mice damaged by irradiation

ZHAO Hong-guang~1, WANG Zhi-cheng~1, DU Xiang~1, LU-Zhe~1,JIANG Xiao-yan~1,SHI Jing-yu~2, GONG Shou-liang~1(1. MH Radiobiology Research Unit, School of Public Health, Jilin University, Changchun 130021, China;2. Haerbin Chunyuan Biotechnology Development Co.,LTD, Haerbin 150036,China)  
Objective To explore the protective effects of egg-milk with metallothionein (MT) on mice damaged by irradiation. Methods After the mice were irradiated with 2.5 Gy (12.5 mGy·min~-1) X-rays, they were fed with egg-milk with MT for 14 days. The level of WBC in peripheral blood, lymphocyte proliferation rate, DNA content in marrow cells, malondiadehyde (MDA) levels and the activities of antioxidant enzymes (SOD, CAT and GSH-Px) in liver and kidney were measured. Results After the irradiated mice were fed with egg-milk with MT, especially in the egg-milk with MT of mild and high doses plus irradiation groups, the WBC number, lymphocyte proliferation rate and DNA content of marrow cells in the mice were significantly higher than those in the irradiation group (P0.01), at the same time, the percentage of thymocyte G0/G1 phase of these mice were significantly lower than that of the irradiation group (P0.01), and the percentage of thymocyte S and G2/M phase were significantly higher than those in the irradiation group (P0.01 or P0.05). Compared with the normal control, MDA levels in liver and kidney of the irradiation group increased significantly (P0.01 or P0.05), and the antioxidant enzyme activities of SOD, CAT and GSH-Px decreased significantly (P0.01 or P0.05). While in the egg-milk with MT plus irradiation groups, the MDA contents were significantly lower than those in the irradiation group (P0.01) and the activities of SOD, CAT and GSH-Px were significantly higher than those in the irradiation group (P0.01 or P0.05). Conclusion The egg-milk with MT has protective effects on mice injuried by irradiation.
【Fund】: 吉林省科技厅资助课题(9630031)
【CateGory Index】: R151
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 9 Hits
1 HU Xiu-li~1,RONG Hui~2,LIU Zhong-ying~1,LI Cai~ 1* (1.Department of Analyticl Biochemistry, Institute of Frontier of Medical Sciences,Jilin University, Changchun 130021,China;2.Jilin Entry-Exit Inspection and Quanrantine Burean,Changchun 130062,China);Effects of MT egg-milk powder on trace elements in brain and femur of lead poisoning rats[J];Journal of Jilin University(Medicine Edition);2006-05
2 ZHAO Hong-guang1,GUO Wei1,LI Yan-bo1,WANG Zhi-cheng1,XU Song-bai2,LIU Shu-chun1,SHI Jing-yu3,GONG Shou-liang1(1.MH Radiobiology Research Unit,School of Public Health,Jilin University,Changchun 130021,China;2.Department of Neurosurgery,First Hospital,Jilin University,Changchun 130021,China;3.Harbin Chunyuan Biotechnology Development Co.Ltd,Haerbin 150036,China);Therapeutic effects of egg-milk with metallothionein on H-22 hepatoma in BALB/c mice[J];Journal of Jilin University(Medicine Edition);2007-03
3 ZHAO Hong-guang1,2,XU Song-bai3,LI Yan-bo1,GUO Wei1,WANG Zhi-cheng1,SHI Jing-yu4,GONG Shou-liang1(1.Key Laboratory of Radiobiology,Ministry of Health,School of Public Health,Jilin University,Changchun 130021,China;2.Department of Nuclear Medicine,First Hospital,Jilin University,Changchun 130021,China;3.Department of Neurosurgery,First Hospital,Jilin University,Changchun 130021,China;4.Harbin Chunyuan Biotechnology Development Co.Ltd.,Harbin 150036,China);Preventive effects of egg-milk with MT on H-22 hepatocellular carcinoma in BALB/c mice[J];Journal of Jilin University(Medicine Edition);2007-05
4 HU Xiu-li1,LI Cai2,MIAO Chun-sheng2,SUN Bo2,SHI Jing-yu3(1.Department of Analytical Biochemistry,Institute of Frontier Medical Sciences,Jilin University,Changchun 130021,China;2.Department of Pathology,Institute of Frontier Medical Sciences,Jilin University,Changchun 130021,China;3.Harbin Chunyuan Biotechnology Development Co.Ltd.,Harbin 150036,China);Effects of MT egg-milk powder on lipid metabolism and serum zinc and copper levels in diabetic rats[J];Journal of Jilin University(Medicine Edition);2007-05
5 DING Guirong GUO Guozhen(Department of Radiation Medicine,Faculty of Preventive Medicine,Fourth Military Medical University,Xi'an 710032,China);Advances in research of radioprotectant[J];Journal of Radiation Research and Radiation Processing;2007-06
6 WANG Yi1,XU Song-bai2,GU Bin-bin1,HUANG Wei1,ZHAO Hong-guang3,SHI Jing-yu4(1.First Hospital,Wenzhou Medical College,Wenzhou 325027,China;2.First Hospital,Jilin University,Changchun 130021,China;3.Harbin Chunyuan Biotechnology Development Co.LTD,Haerbin 150036);Research on the protective effects of egg-milk with metallothionein on acute hepatic injury in rats induced by carbon tetrachloride[J];Shanghai Journal of Preventive Medicine;2008-11
7 LUAN Xin-hong,SHI Jiao,LIU Mei,NING Zhi-li,L Qiu-feng,JIANG Li (Animal Science and Verterinary Medicine College,Shenyang Agricultural University,Shenyang 110866,China);Effect of Atrazine on Antioxidant Function and Alterations of Hepatic Tissue in Rats[J];Journal of Shenyang Agricultural University;2010-05
8 YAO Zhao-yang1,ZHU Wen-wen2,NIU Jing-yuan1,et al(1.School of basic medicine Xinxiang medical college,Xinxiang 453003;2.College of Food & Bioengineering Henan university of science and technology,Luoyang 471003;3.Department of life and technique Xinxiang medical college;4.College of life science Henan normal university: Xinxiang 453003,China);The medical research progress of metallothionein[J];Studies of Trace Elements and Health;2007-03
9 WANG Lei1,WEN Cheng-rong3,WANG Yu-e2,XIONG Shan-bai1,HU Xiao-bo1,3 (1College of Food Science and Technology,Huazhong Agricultural University,Wuhan 430070 ;2Hubei Provincial Center for Disease Control and Prevention,Wuhan 430079;3 College of Food Science,Fujian Agriculture and Forestry University,Fuzhou,350002,China);STUDY ON THE EFFECT OF CRUDE PEPTIDE FROM RAPE POLLEN ON ANTI-RADIATION DAMAGE[J];Acta Nutrimenta Sinica;2010-01
【Citations】
Chinese Journal Full-text Database 3 Hits
1 ;Antioxidant damage function of metallothionein and its mechanism[J];Journal of Jilin University of (Medicine Edition);2005-02
2 WEN Jing, ZHAO Jian, BI Xin, JIN Zong lian, JIN Rei yuan 1, RU Bing gen 1 (Department of Biochemistry, College of Applied Science and Humanities, Beijing Union University, Beijing 100083; 1Life Science Colla;THE EXPERIMENTAL STUDY ON ANTI RADIATION EFFECT OF METALLOTHIONEIN[J];Acta Nutrimenta Sinica;2001-01
3 Wei Tao;Tang Fenfang;Wang Weiping;Gao Zhaolan;Jin Zonglian (College of Applied Science and Humanities of BUU Beijing. 100083);Study of Antioxidation and Enhancing Immunity Effect of Metallothioneins[J];CHINA FOOD ADDITIVES;2000-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Rui-juan,ZHANG Chong-xi(Marine College of Shandong University,Weihai,Shandong 264209);Advances in Studies of Antioxidative Materials from Marine Living Things[J];Northern Horticulture;2010-09
2 HU Xiu-li~1,RONG Hui~2,LI Cai~(1*),SHI Jing-yu~3,WANG Zhe-bin~4(1.Department of Analytical Biochemistry Institute of Frontier Medical Sciences,Jilin University,Changchun 130021,China;2.Jilin Entry-Exit Inspection and Quanrantine Burean,Changchun 130062,China;3.Haerbin Chunyuan Biological Technological Development Limited Company,Haerbin 150001,China;4.Haerbin Hamu Chunyuan Biological Technological Development Limited Company,Haerbin 150069,China);Lead-excretion of MT egg-milk power in lead-treated rats[J];Journal of Jilin University(Medicine Edition);2006-04
3 HU Xiu-li~1,RONG Hui~2,LIU Zhong-ying~1,LI Cai~ 1* (1.Department of Analyticl Biochemistry, Institute of Frontier of Medical Sciences,Jilin University, Changchun 130021,China;2.Jilin Entry-Exit Inspection and Quanrantine Burean,Changchun 130062,China);Effects of MT egg-milk powder on trace elements in brain and femur of lead poisoning rats[J];Journal of Jilin University(Medicine Edition);2006-05
4 YAN Yan1,JI Zhihui1,DU Wei1,DONG Jin1,ZHANG Chunlan1,CHEN Jian2,YAN Changjiang3(1.Beijing Tongzhou District Municipal Sciences and Technology Commission,Beijing 101101,China;2.Beijing Tongzhou District Plant Protection Station,Beijing 101117,China;3.College of Animal Sciences and Technology,Northeast Agricultural University,Harbin 150030,China);Research progesses of applied metallothionein[J];Journal of Northeast Agricultural University;2010-07
5 Ren Jiong,Li Rong,Liu Jing,Chen Shi-guo,Zou De-xing,Hao Yu-hui,Su Yong-ping(State Key Laboratory of Trauma, Burns and Combined Injury,Institute of Combined Injury,College of Military Preventive Medicine,Third Military Medical University;Chongqing,400038,China);Detoxifying effect of metallothionein and zinc on acute depleted uranium poisoning in rats[J];Acta Academiae Medicinae Militaris Tertiae;2010-04
6 Tan Qiong, Zhang Bin;Metallothionein and animal emergency[J];Feed Industry;2007-07
7 DING Guirong GUO Guozhen(Department of Radiation Medicine,Faculty of Preventive Medicine,Fourth Military Medical University,Xi'an 710032,China);Advances in research of radioprotectant[J];Journal of Radiation Research and Radiation Processing;2007-06
8 YU Duo-wei, YUAN ShengLife Science College, Nanjing Normal University, Nanjing 210097, China;Damage Analyse of X-Ray Radiated Cellobiohydrolase Ⅱ Molecule from Trichoderma Viride[J];Spectroscopy and Spectral Analysis;2007-04
9 JIN Liming1),YANG Yan2),LIU Wanshun2),HAN Baoqin2),TIAN Wenjie1),FAN Shengdi1)1)College of Life Science, Dalian Nationalities University, Dalian 116600 2) College of Marine Life Science, Ocean University of China, Qingdao 266003;Protective effects of D-glucosamine against carbon tetrachloride-induced liver damage in mice[J];Journal of Zhengzhou University(Medical Sciences);2009-01
10 LIU Zhi-yong~1,WEI Guo-lin~2(1.Jiangxi Labor Sanitation & Occupational Disese Prevention and Treatment Institute,Jiangxi Nanchang 330006 PRC)2.Jiangxi Nanchang Kelin Biotechnology Co.Ltd,Jiangxi Nanchang 330029 PRC);Development of Metallothionein Studies[J];Jiangxi Science;2004-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIU Zhen-jiang et al(Tianjin School,Engineering University of PLA Navy,Tianjin 300450);Prospect for Development and Exploitation of Insect Food[J];Journal of Anhui Agricultural Sciences;2005-09
2 SI You-bin,MENG Xue-mei(School of Resources and Environment,Anhui Agricultural University,Hefei 230036);Advance in environmental fate and ecological remediation of the herbicide atrazine[J];Journal of Anhui Agricultural University;2007-03
3 WANG Lai-Cheng,WANG Jin-Xing **,ZHAO Xiao-Fan,CAI YingSchool of Life Sciences,Shandong University,Jinan 250100, China;Recombinant expression in E. coli,purification and polyclonal antibody preparation of a defensin from the housefly[J];Acta Zoologica Sinica;2005-02
4 JI Qingzhou\ WANG Libo\ ZHOU Yuan\ RU Binggen (Department of Biochemistry and Molecular Biology,College of Life Sciences,Peking University National Laboratory of Protein Engineering,Beijing,100871,China);Study on Competition Reaction and Replacement Reaction of Metallothioneins with Lead Ion[J];ACTA SCICENTIARUM NATURALUM UNIVERSITIS PEKINESIS;2000-04
5 XU Jiaxi\ MIAO Ping\ SONG Yanling\ JIN Sheng (College of Chemistry and Molecular Engineering,Peking University,Beijing,100871);Studies on Peptides and Polysaccharides in Several Pollens[J];ACTA SCICENTIARUM NATURALUM UNIVERSITIS PEKINESIS;1999-02
6 JIN Guang hui 1,LIU Shu zheng 1,LIU Yang 1,LI Xiao kun 2,MA Xing yuan 3 (1. MH Radiobiology Research Unit,Jilin university,Changchun 130021 China; 2. Institue of Bioengineering,Jinan University; 3. Dept.of Organic Chemistry,Jinlin university);Study on protective mechanism of PT,VitE and VitC from skin damage induced by ultraviolet radiation[J];Journal of Norman Bethune University of Medical Science;2002-01
7 ;Antioxidant damage function of metallothionein and its mechanism[J];Journal of Jilin University of (Medicine Edition);2005-02
8 CHEN Yue 1, WANG Bao-gui 2, ZHANG Gui-ying 2, YAN Wei-qun 3 (1. Department of Pharmacy Analysis,School of Pharmacy,Jilin University,Changchun 130021,China; 2. Department of Nutrition and Food Hygiene,School of Public Health,Jilin University, Changchun 130021,China; 3. Department of Biochemistry,Institute of Frontier Medical Sciences,Jilin University, Changchun 130021,China);Protective effects of acanthopanax senticosus saponins on mice with irradiation damage induced by X-rays[J];Journal of Jilin University of (Medicine Edition);2005-03
9 HU Xiu-li~1,RONG Hui~2,LI Cai~(1*),SHI Jing-yu~3,WANG Zhe-bin~4(1.Department of Analytical Biochemistry Institute of Frontier Medical Sciences,Jilin University,Changchun 130021,China;2.Jilin Entry-Exit Inspection and Quanrantine Burean,Changchun 130062,China;3.Haerbin Chunyuan Biological Technological Development Limited Company,Haerbin 150001,China;4.Haerbin Hamu Chunyuan Biological Technological Development Limited Company,Haerbin 150069,China);Lead-excretion of MT egg-milk power in lead-treated rats[J];Journal of Jilin University(Medicine Edition);2006-04
10 ZHAO Hong-guang1,2,XU Song-bai3,LI Yan-bo1,GUO Wei1,WANG Zhi-cheng1,SHI Jing-yu4,GONG Shou-liang1(1.Key Laboratory of Radiobiology,Ministry of Health,School of Public Health,Jilin University,Changchun 130021,China;2.Department of Nuclear Medicine,First Hospital,Jilin University,Changchun 130021,China;3.Department of Neurosurgery,First Hospital,Jilin University,Changchun 130021,China;4.Harbin Chunyuan Biotechnology Development Co.Ltd.,Harbin 150036,China);Preventive effects of egg-milk with MT on H-22 hepatocellular carcinoma in BALB/c mice[J];Journal of Jilin University(Medicine Edition);2007-05
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 YUAN Yi-Ming① WANG Gui-Ling① LI Jia-Le①②(① Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources,Shanghai Ocean University,Ministry of Education,Shanghai 201306;② Aquaculture Division,E-Institute of Shanghai Universities,Shanghai 201306,China);Cloning and Sequence Analysis of Metallothionein Gene in Hyriopsis cumingii[J];Chinese Journal of Zoology;2009-05
2 Ren Jiong,Li Rong,Liu Jing,Chen Shi-guo,Zou De-xing,Hao Yu-hui,Su Yong-ping(State Key Laboratory of Trauma, Burns and Combined Injury,Institute of Combined Injury,College of Military Preventive Medicine,Third Military Medical University;Chongqing,400038,China);Detoxifying effect of metallothionein and zinc on acute depleted uranium poisoning in rats[J];Acta Academiae Medicinae Militaris Tertiae;2010-04
3 LU Hao1,LIU Zong-ping2,ZHAO Bao-yu1(1.College of Veterinary Medicine,Northwest A&F University,Yangling,Shaanxi,712100,China;2.College of Veterinary Medicine,Yangzhou University,Yangzhou,Jiangsu,225009,China);Progress on Biological Functions of Metallothionein[J];Progress in Veterinary Medicine;2009-01
4 MAO Jian-ping*,FANG Jing,ZHOU Ying,CUI Yu-fang,JIANG Zhu-jun,DU Li,MA Qiong(Beijing Institute of Radiation Medicine,Beijing 100850,China);Immunomodulator,immunosuppression of radiation and immune reconstruction[J];Bulletin of the Academy of Military Medical Sciences;2010-05
5 ZHOU Yu XIE Zhenfei GENG Yanyan ZENG Xianyin (Isotope Research Lab,College of Life Science,Sichuan Agricultural University,Ya′an 625014,China);The protective effect of gingerol on anti-oxidative function and hematopoietic system in ~(60)Coγ-ray irradiated mice[J];Nuclear Techniques;2011-09
6 XU Dong-Wu1,SHI Lu1,2,JIA Xu-Guang1,2,QIAN Xiao-Ying3,TANG Lan-Lan1,ZHANG Yan-Hua1,WANG Yang1,WANG Wan-Tie1,1Department of Pathophysiology of Wenzhou Medical College,Wenzhou 325035,China;2Health School of Tongxiang,Tongxiang 314500,China;3Respiration Department of the 3rd People's Hospital of Wenzhou,Wenzhou 325000,China;Involvement of metallothionein in the protection of lung ischemic preconditioning[J];Acta Physiologica Sinica;2010-05
7 HU Zhe-wen,JIA Feng-lan,RUAN Ming,ZHANG Bao-xu (Department of Toxicology,School of Public Health,Peking University,Beijing 100083,China);Protective effects of dexamethasone on acute liver injury induced by N,N-dimethylformamide[J];Journal of Toxicology;2008-02
8 QIAN Xiaoying,WU Lifeng,SHI Lu,JIA Xuguang,XU Dongwu,WANG Yang,WANG Wantie. Department of Pathophysiology of Wenzhou Medical College,Wenzhou,325035;Effects of metallothionein in lung ischemia/reperfusion injury in rats[J];Journal of Wenzhou Medical College;2010-04
9 WANG Hong-fang1,LI Xue-jing2,XU Kun1,PU Yun1,LI Juan1(1.Department of Health Laboratory,School of Public Health,Jilin University,Changchun 130021;2.Changchun Center for Disease Controland Prevention,Changchun 130033,China);Protective effects of polysaccharides of tricholoma matsutake on the anti-oxide system of irradiated mice[J];Journal of Xi'an Jiaotong University(Medical Sciences);2011-01
10 Wang Da, Zhu Jing-ci Nursing School, Third Medical Military University of Chinese PLA, Chongqing 400038, China;Effect of Zn_7-metallothionein on lipid peroxidation of rats following deep Ⅱ skin burns[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2009-12
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 ZHENG Junheng\ RU Gang\ RU Binggen (College of Life Sciences,Peking University,Beijing,100871);Purification and Enzyme Linked Immunosorbent Assay of Human Fetal Liver Metallothionein[J];ACTA SCICENTIARUM NATURALUM UNIVERSITIS PEKINESIS;1999-02
2 Zhang Baolin Wang Wenqing Ren Hongwei(Department of Technical Physics, Peking University,Beijing 100871)Lu Jingfen(National Laboratory of the Natural and Biomimetic Drugs, Medical University of Beijing)Ru Binggen (Department of Biology, Pekiug University);ROLE OF METALLOTHIONEIN PROTECTION AGAINST RADIATION-INDUCED OXIDATIVE STRESS[J];Acta Biophysica Sinica;1992-03
3 Tie Jianke; Li Lingyuan; Ru Binggen (Deparmet of Biochemistry and Molecular biloogy. College of Life Science,Peking University, Beijing 100871)Ci Yunxiang (Collgeg of Chemistry and Molecular Engineering, Peking University, Beijing 100871);FREE RADICAL SCAVENGING AND DNA DAMAGE PROTECTION BY METALLOTHIONEIN[J];ACTA BIOPHYSICA SINICA;1995-02
4 Zhu Changshou.Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088 China.;Portions of exposure doses from varied radiation sources to Chinese population[J];CHINESE JOURNAL OF RODIATION MEDIATION AND PROTECTION;1998-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved