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《Journal of Jilin University(Medicine Edition)》 2006-05
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Effects of MT egg-milk powder on trace elements in brain and femur of lead poisoning rats

HU Xiu-li~1,RONG Hui~2,LIU Zhong-ying~1,LI Cai~ 1* (1.Department of Analyticl Biochemistry, Institute of Frontier of Medical Sciences,Jilin University, Changchun 130021,China;2.Jilin Entry-Exit Inspection and Quanrantine Burean,Changchun 130062,China)  
Objective To study the effects of MT egg-milk powder on the contents of lead,zinc,iron and copper in brain and femur of lead poisoning rats. Methods 30 Wistar rats were divided into three groups(n=10): normal control group, lead poisoning group and lead poisoning rats treated with MT egg-milk powder group. After treated with 0.2% lead acetate daily for three weeks, the rats were fed with 500 g·L~ -1 MT egg-milk powder for three weeks. At the end of the experiment,samples of brain and femur were collected for trace elements detection by atomic absorption spectroscopy. The concentration of hemoglobin was determined by haemiglobincyanide method. Results Compared with the control, the contents of zinc and hemoglobin in brain and femur were significantly decreased (P0.05), but the contents of lead and iron in brain and femur were significantly elevated(P0.01)in lead poisoning rats. After the lead poisoning rats were exposed to MT egg-milk powder, the content of lead was decreased (P0.05),the contents of hemoglobin and copper in both brain and femur were obviously increased (P0.01). Conclusion MT egg-milk powder can obviously improve the metabolism disorder of trace elements in lead poisoning rats.
【Fund】: 吉林省省科技厅资助课题(20020503-4)
【CateGory Index】: R595.2
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